Gene Information

Name : BN43_10497 (BN43_10497)
Accession : YP_007286337.1
Strain : Mycobacterium canettii CIPT 140070008
Genome accession: NC_019965
Putative virulence/resistance : Virulence
Product : Putative aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 547986 - 549509 bp
Length : 1524 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12657046, 12775759; Product type pe : putative enzyme

DNA sequence :
ATGACTGTCTTTTCCCGTCCCGGTTCCGCCGGGGCGCTGATGTCCTATGAATCCCAGTACCGAAACTTCATCGGGGGCCA
GTGGGTCGCGCCGGTCCATGGGCGCTACTTCGAGAACCCGACGCCGGTGACCGGCCAGCCGTTCTGCGAGGTGCCGCGCT
CCGACGCGGCCGACATCGACAAGGCGCTCGACGCCGCGCACGCGGCGGCGCCGGGGTGGGGCAAGACCGCACCGGCCGAA
CGGGCGGCGATCCTCAACAAGATCGCCGACCGCATCGACAAGAACGCCGCCGCGCTGGCGGTGGCCGAGGTCTGGGACAA
CGGGAAACCGGTCCGGGAAGCGCTGGCCGCCGATATCCCGTTGGCGGTCGATCACTTCCGGTACTTCGCCGCGGCGATCC
GCGCCCAGGAGGGCGCGCTGAGCCAGATCGACGAGGACACCGTGGCCTACCACTTCCACGAGCCGCTCGGCGTGGTGGGC
CAGATCATTCCGTGGAACTTCCCCATCCTGATGGCGGCCTGGAAGCTGGCGCCGGCGTTGGCGGCGGGCAACACGGCGGT
GCTCAAACCCGCCGAGCAGACACCCGCCTCGGTGCTCTACCTGATGTCGCTGATCGGTGATCTGTTGCCGCCCGGGGTGG
TCAACGTGGTCAACGGATTCGGCGCCGAGGCCGGCAAGCCGTTGGCCTCCAGCGACCGCATCGCCAAGGTCGCGTTCACC
GGGGAAACCACCACGGGGCGGCTGATCATGCAATACGCCTCGCACAACCTGATCCCGGTCACCCTGGAACTCGGCGGCAA
GAGCCCCAACATCTTCTTCGCCGACGTGCTGGCCGCCCACGACGACTTCTGCGACAAAGCGCTGGAAGGCTTCACCATGT
TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGGAGTCTGATCCAGGCCGACATCTACGACGAGTTCCTGGAG
CTGGCGGCGATCCGGACCAAGGCGGTCCGCCAAGGCGATCCGCTGGACACCGAAACCATGCTGGGTTCCCAGGCCTCCAA
CGACCAGCTGGAAAAGGTGTTGTCCTACATCGAAATCGGCAAGCAAGAGGGTGCGGTGATTATCGCCGGAGGCGAGCGCG
CCGAACTGGGCGGCGACCTGTCCGGCGGTTACTACATGCAGCCGACGATCTTCACCGGCACCAACAACATGCGGATTTTC
CAGGAGGAGATCTTCGGGCCGGTGGTCGCCGTGACGTCCTTCACCGATTACGACGACGCGATCGGCATCGCCAACGACAC
CCTCTACGGCTTGGGTGCGGGTGTGTGGAGCCGCGACGGCAACACCGCCTATCGGGCCGGGCGGGACATCGCGGCCGGCC
GGGTGTGGGTTAACTGCTACCACCTCTACCCCGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGGGAG
GGCCACCAGATGATGCTGCAGCACTACCAGCACACCAAGAACCTGCTGGTGTCCTACTCGGATAAGGCGCTGGGGTTCTT
CTGA

Protein sequence :
MTVFSRPGSAGALMSYESQYRNFIGGQWVAPVHGRYFENPTPVTGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAE
RAAILNKIADRIDKNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAAAIRAQEGALSQIDEDTVAYHFHEPLGVVG
QIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT
GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLE
LAAIRTKAVRQGDPLDTETMLGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNMRIF
QEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAGRDIAAGRVWVNCYHLYPAHAAFGGYKQSGIGRE
GHQMMLQHYQHTKNLLVSYSDKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-129 61
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-135 59
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-135 59
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-135 59
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-134 59
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 7e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BN43_10497 YP_007286337.1 Putative aldehyde dehydrogenase VFG0082 Protein 4e-129 61