Gene Information

Name : Mycsm_00642 (Mycsm_00642)
Accession : YP_007290493.1
Strain : Mycobacterium smegmatis JS623
Genome accession: NC_019966
Putative virulence/resistance : Virulence
Product : response regulator with CheY-like receiver domain and winged-helix DNA-binding domain
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 668135 - 668836 bp
Length : 702 bp
Strand : -
Note : PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal

DNA sequence : 
ATGACGCGAGTGCTGATCGCCGACGACGACATCGTGGTGGGCGATGTCGTGCGTCGATACCTGGAGCGCGACGGCCTCGA
CGTCTCGATCGCACACGACGGTACGGAGGCGCTGCGACTGCTCGGCTCTCAGCGCATTGACGTCGCGGTGCTCGACGTGA
TGATGCCCGGACCGGACGGTCTGACGCTGTGCCGCAATCTGCGGCAGCGCAGCGGCTACACCATGCCCGTGATCCTGCTG
ACCGCGCTTGGCGAGGAAGACGACCGCATCGCCGGCCTGGAGGCCGGAGCAGACGACTACTTGACCAAGCCGTTCAGCCC
GCGGGAGTTGGCCCTGCGCGTGCGTTCGGTGCTGCGGCGATCACCGTCGCCGTCGAGCGTGCTGCCGCTGGATCTCGCCG
TTGGGAACATGACCGTGTCCACGGCCGCCCGCTCGGTGACCATCGACGGGCAGCCGGTCAGCCTGACCAACCGTGAGTTC
GACTTGTTGATGTTCTTCCTCACCCACACCGACACCGTGTTCTCCCGTGAGGCGCTGTTAAAGCAGGTGTGGCACTGGGA
CTTTGGTGATCTGTCGACAGTCACCGTGCACGTCAAACGCCTGCGCTCCAAGCTCGGCGAACACCACCGGGTGCAGACGG
TGTGGGGCCGGGGATATCTGTGGATCGGCGGCGATGAGCGCCTGCGCGAGGAGCAATCCTGA

Protein sequence : 
MTRVLIADDDIVVGDVVRRYLERDGLDVSIAHDGTEALRLLGSQRIDVAVLDVMMPGPDGLTLCRNLRQRSGYTMPVILL
TALGEEDDRIAGLEAGADDYLTKPFSPRELALRVRSVLRRSPSPSSVLPLDLAVGNMTVSTAARSVTIDGQPVSLTNREF
DLLMFFLTHTDTVFSREALLKQVWHWDFGDLSTVTVHVKRLRSKLGEHHRVQTVWGRGYLWIGGDERLREEQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mprA YP_005680459.1 response regulator mprA Not tested PiCp 3 Protein 3e-25 41
mprA YP_005682550.1 response regulator mprA Not tested PiCp 3 Protein 3e-25 41
tcsR1 YP_003782583.1 two-component system transcriptional regulatory protein Not tested PiCp 3 Protein 3e-25 41
mprA YP_005684640.1 response regulator mprA Not tested PiCp 3 Protein 3e-25 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycsm_00642 YP_007290493.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain FJ349556.1.orf0.gene Protein 7e-33 42
Mycsm_00642 YP_007290493.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain AE000516.2.gene3505. Protein 2e-26 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycsm_00642 YP_007290493.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain VFG1389 Protein 1e-25 43
Mycsm_00642 YP_007290493.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain VFG1390 Protein 2e-27 41