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Name : Mycsm_02993 (Mycsm_02993) Accession : YP_007292721.1 Strain : Mycobacterium smegmatis JS623 Genome accession: NC_019966 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : - COG ID : - EC number : 2.7.1.40 Position : 2934776 - 2936206 bp Length : 1431 bp Strand : + Note : PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase DNA sequence : ATGCTTCTCGGCGTGAATAGACGCGGGAAAATCGTCTGTACGCTCGGTCCGGCCACTGCCACCGACGAGACCTTGACGGC TCTGGTTGAGGCCGGGATGGACGTCGCACGGCTCAACTTCAGCCACGGCGACTACGCCGATCACGAGGCCAACTACAAGC GGGTTCGCGCCGCTTCCGACCTGACTGGGCACGCCGTCGGCATCATGGCCGACCTACAGGGCCCCAAGATCCGCCTTGGT CGATTCAAGGACGGTCCGACCTTCTGGGCCAACGGCGAAACGGTGCGCATCACCGTCGATGACTGCGAAGGCTCCCACGA CCGGGTGTCCACCACCTACAAGCGACTGGCCCAGGACGCCACGCCAGGAGACCGGGTGCTCGTCGACGACGGCAACGTGG GCCTCCTCGTTGACACCATCGAGGGCAACGACGTCGTCTGCACCGTCACCGAGGGCGGGCCGGTCAGTAACAACAAGGGC ATGTCGCTGCCCGGCATGAATGTGTCCGCCCCCGCGCTGTCGGGCAAGGACATCGACGACCTCGAATTCGCGTTGAAGCT CGGCGTCGACCTCGTCGCGTTGTCGTTCGTCCGCTCGCCCGCAGACATCGAACTCGTGCACGAGATCATGGACCGCGTCG GCAGGCGGGTTCCGGTGATCGCCAAGCTCGAAAAACCGGAAGCCATCGACAATCTCGAGGCGATCGTGCTGGCATTCGAC GCGATCATGGTGGCCCGCGGTGACCTCGGCGTCGAACTGCCGCTCGAGGAAGTGCCGCTGGTGCAGAAGCGTGCCATCCA AATGGCAAGGGAGAACGCCAAACCCGTCATCGTCGCCACTCAGATGCTGGAGTCGATGATCGAGAATTCGCGGCCGACCC GCGCCGAAGCGTCCGACGTCGCCAACGCCGTGCTCGACGGCGCGGACGCGGTGATGCTCTCGGGTGAGACGTCGGTCGGC AAGTTCCCGCTCGAAGCCGTCAAGACGATGGCTCGCATCATCCATGCGGTCGAGGAGAATTCGGTGGCCGCACCGCCTCT CGCGCACGTGCCGCGCACCAAGCGCGGCGTCATCTCGTATGCGGCCCGCGATATCGGCGAACGCCTGGACGCCAAGGCAC TTGTGGCCTTCACCCAATCCGGCGACACCGTGCGCAGGCTTGCGCGGTTGCACACCCCGCTGCCGGTGCTGGCGTTCACG TCCCTGCCCGAGGTGCGCAGCCAATTGGCGCTGACGTGGGGCACCGAGACGTTCATCGTGCCGCATATCGCCAGTACTGA CGGCATGATCCGCCAGGTGGACAAGTCGCTGCTGGAGCTCGGCCGCTACAAGCGCGGCGAGCTGGTGGTCATCGTCGCGG GCGCACCGCCTGGCACAGTAGGCTCCACGAACCTGATCCACGTGCACCGGATCGGGGAGGAAGACGTTTAG Protein sequence : MLLGVNRRGKIVCTLGPATATDETLTALVEAGMDVARLNFSHGDYADHEANYKRVRAASDLTGHAVGIMADLQGPKIRLG RFKDGPTFWANGETVRITVDDCEGSHDRVSTTYKRLAQDATPGDRVLVDDGNVGLLVDTIEGNDVVCTVTEGGPVSNNKG MSLPGMNVSAPALSGKDIDDLEFALKLGVDLVALSFVRSPADIELVHEIMDRVGRRVPVIAKLEKPEAIDNLEAIVLAFD AIMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLESMIENSRPTRAEASDVANAVLDGADAVMLSGETSVG KFPLEAVKTMARIIHAVEENSVAAPPLAHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPVLAFT SLPEVRSQLALTWGTETFIVPHIASTDGMIRQVDKSLLELGRYKRGELVVIVAGAPPGTVGSTNLIHVHRIGEEDV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-65 | 42 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-65 | 42 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-65 | 42 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 3e-65 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Mycsm_02993 | YP_007292721.1 | pyruvate kinase | VFG0479 | Protein | 5e-66 | 42 |
