Gene Information

Name : Natoc_0614 (Natoc_0614)
Accession : YP_007308264.1
Strain : Natronococcus occultus SP4
Genome accession: NC_019974
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 597913 - 599673 bp
Length : 1761 bp
Strand : +
Note : IMG reference gene:2506729330; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGAGAAACGCGAAGATCGTCTGTACTCTGGGTCCGGCCTCGGACGACCGGGGAACGATCGCGTCGCTCGCCGACGCAGG
GATGTCCGTCGCACGGCTGAACGCGAGCCACGGCAGCCTCGAGGACCGGGCGACGCTGATCGACCGCGTGCGTGCAGTTG
ACGAGCAAAGCGACGACCCGGTCGCCGTCATGCTCGACATGAAGGGGCCGGAGGTCCGGACCGCACCGCTTCCGGACGAC
GAAACCGTCACCCTCGAGACCGGCTCCGAGATCGAGTTCGTCGAGGGCGAGGACGCCTCGCCCGACCGGGTCGGACTCTC
CCTACCCATCGAGGAAGTCGAGGCGGGAGATCGCATCTTGCTCGACGACGGGCTGATCGAGACGACCGTCCTCGAGCGCT
CGGCGGGCGTCGTTCGGGCCCGCGTCGACACCGGCGGTGAGCTCGGCGGCCGCAAGGGCGTCAACGTTCCCGGCGTCGAC
CTCGATCTCGACATCGTCACCGACTCCGACCGGAAGGACCTCGAGCTCGGCGCCGAGAAGGAAGTCGACTTCGTCGCGGC
GAGTTTCGTCCGCGACGCCGAGGACGTCTACGAGGTCAGCGAAGTCCTCGAGGAGCTCGGTGCCGAGGATGTGCCGATCA
TCTCGAAGATCGAGCGGGCGGGTGCCGTCGAGAATCTAGACGAGATCATCGACGCCTCGTATGGAATCATGGTCGCCCGG
GGGGATCTGGGCGTCGAGTGTCCGATGGAGGACGTCCCGATGATCCAGAAACGGATCATCCGCAAGTGCCACGAGGCGGG
CTCGCCAGTCATCACGGCGACGGAGATGCTCGACTCGATGGTCCACGCCCGTCGGCCGACCCGTGCGGAGGCCTCCGACG
TCGCAAACGCCGTGCTGGACGGCACGGACGGAGTCATGCTCTCGGCGGAGACGGCGATCGGCGACCACCCGACCGAGGTC
GTCGACGCCATGGACAGCATCGTCCGCGAGGTCGAGAACTCCGAGGAGTACGCCGAAACGCTCGAGCAACGCGTCCCGAC
CGCGGGCGAGGCCCGGACGGACGCGCTGGCCCGGTCCGCGCGGTACATGGCTCGGGACGTCGGTGCCGACGCGATCGTCG
CTGCGACCGAGTCCGGCTACACGGCGCTGAAGACGGCGAAGTACCGACCGGGGGTTCCGGTGGTCGCCTCGACGCCGAAC
GACGACGTTCGGCGTCGGCTCGCGCTCTCGTGGGGCGTGACGCCGCTGTACGCCCGCGTCTCCGACCAGGGGGCCGACGC
CGTCGTCGAGAAGGCGGTCCAGGCGGCGCTCGACGCCGGCGTCGCCGACAGCGGTGACACCGTCGTCGTCCTCTGTGGGA
TGATGACCGACCTCGAGGGGGCCAACACGACGAACATGATGAAGGTCCACGTCGCGGCCGACGCGTTGACGACGGGTCGA
GTCGTCGTCGAGGGGCGAACGACCGGACCGATCGCGCGTCTCCACAGCGGCGACCTCTCGACGATCCCCGACGGCGCGAT
CGTCGCCCTCGAGTCGGAGTTCGACGACGAGTTCGAGGGCGACCTCGACCGGCTCGGCGGAATCGTCAACGCCCAGCGGG
GGATGACCGGGTATCCGGCGCTGGTTGCCAGGGAGATGGACGTGCCGATGATCAGCGGCGCCGACGTCGACGAGCTCGAG
GACGGGGCGACCGTCACGCTCGACGCCGAGCGCGGCGTCGTCTACGGCGGCTCCATCGGCGATCGAACCGAACGGAACTG
A

Protein sequence :
MRNAKIVCTLGPASDDRGTIASLADAGMSVARLNASHGSLEDRATLIDRVRAVDEQSDDPVAVMLDMKGPEVRTAPLPDD
ETVTLETGSEIEFVEGEDASPDRVGLSLPIEEVEAGDRILLDDGLIETTVLERSAGVVRARVDTGGELGGRKGVNVPGVD
LDLDIVTDSDRKDLELGAEKEVDFVAASFVRDAEDVYEVSEVLEELGAEDVPIISKIERAGAVENLDEIIDASYGIMVAR
GDLGVECPMEDVPMIQKRIIRKCHEAGSPVITATEMLDSMVHARRPTRAEASDVANAVLDGTDGVMLSAETAIGDHPTEV
VDAMDSIVREVENSEEYAETLEQRVPTAGEARTDALARSARYMARDVGADAIVAATESGYTALKTAKYRPGVPVVASTPN
DDVRRRLALSWGVTPLYARVSDQGADAVVEKAVQAALDAGVADSGDTVVVLCGMMTDLEGANTTNMMKVHVAADALTTGR
VVVEGRTTGPIARLHSGDLSTIPDGAIVALESEFDDEFEGDLDRLGGIVNAQRGMTGYPALVAREMDVPMISGADVDELE
DGATVTLDAERGVVYGGSIGDRTERN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-71 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-71 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-71 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Natoc_0614 YP_007308264.1 pyruvate kinase VFG0479 Protein 3e-71 41