Gene Information

Name : Halha_1224 (Halha_1224)
Accession : YP_007315264.1
Strain : Halobacteroides halobius DSM 5150
Genome accession: NC_019978
Putative virulence/resistance : Resistance
Product : copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1234828 - 1236660 bp
Length : 1833 bp
Strand : +
Note : PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-transloc

DNA sequence :
ATGAAGAAAAAACTAAAGATTACTAGCTTAGCAGGGATTTTAATTGCTATTGGCTGGTTAGCAGAGCTGTTTAATTTATC
ACCACTAATTTTTAATGGGGTGATGATTTTAGCAAGTATTGTAGCAGGTTATCAAGTTGCAATTAATGCCTTTAATACTC
TAAAAATGGGAGTTTTAAGTATTAATACTTTAGTAACTATTGCTGCAGGTGGTGCATTAGTGATCGGTGAGTATTGGGAA
GCAGCAGCTGTTACATTTCTTTTTGTATTTGGTAGTTATCTAGAAGCTAGAACAATGAATAAGACTAGAAATGCTATTAA
GGGATTAATGGAGCTCTCTCCTAGTACTGCAACTGTAGTCAGAAAAGGAAAAGAAGAAGAAATACCCGCTAGAGATGTTA
TAGTTGGAGAAAAAGTAATTATTAGACCAGGAGAAAAAATTCCTATTGATGGTCAGGTAATTACTGGAGAAAGCGAGGTC
AACCAAGCTTCTATTACTGGTGAATCAAAACCAGTAGCTAAAAAGCAAGGTGACGAAGTTTATAGTGGGACGATTAATAA
AGGTGGTTATTTAGAAGTTGAAGCTGAAAAAGTGGGCCAAGATACTACTTTTGCTCGGATTATCCAACTAGTTGAAGAAG
CTCAGGAAGAAAAAGCACCAACCCAAGAGTTAATGGAGAAGTTTTCTCAGTATTATACACCAGGGATTATTCTGTTAGCA
ATAATAGCTTATTTAATTACGTGGGATATTAGATTAGCTTTAACTTTATTAGTCATTGGGTGTCCTGGAGCATTAGTAAT
TTCTACTCCTATTTCTATCGTTTCTGGAATAGGTAATGCTGCTCGAAATGGAGTACTAATTAAAGGGGGTGAGCATTTAG
AAACAGCTGGAGATATAGATTGTGTAGCTTTTGATAAAACAGGAACTTTAACTCAAGGTCAGCCTGAGGTAACAGATATT
ATTGCAGTAGCAGAAACTAAAAAGAACTTATTGGCTACTGCAGCAAGTGCTGAGTTAAATTCAGAACATCATTTGGCCCA
GGCAATATTAAATGAGGTTAAAGACCAAGAGAATTTAACTAAACCTAATCAATTTTCTGTAATTACAGGAAAGGGAGTCC
AGGCTCAAGTTAATGATCAAGATATATTAGTAGGTAATAGAAAACTATTAGCTGCAGAAGAGATTAAGATAGCTGATGAT
TTAGTTGAGCAACAAGAATCTTTAGAACGCGAAGGAAAAACAGTAGTCTTTGTTACGAAAGATAAGCAAATATTAGGTTT
AATAGCTATAGCTGATACTCCAAGGGCCAAGGCCACTCAAACTATCTCTAAGCTTAAGGAGTTAGGCATAAAGAAAGTAC
TAATGTTGACAGGAGATAATCAAAGAATTGCAGCAACTATTGCCGAGCAGCTAGGTTTAGATGATTATCGAGCTGATTTA
TTACCTGAAGAAAAGGTAACTGCTATAAAAGAGTTACAACAAGAGTATACAGTAGCTATGGTAGGAGATGGAATTAATGA
TGCACCTGCTTTAGCTACAGCAGATACTGGAATAGCAATGGGAGCTGCAGGAACTGATGCTGCTATTGATACAGCAGATA
TAACTTTAATGGCGGATAAATTGACTAAACTTCCTTTTGCTTTAGGATTGAGTAAGGCTACTAATAGAAATATTAAACAG
AATGTTATCTTTGCAGTAGGTGTTGTCTTTGCTCTATTAGCAGGTGTATTAGGTAAAGAGGTATTTTTGGCTTCTGGAAT
GTTGATTCACGAGTTAAGTGTTTTATTAGTTATCTTTAATGCTATGCGTTTATTACGCTATAAAATTAATTAA

Protein sequence :
MKKKLKITSLAGILIAIGWLAELFNLSPLIFNGVMILASIVAGYQVAINAFNTLKMGVLSINTLVTIAAGGALVIGEYWE
AAAVTFLFVFGSYLEARTMNKTRNAIKGLMELSPSTATVVRKGKEEEIPARDVIVGEKVIIRPGEKIPIDGQVITGESEV
NQASITGESKPVAKKQGDEVYSGTINKGGYLEVEAEKVGQDTTFARIIQLVEEAQEEKAPTQELMEKFSQYYTPGIILLA
IIAYLITWDIRLALTLLVIGCPGALVISTPISIVSGIGNAARNGVLIKGGEHLETAGDIDCVAFDKTGTLTQGQPEVTDI
IAVAETKKNLLATAASAELNSEHHLAQAILNEVKDQENLTKPNQFSVITGKGVQAQVNDQDILVGNRKLLAAEEIKIADD
LVEQQESLEREGKTVVFVTKDKQILGLIAIADTPRAKATQTISKLKELGIKKVLMLTGDNQRIAATIAEQLGLDDYRADL
LPEEKVTAIKELQQEYTVAMVGDGINDAPALATADTGIAMGAAGTDAAIDTADITLMADKLTKLPFALGLSKATNRNIKQ
NVIFAVGVVFALLAGVLGKEVFLASGMLIHELSVLLVIFNAMRLLRYKIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 8e-93 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 7e-93 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Halha_1224 YP_007315264.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0092 Protein 2e-81 43
Halha_1224 YP_007315264.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0298 Protein 8e-79 42
Halha_1224 YP_007315264.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0461 Protein 7e-73 41
Halha_1224 YP_007315264.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0629 Protein 2e-71 41