Gene Information

Name : Mycsm_05082 (Mycsm_05082)
Accession : YP_007294695.1
Strain : Mycobacterium smegmatis JS623
Genome accession: NC_019966
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase/cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.1
Position : 5029156 - 5030310 bp
Length : 1155 bp
Strand : -
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme

DNA sequence :
ATGACTGAGCACAAATACCAGGGCCTGGCCACGAAGGCCATCCACGCGGGTTTTCGACCAGACCCGGGCACCGGCGCGGT
CAACGCCCCGATCTACGCGAGTTCGACGTTCGCGCAGGACGGCGTCGGCGGGTTGCGCGGAGGATTCGAGTACGCCCGCA
CCGGCAACCCGACGCGCGCGGCGCTCGAGGCGTCGCTGGCCGCGGTGGAGGAGGCGACGTTCGGGCGGGCCTTCTCCTCA
GGTATGGCGGCCACCGACTGTGTGCTGCGCGCGGTGCTCCGGCCAGGCGATCACATCGTCATGCCCGACGACGCCTACGG
TGGTACCTTCCGGCTGATCGACAAGGTGTTCACGCAGTGGGGGATCGGCTACTCGGCGGTCGCGCTGTCTGACGTCGACG
CTGTCCGCGAGGCGATCACACCGAAGACGCGCATGATCTGGTTGGAGACACCGACCAACCCATTGCTGTCGGTCGCCGAC
ATCTCCGCGATCGCACAACTAGCGGCGCCGTCGAACATAAAGGTGTTGGTGGACAACACGTTTGCCTCGCCCGCACTGCA
GCAGCCGCTGACGCTCGGCGCCGACATCGTGCTGCATTCGACGACGAAATACATCGGCGGACACTCCGATGTGGTCGGCG
GCGCGCTGTTGACGAACGACGAAGAACTCGACAACGCGTTCGCCTTCCTGCAGAACGGCGCGGGCGCGGTGCCGGGTCCA
TTCGATGCGTACTTGACGATGCGCGGGCTCAAGACGCTGGTGCTGCGGATGCAGAAGCACAGCGAGAACGCCGCAACGGT
AGCCGAGTTCCTCGACAACCATCCGGCAATCGAAACCGTGCTCTATCCGGGCCTGCCCAGCCATCCCGGCCACGAAGTAG
CCAAGCGACAGATGAGCGCTTTCGGCGGCATGGTGTCGGTGCGAATGCGTGGCGGACCGCAAGCGGCGCACGACTTCTGC
TCTCGGACAGAGATTTTCATTCTTGCTGAGTCGTTGGGCGGGGTCGAGTCGCTGATCGAATATCCGGGCGCGATGACGCA
CGCGTCGACCGCGGGCTCGCAGCTGGAGGTGCCCGACGACCTGGTGCGACTGTCGGTCGGCATTGAAGATCCCGCCGACC
TGCTCGCCGACGTGGAGCAGGCGCTAAGAAGCTAG

Protein sequence :
MTEHKYQGLATKAIHAGFRPDPGTGAVNAPIYASSTFAQDGVGGLRGGFEYARTGNPTRAALEASLAAVEEATFGRAFSS
GMAATDCVLRAVLRPGDHIVMPDDAYGGTFRLIDKVFTQWGIGYSAVALSDVDAVREAITPKTRMIWLETPTNPLLSVAD
ISAIAQLAAPSNIKVLVDNTFASPALQQPLTLGADIVLHSTTKYIGGHSDVVGGALLTNDEELDNAFAFLQNGAGAVPGP
FDAYLTMRGLKTLVLRMQKHSENAATVAEFLDNHPAIETVLYPGLPSHPGHEVAKRQMSAFGGMVSVRMRGGPQAAHDFC
SRTEIFILAESLGGVESLIEYPGAMTHASTAGSQLEVPDDLVRLSVGIEDPADLLADVEQALRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-72 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-73 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-56 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycsm_05082 YP_007294695.1 cystathionine beta-lyase/cystathionine gamma-synthase BAC0207 Protein 6e-63 42