Gene Information

Name : Mycsm_06443 (Mycsm_06443)
Accession : YP_007295996.1
Strain : Mycobacterium smegmatis JS623
Genome accession: NC_019966
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 6395558 - 6398182 bp
Length : 2625 bp
Strand : -
Note : PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB

DNA sequence :
GTGGACATCAACAAGCTGACGCAGAAGTCGCAGGAGGCGTTGGCCGACGCGCAAAGCATCGCGACCCGGATGGGCCACAT
CGAGGTCGACGGCGAACACCTGTTGATGGCACTGATCGACCAGCCCGAGGGCCTGGTACCGCGGCTGCTCGATCAGACAG
GCGCCGACACCGCGGCGCTGCGCGCCGACCTGGAACGCGAGTTAGACCGGCGTCCGAAGGTCAGCGGTCCGGGCGCGACG
CCGGGCCAGGTCTCCGTCACCAGGCGCCTGGCGAACCTGCTGGGGGGCGCCGAGCGGGAAGCCAAGCGCCTCAAGGACGA
ATACGTGTCGGTGGAGCACCTTGTCATCGCACTCGCCGAAGAGGGTTCGGCGAGTGCCGCCGGGCGGATTCTGGCCTCCC
ACAACGTGACTCGGGACTCGTTCCTGACTGCGCTGACCAAGGTCCGTGGCAACCAGCGAGTTACCTCCGCGACCCCGGAG
GGCGCCTACGAGGCGCTGGAGAAGTACGGCCGCGACCTGGTCGCCGAAGGTCGCGCCGGCAAGCTGGACCCGGTGATCGG
ACGCGACGCCGAGATCCGCAGGGTGATCCAGATCCTCAGCCGCAAGACCAAGAACAACCCTGTGCTTATCGGCGACCCCG
GCGTCGGCAAGACCGCGATCATCGAAGGTCTGGCCCAGCGCATCGTGCGGGGCGACGTCCCAGAAGGCCTGCGCGACAAG
ACAATATTCTCCCTCGACATGGGCTCACTGGTGGCAGGGGCCAAGTACCGCGGCGAATTCGAAGAACGGCTGCAGGCGGT
GCTGTCAGAGGTGAAGGCCGGCGAGGGCCAGATCCTGCTGTTCGTCGACGAGTTACACACCGTGGTCGGTGCGGGGGCGA
CGGAGGGGTCGCTAGACGCCGGCAACATGCTCAAGCCGATGCTCGCCCGCGGTGAGCTGCACATGATCGGCGCCACCACC
CTCGACGAATACCGCAAGCACATCGAAAAGGACGCCGCGCTGGAGCGCCGGTTCCAGACCGTGCTGGTCGACGAACCTGA
CGTGGAGGACACCATATCGATCCTGCGCGGTCTGCGCGAGCGCCTCGAGGTGTTCCATGGGGTGAAGATTCAGGATGCCG
CACTGGTGGCGGCCGCCACGCTGTCGCATCGCTACATCACCGACCGCTTCCTACCCGACAAAGCGATCGATCTGGTGGAC
GAGGGCTGTGCCCGGCTGCGCACCGAAATCGACTCGATGCCAGCGGAGTTGGACGAAATTACCCGGAGGGTCACACGGCT
CGAGATCGAGGAGGCGGCGCTCGCCAAGGAAACCGACCCGGCCAGCAAGTCCCGTCTGGAGGAACTTCGGAAAGAATTGG
CCGATCTGCGAGCGGAGGCCGACGCCCGGCACGCCCAATGGGATGCCGAAAGGCAGGCCATCCGGCGGGTACAGGAACTG
CGCGGGCAGCTCGAGCAGCTACGGCACGACGCAGAAGAAGCCGAACGCAACTACGACCTCAACCGCGCCGCCGAATTGCG
CTACGGCCAGATCACCGAACTGGAGCGCAAACTGCAGGCGGCAGAGGAACAACTGCGGTCCAAGCAGGGCGAAAAGCCGC
TGCTGCGAGAGGTCGTTACCGAGGACGAGATCGCCGAAATCGTGGCCGCATGGACGGGCATACCGGTCGCGCGATTGCAG
GAGGGGGAACGGGAGAAGCTGCTGCGGCTCGACGAAATACTGCACGAGCGGGTGATCGGTCAGGATGAGGCGGTCCAGCT
GGTCTCCGATGCGGTGATTCGGGCCCGCTCCGGAATCCGTGATCCGCGCCGCCCGATCGGCTCGTTCATCTTCCTCGGGC
CCACCGGGGTCGGTAAGACCGAGCTCGCGAAGACGCTGGCCGCCGCGCTCTTCGACAGCGAGGACAACATGGTTCGGCTT
GACATGAGCGAGTACCAGGAGCGGCACACGGTCAGCCGGTTGGTCGGTGCGCCACCGGGATACGTCGGCTACGAGGAGGG
CGGCCAGCTCACCGAAGCCGTGCGTCGCAAGCCCTACTCGGTGGTCCTGCTCGACGAGATCGAAAAGGCCCACGCTGATG
TGTTCAACACCCTGCTGCAGGTGCTCGACGACGGCCGGCTCACCGATGCACAGGGACGTCAGGTTGACTTCCGCAACACA
GTGGTCATCATGACTTCCAACATCGGGTCGCACCACCTGCTCGACGGCGTCACCGCGGACGGCGAGATCAAGCCCGATGC
ACGGGACCGCGTGATGGCCGAGTTGCGCGGACACTTCAGGCCCGAGTTCCTCAACCGCGTCGACGACATCGTGCTGTTCA
CGCCGCTATCGATGCCGCAGATCGAACGGATCGTCGCGCTGCAGCTGACCGAGCTGCGGGATCGTTTGGCGGACAGGCAA
ATCGAGCTCGACATCACCCCGGACGCTCGCCGGATGATCGCCGAACACGGCTACGATCCGGTGTACGGCGCGCGACCGCT
ACGCCGCTACATCGCCCACGAGGTGGAGACCAAGATCGGCCGGGCGTTACTGCGCGGCGACATCGCGGGCGGTGGCAAGA
TCCGCGTCGCGGTGGAGAACGGCGAACTCGCCGTGGAGTATTCGGAACCGGCCCTGGCGGCCTGA

Protein sequence :
MDINKLTQKSQEALADAQSIATRMGHIEVDGEHLLMALIDQPEGLVPRLLDQTGADTAALRADLERELDRRPKVSGPGAT
PGQVSVTRRLANLLGGAEREAKRLKDEYVSVEHLVIALAEEGSASAAGRILASHNVTRDSFLTALTKVRGNQRVTSATPE
GAYEALEKYGRDLVAEGRAGKLDPVIGRDAEIRRVIQILSRKTKNNPVLIGDPGVGKTAIIEGLAQRIVRGDVPEGLRDK
TIFSLDMGSLVAGAKYRGEFEERLQAVLSEVKAGEGQILLFVDELHTVVGAGATEGSLDAGNMLKPMLARGELHMIGATT
LDEYRKHIEKDAALERRFQTVLVDEPDVEDTISILRGLRERLEVFHGVKIQDAALVAAATLSHRYITDRFLPDKAIDLVD
EGCARLRTEIDSMPAELDEITRRVTRLEIEEAALAKETDPASKSRLEELRKELADLRAEADARHAQWDAERQAIRRVQEL
RGQLEQLRHDAEEAERNYDLNRAAELRYGQITELERKLQAAEEQLRSKQGEKPLLREVVTEDEIAEIVAAWTGIPVARLQ
EGEREKLLRLDEILHERVIGQDEAVQLVSDAVIRARSGIRDPRRPIGSFIFLGPTGVGKTELAKTLAAALFDSEDNMVRL
DMSEYQERHTVSRLVGAPPGYVGYEEGGQLTEAVRRKPYSVVLLDEIEKAHADVFNTLLQVLDDGRLTDAQGRQVDFRNT
VVIMTSNIGSHHLLDGVTADGEIKPDARDRVMAELRGHFRPEFLNRVDDIVLFTPLSMPQIERIVALQLTELRDRLADRQ
IELDITPDARRMIAEHGYDPVYGARPLRRYIAHEVETKIGRALLRGDIAGGGKIRVAVENGELAVEYSEPALAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-110 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 6e-103 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycsm_06443 YP_007295996.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-120 41