Gene Information

Name : Mycsm_03281 (Mycsm_03281)
Accession : YP_007292992.1
Strain : Mycobacterium smegmatis JS623
Genome accession: NC_019966
Putative virulence/resistance : Virulence
Product : urease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3223992 - 3225713 bp
Length : 1722 bp
Strand : +
Note : PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit

DNA sequence :
ATGACTCAGCTTTCGCGCGCCCGTTACGCCACGCTGTTCGGCCCGACCACCGGCGACCGGATCCGGCTCGCCGACACCGA
CCTGGTCATCGAGATCACCGAAGACCGCAGCGGCGGCCCCGGATTGGCGGGCGACGAGGCGGTGTTCGGCGGCGGCAAGG
TGCTTCGCGAGTCGATGGGGCAGGGTCGCGTCAGCCGCGCCGACGGCGCACCCGACACCGTCATCACCGGGGTGGTGATT
CTCGACTACTGGGGAATCATCAAGGCCGACATCGGAATTCGCGACGGGCGCATCGTCGCGATCGGCAAGGCCGGTAACCC
GGACATCATGTCCGGTGTGCATCCCGACCTCGTGGTCGGCCCGTCGACCGAGATCATCGCGGGCAACGGCCGCATCGTCA
CCGCGGGCGCCATCGACTGCCATGTGCACCTGATCTGCCCCCAGATCATGGAGGAGGCGCTGGGCGGTGGCATCACCACC
ATCATCGCGGGCGGCACCGGGCCCGCCGAAGGCAGTAAGGCGACCACCGTCACCCCGGGGTCCTGGCATCTAGCCCGCAT
GCTCGAAGCCCTCGACTCGTGGCCGCTGAACATCGCGCTTCTCGGCAAGGGAAACACCGTCAGCGCCGATTCGATGTGGG
AGCAATTGCGTGGTGGCGCAGCGGGATTCAAGCTGCACGAGGACTGGGGGACGACACCTGCGGCAATCGACGCTTGCCTG
ACGGTGTCGGAATCTGCCGGCGTGCAGGTCAACATCCACACCGACACGCTGAACGAGGCAGGCTTCGTCGAGGACACGCT
GGCCGCGGTCAAGGGACGCTCGATACACGCCTATCACACCGAAGGCGCCGGCGGTGGCCACGCACCCGACATCATCACCG
TGGTCTCACACGGCAATGTGCTACCGAGTTCGACGAACCCGACCCGGCCGCACACGGTCAACACGCTCGACGAGCACCTC
GACATGCTGATGGTGTGCCATCACCTGAACCCCAGTGTCCCTGAGGATCTCGCATTCGCCGAGAGTCGCATCCGGCCCTC
GACCATTGCCGCCGAGGATCTGCTGCACGACATCGGCGCGATCTCGATGATCGGCAGCGACGCGCAGGCGATGGGCCGCA
TCGGTGAGGTGGTGCTGCGCACCTGGCAGACCGCGCACGTGATGAAGCGTCGGCGCGGTGCGCTGGACGGCGACGGGAAG
GCCGACAACAACCGGGCCCGGCGTTACGTCGCGAAATACACGATCTGCCCGGCCGTCGCCCACGGCCTCGACGACCACAT
CGGCTCGGTCGAGGTCGGCAAGCTCGCCGACCTGGTGCTGTGGGAGCCTGCGTTCTTCGGCGTCCGCCCGCACGCGGTGC
TCAAGGGCGGCATGATCGCCTGGGCCGCAATGGGAGACGCCAACGCCTCGATCCCGACGCCGCAACCGGTGCTGCCGCGG
CCGATGTTCGGCGCCGCACCCGCAGCAGCCGCGGCCACGTCAGTCCACTTCGTTTCGCCGCAAGCCGTCGAGGATGGACT
GGCCGACCGACTCGCTGTCAACCGAAAACTGTTTGCGGTCAAAAACGTTCGGCAAGTCGGTAAAGCTCAGATGCCGCTCA
ACGATGCACTGCCGAGCATCGAGGTCGATCCGGACACCTTCACCGTGCGCATCGACGGCGATGTGTGGCAGGAGCAGCCC
GCCGCCGAATTGCCGATGGCGCAAAGGTATTTCCTGTTCTGA

Protein sequence :
MTQLSRARYATLFGPTTGDRIRLADTDLVIEITEDRSGGPGLAGDEAVFGGGKVLRESMGQGRVSRADGAPDTVITGVVI
LDYWGIIKADIGIRDGRIVAIGKAGNPDIMSGVHPDLVVGPSTEIIAGNGRIVTAGAIDCHVHLICPQIMEEALGGGITT
IIAGGTGPAEGSKATTVTPGSWHLARMLEALDSWPLNIALLGKGNTVSADSMWEQLRGGAAGFKLHEDWGTTPAAIDACL
TVSESAGVQVNIHTDTLNEAGFVEDTLAAVKGRSIHAYHTEGAGGGHAPDIITVVSHGNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLNPSVPEDLAFAESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVLRTWQTAHVMKRRRGALDGDGK
ADNNRARRYVAKYTICPAVAHGLDDHIGSVEVGKLADLVLWEPAFFGVRPHAVLKGGMIAWAAMGDANASIPTPQPVLPR
PMFGAAPAAAAATSVHFVSPQAVEDGLADRLAVNRKLFAVKNVRQVGKAQMPLNDALPSIEVDPDTFTVRIDGDVWQEQP
AAELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 6e-157 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 6e-157 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-155 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 9e-156 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-156 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-156 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycsm_03281 YP_007292992.1 urease VFG0270 Protein 2e-138 54