Gene Information

Name : Metho_1314 (Metho_1314)
Accession : YP_007313066.1
Strain : Methanomethylovorans hollandica DSM 15978
Genome accession: NC_019977
Putative virulence/resistance : Unknown
Product : type I restriction-modification system methyltransferase subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1308353 - 1309870 bp
Length : 1518 bp
Strand : +
Note : TIGRFAM: type I restriction system adenine methylase (hsdM)

DNA sequence :
ATGAGTGATATTGAAAAGCAATTGTGGAAAACTGCAGACAAACTCCGGAAAAATATTGATGCCGCTGAGTATAAACACAT
AGTTCTGGGTCTGATCTTCCTGAGATATATCTCGGATGCCTTTGATGAGTTATATGAAAAACTGCAGCAGGGGGAAGGGG
AGTACGCTGGTGCGGACCCTGAGGACAGGGATGAATACAAAGCCGAGAATGTCTTCTTTGTGCCTGCAATCGCCCGCTGG
TCATATCTGCAGGCAGAAGCCAAAAAACCGGAAATCGGTAAAGCTGTTGACAATGCAATGGATGTCATCGAAAAAGAGAA
TCCGTTGCTCCGGGGCGTCTTGCCTAAGGTATATGCAAGAGGTAATCTTGATCCTGCAAATCTTGGTGGTCTGATCGATC
TGGTGAGCAATATCGCTCTCGGAGATGCAAAAAACAGGAGTGCCGATGTTCTGGGCCATGTTTTCGAGTATTTCCTTGGT
GAGTTCGCCCTTGCGGAAGGAAAGAAAGGCGGGCAGTTCTACACTCCCAGAAGCGTAGTTGAGTTACTGGTAGAAATGCT
GGAGCCTTACAATGGCCGGGTATTTGATCCATGCTGCGGTTCAGGTGGCATGTTCGTGCAGTCGGAGAAATTCGTTGCCG
ACCATCAGGGGAAGCTGAACGATATATCGATCTACGGACAGGAGAGCAACCAGACGACGTGGCGGTTGGCAAAGATGAAC
CTGGCCATCAGGAGCATTGACAGTTCCCAAGTCAAATGGAACAATGAAGGCTCTTTCCTCAATGATGTTCACAAAGACCT
GAAAGCGGATTATGTCATAGCCAACCCGCCGTTCAATGACAGCGACTGGAGCGGCGATCTGCTGCACAAGGACGGCAGGT
GGAAGTATGGTATCCCGCCGGCCGGGAACGCCAATTATGCCTGGATACAGCACTTCCTCTATCATCTTGGTCCGAGCGGC
CAGGCAGGTTTTGTCCTGGCTAAGGGTTCTCTGACATCCAAATCATCGGGCGAAGGGGATATCAGAAAAGAGCTCGTGGA
AACACGCCTGGTGGACTGCATAGTGAACCTTCCACCGAAGCTGTTCCTGAATACCCAGATCCCGGCCAGCCTCTGGTTCC
TGAGCAGGAACAAGGCCAACGGCAGGTACAGAAACAGGACGGATGAGATCCTGTTCATCGATGCACGGAACATGGGACAC
CTGATAAACCGCAGGACCCGCGAATTCTCACCTGAGGACATACAGGAGATTGCGAGCACCTACCATAAATGGCGCAATCC
GGAAGGCAATTACGAGGACGTGAAAGGATTCTGCAATTCAGCCCCCATCGCACGTGTGCGTGAGTTGGATTACGTGCTGA
CGCCCGGCCGCTATGTAGGACTGCCGGACGACGAGGATGATTTTGACTTCAATGAGCGCTTCACCGCCCTGAAAGCCGAG
TTCGAGGAGCAGCTGAAAGAGGAAGAGAGACTGAACCTGCTGATCGCCGGGAATCTGAAAAGGGTGAAGCTTGAATGA

Protein sequence :
MSDIEKQLWKTADKLRKNIDAAEYKHIVLGLIFLRYISDAFDELYEKLQQGEGEYAGADPEDRDEYKAENVFFVPAIARW
SYLQAEAKKPEIGKAVDNAMDVIEKENPLLRGVLPKVYARGNLDPANLGGLIDLVSNIALGDAKNRSADVLGHVFEYFLG
EFALAEGKKGGQFYTPRSVVELLVEMLEPYNGRVFDPCCGSGGMFVQSEKFVADHQGKLNDISIYGQESNQTTWRLAKMN
LAIRSIDSSQVKWNNEGSFLNDVHKDLKADYVIANPPFNDSDWSGDLLHKDGRWKYGIPPAGNANYAWIQHFLYHLGPSG
QAGFVLAKGSLTSKSSGEGDIRKELVETRLVDCIVNLPPKLFLNTQIPASLWFLSRNKANGRYRNRTDEILFIDARNMGH
LINRRTREFSPEDIQEIASTYHKWRNPEGNYEDVKGFCNSAPIARVRELDYVLTPGRYVGLPDDEDDFDFNERFTALKAE
FEEQLKEEERLNLLIAGNLKRVKLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 3e-138 59
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 5e-137 59
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-138 59
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-106 46