Gene Information

Name : Mycsm_00451 (Mycsm_00451)
Accession : YP_007290308.1
Strain : Mycobacterium smegmatis JS623
Genome accession: NC_019966
Putative virulence/resistance : Unknown
Product : hydroxymethylpyrimidine synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 490514 - 492076 bp
Length : 1563 bp
Strand : -
Note : PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC

DNA sequence :
ATGACGCTGCTTGATTCCGCTTCTGTTTCTGTCACCACCGGCCCGATCGTGGGCAGCACCAAGATCTACGTCGACGGGGT
TCCGTTTCGGCGGGTGAATCTGACCAACGGCGAGTACCTGGATCTGTACGACACCTCCGGTCCGTACACCGATCCGGACG
CGGAGATTGATCTGCACCGAGGCTTGTCGCCGCGCCCCGGTGTTGTCCGCGAAGAGGGCACGCAGTTGCAGCGCGCCCGT
AATGGTGAGATCACCGCGGAGATGGCGTTCATCGCCGCCCGCGAAGGCATGCCCGCCGAGCTGGTTCGCGACGAGGTCGC
CGCCGGTCGCGCGGTGATCCCGGCCAACCACAACCACCCGGAGAGCGAGCCGATGATCATCGGTAAGGCGTTCGCGGTGA
AAATTAATGCCAACATTGGCAATTCGGCTGTCACAAGCTCCATCGCCGAAGAGGTCGACAAGATGGTGTGGGCTACGCGC
TGGGGCGCCGACACCATCATGGATCTGTCGACCGGCCGCAACATCCATGAGACGCGCGAATGGATCCTGCGCAATTCGCC
GGTCCCCGTCGGCACCGTCCCGATCTACCAGGCCCTCGAAAAAGTCAATGGCGATCCCACCCAACTCAGCTGGGAGGTCT
ACCGCGACACCGTGATCGAGCAATGCGAGCAGGGTGTGGACTACATGACCGTGCACGCCGGCGTGCTGCTGCGCTACATT
CCGCTGACCGTCAAGCGCGTCACCGGCATCGTCAGCAGGGGCGGCTCGATCATGGCGGCCTGGATGCTGGCGCATCACAG
CGAGTCGTTCCTCTACACGAATTTCGCGGAGCTCTGCGAGATCCTGGCCCGCTACGACGTCACCTTCTCGCTGGGTGACG
GCCTGCGTCCAGGCTCGATCGCCGACGCCAACGACGAGGCGCAGTTCTCGGAGCTGAGAACGCTTGGCGAGCTGACCAAG
ATCGCGAAAGCCCATGGCGTGCAGGTGATGATCGAGGGGCCGGGCCACATCCCCATGCACAAGATCGTCGAGAACGTGCG
CCTCGAAGAGGAGCTCTGCGAGGAGGCGCCGTTCTACACCCTCGGCCCGCTGGCCACCGACATCGCGCCCGGCTATGACC
ACATCACCAGCGCCATCGGGGCCTCGATCATCGCCCAGGCCGGCACCGCGATGCTGTGCTATGTCACACCCAAGGAGCAC
CTGGGCCTGCCGGACCGCAACGACGTCAAGGTCGGCGTGATCACCTACAAGATCGCTGCGCACGCAGCCGATCTCGCGAA
GGGGCACCCGCGTGCGCAGGAGCGTGACGACGCATTGTCAAAGGCCCGCTTCGAGTTTCGCTGGCACGACCAGTTCGCGC
TGTCACTCGATCCGGACACCGCGCGCGAATTCCACGACGAGACACTGCCCGCGGAGCCCGCCAAGACCGCGCACTTCTGC
TCGATGTGCGGGCCGAAGTTCTGCTCGATGCGCATCACCCAGGACATCCGCGACGCGATGGCAGAGAAGTCCAGGGAGTT
CGCCGAACACGGAAACCAGGTCTATCTACCCTTGGCTACATGA

Protein sequence :
MTLLDSASVSVTTGPIVGSTKIYVDGVPFRRVNLTNGEYLDLYDTSGPYTDPDAEIDLHRGLSPRPGVVREEGTQLQRAR
NGEITAEMAFIAAREGMPAELVRDEVAAGRAVIPANHNHPESEPMIIGKAFAVKINANIGNSAVTSSIAEEVDKMVWATR
WGADTIMDLSTGRNIHETREWILRNSPVPVGTVPIYQALEKVNGDPTQLSWEVYRDTVIEQCEQGVDYMTVHAGVLLRYI
PLTVKRVTGIVSRGGSIMAAWMLAHHSESFLYTNFAELCEILARYDVTFSLGDGLRPGSIADANDEAQFSELRTLGELTK
IAKAHGVQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPGYDHITSAIGASIIAQAGTAMLCYVTPKEH
LGLPDRNDVKVGVITYKIAAHAADLAKGHPRAQERDDALSKARFEFRWHDQFALSLDPDTAREFHDETLPAEPAKTAHFC
SMCGPKFCSMRITQDIRDAMAEKSREFAEHGNQVYLPLAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 3e-150 70
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 3e-150 70
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 5e-146 63