Gene Information

Name : Thethe_00749 (Thethe_00749)
Accession : YP_007298133.1
Strain : Thermoanaerobacterium thermosaccharolyticum M0795
Genome accession: NC_019970
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 748250 - 750001 bp
Length : 1752 bp
Strand : +
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGCGTAGAACTAAGATAATATGCACAATAGGTCCTGCAAGTGAAAAATATGAAATACTGAGAGAACTAATTGAAAGTGG
CCTAAATATTTGCAGATTAAATTTTTCTCATGGCGATCATGAAGAACATGGAAGCAGAATAGACAATATAAAAAAGATTA
GAGAAGAGCTTCAGCTGCCGATTGCTATTATGCTTGATACAAAGGGACCGGAAATAAGAACTGGGAAATTTAAAAATGGA
GTTGCTGAGCTAAAAGAGGGACAGACGTTTACGATAACCTCTAGGGATGTTGAGGGCGATGATACTATTTGTTCGGTGAC
ATATAAAGGACTTCCTCAAGATGTTGAAAGAGGTTCTCGCATATTGATAGATGATGGGTTGGTATCTTTAAAAGTCAATG
ATGTAAAAGGCGAAGACATAATATGCATAGTTGAGAATTCTGGAACGATTGGCGATCATAAAGGTGTAAATGTACCTGGA
ACCAAGTTGAATTTACCTGCTATCACGCAAAAAGATGTTGACGACATAGAATTTGGAATAAAAAAGGGTATTGATATGAT
AGCTGCATCTTTCGTGAGGAAGGCTGCAGATGTAATTGCAATAAGAAGGCTATTAGAAGATAACGATGCAGGTCACATAC
TCATCATCTCTAAGATAGAAAATCGTGAAGGTGTAGAAAATATAGACGAGATTATAAAAGTTTCAGACGGCATAATGATT
GCTCGTGGAGATTTAGGTGTAGAAATACCCATAGAAGAAATACCAATAGTTCAAAAAAGAATAATTGAGAAGTGCAATAA
AGCAGGTAAGCCAGTTGTTACTGCCACACAGATGCTTGATTCAATGATAAGAAATCCTAGGCCCACAAGAGCGGAAGTTA
CAGATGTAGCAAATGCTATATTGGATGGTACGGACGCTATAATGTTATCTGGCGAAACGGCTCAAGGGAAATATCCGGTA
GAAGCTTTTAAGACGATGTCAAAGATAGCTGAAAAAATAGAGACGTACATAAATTATAAGGAAAATATGGACAAGAACTT
TGATTACAACATCTCAATGACAAATGCTATAAGTCATGCTACATGTACAACTGCAAGGGATATTGGTGCAACAGCAATTA
TTACATCCACAATATCAGGTTACACAGCGAGAATGGTATCCCGCTATAGACCATCAGCGCCTATTATAGCGGTGACTCCG
GATAAAGGAGTAGCAAGAAGACTTAGTATTGTATGGGGTGTATATCCTTTGATATCGCAAGAAGTTAGTTCTACAGATGA
AATGATAGAGGTGTCTGTGAATACCGCACTTAATGAAGGGCTTATTCGAAATGGCGACATTGTGGTAATCTCTGCAGGAA
TACCGGTTGCTACGACAGGTACAACGAATATGTTAAAAGTCCACATAGTTGGCGATGTAATAGTAAAAGGAACGGGTATA
GGTACAAAATCAATAAGTGGCGTTGTCTCTATCATTCATGATCCATATAAAGATAAGGATAAATTTAGAGAGGGAGATAT
TATCGTTGCACAAAAAACAGAAAGAGATTATATGCCTATAATAGAGAAGGCATCGGCGATAATAACTGAAGAAGGAGGCC
TTACATCACATGCAGCAATAGTAGGGCTCAATTATGGAATACCTGTAATTGTAGGATGTGAAGGAGTTACTGCAAAACTT
AAAGATGGCATGACTGTTACGCTTGATGCAGCGAGAGGCTTAGTGTATAAGGGAATAGTAAATATAAAATAG

Protein sequence :
MRRTKIICTIGPASEKYEILRELIESGLNICRLNFSHGDHEEHGSRIDNIKKIREELQLPIAIMLDTKGPEIRTGKFKNG
VAELKEGQTFTITSRDVEGDDTICSVTYKGLPQDVERGSRILIDDGLVSLKVNDVKGEDIICIVENSGTIGDHKGVNVPG
TKLNLPAITQKDVDDIEFGIKKGIDMIAASFVRKAADVIAIRRLLEDNDAGHILIISKIENREGVENIDEIIKVSDGIMI
ARGDLGVEIPIEEIPIVQKRIIEKCNKAGKPVVTATQMLDSMIRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPV
EAFKTMSKIAEKIETYINYKENMDKNFDYNISMTNAISHATCTTARDIGATAIITSTISGYTARMVSRYRPSAPIIAVTP
DKGVARRLSIVWGVYPLISQEVSSTDEMIEVSVNTALNEGLIRNGDIVVISAGIPVATTGTTNMLKVHIVGDVIVKGTGI
GTKSISGVVSIIHDPYKDKDKFREGDIIVAQKTERDYMPIIEKASAIITEEGGLTSHAAIVGLNYGIPVIVGCEGVTAKL
KDGMTVTLDAARGLVYKGIVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-95 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-95 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-95 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-94 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thethe_00749 YP_007298133.1 pyruvate kinase VFG0479 Protein 3e-95 49