Gene Information

Name : Mycsm_05414 (Mycsm_05414)
Accession : YP_007295010.1
Strain : Mycobacterium smegmatis JS623
Genome accession: NC_019966
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5368808 - 5370310 bp
Length : 1503 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGACTATTGCCGCCGAAGCAACCAGGCTCGACCCGCGTGTGGTCGAATTCGTGTCGACGCCGAAGCAGATGTTCGTCGA
CGGACAGTGGGTCGACGCGCTCTCCGGCCGGCGCTTCGAAACCGTCGACCCCGCCACCGAAGAGGTGATCACCACGGTGC
CGCACAGCGGCGTCGAGGACGTCGAAAAGGCCGTCAAAGCCGCGCGGCGCGCATTCGACGAGGGCCCGTGGCCGTCGCTC
ACCCCGGCCGAGCGCCAGCAGATCATCTGGCGCATCGCCGATGGCATCACCGCGCGCGCCGACCAGTTCGCGCAGCTGGA
AACGCTCGACAACGGCAAGTCGGTGACCGTCGCCAAAGCCGTCGACGTGACGTGGGCCGCGGAGATCTTCTACTACTACG
CCGGCTGGGCCACCAAGATCGAGGGCCGCACCATCCCGGTGTCGGTGCCGTGGGCGCCGGGCGGCCGGTTCCACGCCTTC
ACGCTGCGCGAGCCGGTCGGCGTGTGCGCGCAGATCATCCCCTGGAATTTCCCGCTGGTGATGGCGGCCTTCAAGGTCGC
GCCAGCGCTTGCGTGCGGCAACACCGTGATCCTCAAGCCGGCCGAGCAGACACCGCTGACCGCGCTGCTGCTGGCCGAGG
TCATCGCCGACGCCGGCGTACCGGACGGAGTTGTCAACGTGCTCACCGGATTCGGCGACATCGGTGCGGCGCTGTCCGCG
CACTCCGACGTCGACAAGGTCGCGTTCACCGGGTCGACCGAGGTCGGCCGCAAGATCGTCAACGCCGCATCGGGCAACCT
CAAGAAGGTCTCGCTGGAACTCGGCGGCAAGAGCCCGCAGGTCGTCTTCGCCGACGCCGACCTGGACGCGGCTATCCCCG
GCGCTGCCAGTGGCTTCCTGTTCAACCACGGCCAGACCTGCACGGCCGGCACCCGGTTGCTCGTCGAGGACCGCATCTTC
GACGAGTTCACCGAGGGCGTGGCCGATCTCGCACGGGCGCAGAAGATCGGCCCGGGACTGGACCCGACCAACGACATCGG
CCCGCTGGTGTCGCGTGAACAGCTGACGAAGGTCACCGGATACCTCGATGCAGGCGTTCAACACGGCGCCCGGGCGCTGG
CCGGCGGCGGCCGCCACGGCGACACGGGGTTCTACGTGCAGCCCAGCCTGCTGGTCAACGTGCGGCCCGACTTCAGCGTC
TACCGCGAAGAGATCTTCGGGCCGGTCGCCGTCGCGATTCCGTTCAACCGCGACCAGGGCGTGCGCGCCGCCGCCAACGA
CACCCCGTACGGGCTGGCCGCCAGCGTGTGGACCCGCGACGTGTCGACGGCACATGCGGTCGCGGCGCAGATCAAGGCGG
GCACGGTGTGGGTGAATTGCCATAACGCATTCGATACTGCCCTTCCATTCGGCGGCTACAAACAATCCGGCTGGGGCCGC
GAACTCGGCGAGGGTGCGATCGCCGAATACACCCAAACGAAGGCCGTCAATATGGCCCTGTAA

Protein sequence :
MTIAAEATRLDPRVVEFVSTPKQMFVDGQWVDALSGRRFETVDPATEEVITTVPHSGVEDVEKAVKAARRAFDEGPWPSL
TPAERQQIIWRIADGITARADQFAQLETLDNGKSVTVAKAVDVTWAAEIFYYYAGWATKIEGRTIPVSVPWAPGGRFHAF
TLREPVGVCAQIIPWNFPLVMAAFKVAPALACGNTVILKPAEQTPLTALLLAEVIADAGVPDGVVNVLTGFGDIGAALSA
HSDVDKVAFTGSTEVGRKIVNAASGNLKKVSLELGGKSPQVVFADADLDAAIPGAASGFLFNHGQTCTAGTRLLVEDRIF
DEFTEGVADLARAQKIGPGLDPTNDIGPLVSREQLTKVTGYLDAGVQHGARALAGGGRHGDTGFYVQPSLLVNVRPDFSV
YREEIFGPVAVAIPFNRDQGVRAAANDTPYGLAASVWTRDVSTAHAVAAQIKAGTVWVNCHNAFDTALPFGGYKQSGWGR
ELGEGAIAEYTQTKAVNMAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-73 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-75 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-79 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-79 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-79 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-78 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycsm_05414 YP_007295010.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 5e-76 41