Gene Information

Name : Mycsm_01088 (Mycsm_01088)
Accession : YP_007290916.1
Strain : Mycobacterium smegmatis JS623
Genome accession: NC_019966
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1103297 - 1104820 bp
Length : 1524 bp
Strand : +
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGACCGTGTACGCCCGACCGGGTACCGAACGCTCGGTGATGTCGTTCAAGTCCCGGTACGAGAACTACATCGGCGGGCA
GTGGGTAGCGCCCACCGCTGGCCGGTACTTCGAGAACGCCAGCCCGGTCAACGGTTTGCCGTTCTGCGAGATCCCCCGCT
CCGATGAGGCCGACATCGAGAAGGCGCTCGATGCCGCCCACGCCGCCGCGCCGGCCTGGGGCAAAACGACGGCAGCCGAA
CGGGCGGTGATCCTCAACAAGATCGCCGACCGCATCCAGGAGAACCTCGAATCGATCGCCGTCGCCGAGTCATGGGACAA
CGGCAAGCCAGTACGTGAGACGCTGAACGCCGATATCCCGTTAGCCATCGACCATTTCCGGTACTTCGCCGGTGCCATCC
GCGCGCAGGAGGGGTCGCTGTCGCAGATCGACGACGAAACCGTCGCCTACCACTTCCACGAACCCCTTGGCGTCGTCGGC
CAGATCATCCCGTGGAACTTTCCTATCCTGATGGCCACCTGGAAGCTGGCGCCGGCGATCGCGGCGGGAAATGCCGTGGT
GCTCAAGCCAGCTGAGCAGACGCCGGCCTCGATCCTGTACTTGTTCGAACTGATCGGTGATCTGCTGCCGCCCGGCGTGG
TGAACATCGTCAACGGGTTCGGCCTCGAGGCGGGCAAGCCGCTTGCGTCGTCGAAGCGGATCTCCAAGATCGCGTTTACC
GGTGAGACCACCACCGGTCGGCTGATCATGCAATACGCATCGCAGAACCTGATCCCCGTCACGCTGGAGCTGGGCGGCAA
GAGCCCGAACATCTTCTTCAACGACGTTATGGCCCAGCACGACGACTACCAGGACAAGGCGCTCGAAGGGTTCACCATGT
TCGCCCTCAACCAGGGCGAGGTCTGCACATGTCCGTCCCGCAGCCTGATTCAGGCCGACATCTTCGATGAGTTCCTTGAA
CTGGCCGCGATCCGCACGAAGGCGGTCCGGCAGGGTGACCCGCTGGACACCGAGACGATGATCGGCGCGCAGGCATCGGA
GGACCAGATGGAAAAGATCCTGTCCTACATCGACATCGGCAAGAGGGACGGCGCAAAGCTCGTCACCGGCGGCCACCGCG
CCGAACTCGGCGGCGATCTGGGCGGCGGATATTACGTCACCCCAACGGTTTTCACCGGAACCAACGATATGCGCATCTTC
CAGGAGGAGATCTTCGGCCCGGTGGTGGCGGTGACGTCGTTCACCGACTACGACGACGCGATCAACATCGCCAATGACAC
GCTCTACGGCCTTGGTGCAGGGGTGTGGAGCCGCGACGGCAACGTCGCCTACCGAGCGGGCCGCGACATCAAGGCCGGCC
GGGTGTGGACCAACTGCTACCACGCATATCCCGCGCACGCTGCGTTCGGCGGCTACAAGCAGTCGGGCATCGGCCGTGAG
ACCCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTCGTCTCCTACAGCAACAAGGCCCAAGGCTTCTT
CTGA

Protein sequence :
MTVYARPGTERSVMSFKSRYENYIGGQWVAPTAGRYFENASPVNGLPFCEIPRSDEADIEKALDAAHAAAPAWGKTTAAE
RAVILNKIADRIQENLESIAVAESWDNGKPVRETLNADIPLAIDHFRYFAGAIRAQEGSLSQIDDETVAYHFHEPLGVVG
QIIPWNFPILMATWKLAPAIAAGNAVVLKPAEQTPASILYLFELIGDLLPPGVVNIVNGFGLEAGKPLASSKRISKIAFT
GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVMAQHDDYQDKALEGFTMFALNQGEVCTCPSRSLIQADIFDEFLE
LAAIRTKAVRQGDPLDTETMIGAQASEDQMEKILSYIDIGKRDGAKLVTGGHRAELGGDLGGGYYVTPTVFTGTNDMRIF
QEEIFGPVVAVTSFTDYDDAINIANDTLYGLGAGVWSRDGNVAYRAGRDIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRE
THKMMLDHYQQTKNLLVSYSNKAQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-144 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-153 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-153 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-153 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-153 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-68 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mycsm_01088 YP_007290916.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 8e-145 62