Gene Information

Name : Thethe_00349 (Thethe_00349)
Accession : YP_007297774.1
Strain : Thermoanaerobacterium thermosaccharolyticum M0795
Genome accession: NC_019970
Putative virulence/resistance : Virulence
Product : ATPase with chaperone activity, ATP-binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 348958 - 351390 bp
Length : 2433 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA)

DNA sequence :
ATGGCAATGTTTGGAAGATTTTCAGAGAAGGCACAGAAAGTGCTTTATCAGGCACAAGAGGAGGCACGTTCTCTCTATCA
CAATTATGTGGGAACAGAGCACATTCTTTTAGGTCTTATTAAAGAAGAAGATGGAATAGCATCGAGAGTTCTTAAAAATC
TCGGTGTAACGTATGATGATATAAGAGCAAAGGTAGAGACTTTGATTGGAATGGGCAATGTACCAGGAGATGTTGTGGGA
TATACTCCTAGAGCAAAGAGGGTTTTAGAGCTTAGTTTTGCTGAGGCCAGGAGATTTAATACGAATTATATTGGTACAGA
GCACATTTTATTAGGGTTAATAAGAGAAGGCGAAGGTGTAGCAGTAAGGATATTGATGGAGTTAGGTGTGGATTTTAACA
GAGTTAGAGAAGAGATAGTAAAGATGGTCAGTGAAGAACCTTCTGGTGCCGCAAATAAGGCACAAAGAGCTAAAAATACT
AATACACCTAATTTAAACCAGTTTGGAAGGGATCTAACGGATCTCGCTAGAGAAGGGAAGTTGGATCCAGTTATAGGGCG
TGAAAAAGAAATAGAAAGAGTAATACAGATATTAAGCAGAAGAACTAAAAATAACCCATGTCTTATAGGAGAGCCTGGAG
TTGGAAAAACAGCAATTGCTGAAGGATTGGCGGAAGCAATTGAAAGCGGTACAATACCAGAAATCCTTAAAGGTAAACGT
GTTGTAACTTTGGATATGGCTTCAATGGTTGCAGGCACAAAATATAGAGGAGAATTTGAGGATAGGCTAAAAAATGTTTT
AAATGAAGTCATAAAGGCAGGAAATGTCATACTGTTCATAGATGAGTTACACACAATAATAGGAGCTGGTGCTGCTGAGG
GCGCAATAGATGCATCCAATATTTTAAAACCTGCCCTTGCAAGAGGAGAAATACAAGTAATAGGTGCGACGACTATAGAT
GAGTATCGGAAATACATTGAGAAAGACCCAGCGCTCGAAAGAAGATTTCAACCTATAATGGTTGAAGAGCCGTCTGTAGA
AGAAACAATTGAAATATTAAAAGGGCTTAGAGATAAATATGAGGCACACCACAGAATAAAAATTACGGATGAAGCTATTG
AGGCTGCTGCAAAACTTTCACACAGGTATATAACAGATAGATATCTGCCTGACAAGGCTATAGACCTTATAGATGAAGCT
GCATCAAGGGTAAGATTAAAAACAGTTACAGCTCCACCAGAGATAAAAGAGTTAGAAGACAAATTAAATATGTTAAATAA
GGATAAAGAAGAGGCAATTAGAACGCAAGAGTACGAAAAGGCTGCTAAAATAAGGGATGAAGAGCAAAAGATAAAAGAAC
AGTTGGAGAATTTAAAATCAAAGTGGCAGCAGAATTCATTGGTAAAAGATAAAAGCGTCGGTGCTGAGGAGATTTCTCAG
ATTGTATCGCTGTGGACTGGAATTCCAACACAAAAATTGGCTCAAGAAGAGTCAGAAAGGCTTCTGCATTTAGAGGAAAT
ACTTCATAAACGTGTGATTGGCCAAAACGAGGCAGTTGACGCTGTAGCAAGAGCAATAAGGAGGGCAAGAGTTGGATTAA
AAGATCCTAGAAGACCTATCGGATCGTTCATATTCTTGGGACCAACTGGTGTTGGCAAGACAGAGCTTAGCAAAGCATTA
GCTGAAGCCATGTTTGGCGACGAATCAGCAATAGTTAGAATAGATATGTCAGAATATATGGAAAAATTCTCTGTATCAAG
GCTTATTGGCTCACCTCCTGGATATGTAGGATACGAAGAAGGCGGAGAACTTACAGAGAAAATAAGAAGAAAACCATATT
CTGTGATTCTCTTTGATGAGATTGAAAAGGCGCATCCTGATGTCTTCAATATACTTCTGCAGATTTTAGACGATGGAAGG
CTAACGGATTCAAAAGGCAGGACAGTAGACTTTAAGAATACGCTTATAATAATGACTTCTAATGTTGGTGCACAGCTTAT
AAAGAAGCAGACAACTTTAGGATTTATGCCTGAAGGCGAAGAGAATAAGGCATCATACGAAAAGATGAAAGAAAACATCT
TAGATGAGCTTAAAAAGTCATTTAGGCCTGAGTTTCTAAACAGGATAGATGATATTATCGTATTCCGTCAATTGACACAG
GACGACATAAGAAAAATTACTGATTTGATGATAGCTGATTTAAATAAGAGGCTGAAGGACAATAATATTAGCCTTGAATT
TACAGATGATGCTAAAGAGGAGCTTTTAAAAGAAGGCTATGATGTAACGTATGGTGCAAGACCTTTAAGAAGGGCTATAC
AAAAAGTTGTTGAAAGTGAGCTTTCAGAATTGATGTTAAAAGGTGAAGTAAAATCCGGTGATAAAATTTTAGTGAAGCTG
AAAGACGGAAAATTTGATTTTACTAAAGTGTAA

Protein sequence :
MAMFGRFSEKAQKVLYQAQEEARSLYHNYVGTEHILLGLIKEEDGIASRVLKNLGVTYDDIRAKVETLIGMGNVPGDVVG
YTPRAKRVLELSFAEARRFNTNYIGTEHILLGLIREGEGVAVRILMELGVDFNRVREEIVKMVSEEPSGAANKAQRAKNT
NTPNLNQFGRDLTDLAREGKLDPVIGREKEIERVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAEAIESGTIPEILKGKR
VVTLDMASMVAGTKYRGEFEDRLKNVLNEVIKAGNVILFIDELHTIIGAGAAEGAIDASNILKPALARGEIQVIGATTID
EYRKYIEKDPALERRFQPIMVEEPSVEETIEILKGLRDKYEAHHRIKITDEAIEAAAKLSHRYITDRYLPDKAIDLIDEA
ASRVRLKTVTAPPEIKELEDKLNMLNKDKEEAIRTQEYEKAAKIRDEEQKIKEQLENLKSKWQQNSLVKDKSVGAEEISQ
IVSLWTGIPTQKLAQEESERLLHLEEILHKRVIGQNEAVDAVARAIRRARVGLKDPRRPIGSFIFLGPTGVGKTELSKAL
AEAMFGDESAIVRIDMSEYMEKFSVSRLIGSPPGYVGYEEGGELTEKIRRKPYSVILFDEIEKAHPDVFNILLQILDDGR
LTDSKGRTVDFKNTLIIMTSNVGAQLIKKQTTLGFMPEGEENKASYEKMKENILDELKKSFRPEFLNRIDDIIVFRQLTQ
DDIRKITDLMIADLNKRLKDNNISLEFTDDAKEELLKEGYDVTYGARPLRRAIQKVVESELSELMLKGEVKSGDKILVKL
KDGKFDFTKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thethe_00349 YP_007297774.1 ATPase with chaperone activity, ATP-binding subunit VFG0079 Protein 0.0 61
Thethe_00349 YP_007297774.1 ATPase with chaperone activity, ATP-binding subunit VFG0080 Protein 7e-140 50