Gene Information

Name : clpC (BN43_90097)
Accession : YP_007289547.1
Strain : Mycobacterium canettii CIPT 140070008
Genome accession: NC_019965
Putative virulence/resistance : Virulence
Product : Putative ATP-dependent Clp protease ATP-binding subunit ClpC1
Function : -
COG functional category : -
COG ID : -
EC number : 3.4.-.-
Position : 4048444 - 4050990 bp
Length : 2547 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11271494, 12657046, 15525680, 15928073, 17611072, 8655000; Product type pf : putative factor

DNA sequence :
ATGTTCGAACGATTTACCGACCGTGCCCGCAGGGTCGTCGTCCTGGCGCAGGAAGAGGCCAGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATTCTTTTAGGCCTGATCCATGAAGGGGAAGGCGTCGCCGCCAAGTCACTGGAGTCGCTGGGGA
TCTCGCTGGAGGGTGTGCGCAGTCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGTCCGGGCACATCCCGTTT
ACCCCCCGCGCCAAGAAGGTCCTCGAGCTGAGCTTGCGTGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAACA
CATTTTGCTGGGCCTCATCCGGGAGGGTGAAGGCGTGGCCGCCCAGGTGCTGGTCAAGCTGGGCGCCGAGCTGACCCGGG
TGCGCCAGCAGGTGATCCAGCTGCTGTCGGGCTACCAGGGCAAGGAGGCCGCCGAAGCCGGCACCGGCGGCCGCGGGGGA
GAGTCCGGCTCCCCGTCTACGTCCTTGGTGCTCGACCAGTTCGGCCGCAACCTCACGGCGGCCGCAATGGAAGGCAAGCT
GGACCCGGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGTCCCGGCGCACCAAGAACAACCCGGTGC
TCATCGGCGAGCCCGGTGTGGGCAAGACCGCGGTCGTCGAAGGACTGGCGCAGGCCATCGTGCACGGCGAGGTGCCCGAG
ACGCTCAAGGACAAGCAGCTCTACACGCTGGATCTGGGATCGCTGGTGGCGGGTAGCCGCTACCGCGGTGACTTCGAGGA
ACGCCTCAAGAAGGTGCTCAAGGAGATCAACACCCGCGGTGACATCATCCTGTTTATCGACGAGCTGCACACCTTGGTCG
GGGCCGGCGCCGCCGAGGGCGCGATCGACGCCGCCTCGATCCTGAAACCGAAGCTCGCTCGCGGTGAACTGCAAACGATC
GGCGCCACCACGCTCGACGAATACCGTAAGTACATCGAGAAGGATGCCGCGCTGGAGCGCCGATTCCAGCCGGTGCAGGT
GGGTGAGCCGACGGTGGAGCACACCATCGAGATCCTCAAGGGCCTGCGGGACCGGTACGAGGCGCACCACCGGGTGTCGA
TCACCGATGCGGCGATGGTGGCCGCCGCGACCCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCCGACAAGGCGATC
GATCTGATCGACGAGGCGGGTGCTCGGATGCGGATTCGTCGCATGACCGCGCCGCCGGACCTACGCGAGTTCGATGAGAA
GATCGCCGAGGCTCGTCGGGAGAAGGAATCGGCTATCGACGCCCAGGACTTCGAGAAGGCCGCCAGCCTGCGTGACCGGG
AGAAGACATTGGTCGCACAGCGTGCTGAGCGCGAAAAGCAGTGGCGTTCAGGCGATCTTGACGTGGTCGCCGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTGGGCAACTGGACCGGTATCCCGGTGTTCAAGCTCACCGAGGCCGAGACCACCCGGCT
GTTGCGGATGGAAGAAGAGCTGCACAAGCGGATCATCGGGCAAGAGGACGCCGTCAAGGCCGTTTCCAAGGCCATCCGGC
GTACTCGGGCTGGGCTGAAAGACCCCAAGCGCCCGTCGGGCTCGTTTATCTTCGCCGGTCCGTCCGGTGTCGGTAAGACC
GAACTGTCCAAGGCGCTGGCCAACTTCTTGTTCGGTGACGACGACGCGCTCATTCAGATTGACATGGGTGAATTCCACGA
CCGGTTCACCGCGTCGCGGCTATTCGGCGCGCCGCCCGGATACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGAAGG
TGCGCCGCAAGCCGTTTTCGGTGGTGCTGTTCGACGAGATCGAGAAGGCGCATCAGGAGATCTACAACAGCCTGCTGCAG
GTGCTTGAGGATGGCCGGCTCACCGACGGGCAGGGCCGTACGGTGGACTTCAAGAACACCGTGCTGATCTTTACGTCCAA
TCTGGGCACCTCCGACATCTCCAAGCCGGTCGGTCTGGGCTTTTCCAAGGGCGGCGGTGAGAACGACTACGAGCGGATGA
AACAGAAGGTCAACGACGAGCTGAAGAAACACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC
CAGCTGACCCGCGAGGAGATCATCCGGATGGTCGACCTGATGATCAGCCGGGTCGCCGGCCAGCTCAAGAGCAAGGACAT
GGCGCTGGTGCTGACCGATGCAGCCAAGGCGCTGCTGGCCAAGCGTGGCTTCGACCCGGTGTTGGGGGCCCGCCCGTTGC
GGCGCACCATCCAGCGTGAGATCGAAGATCAGCTCTCGGAGAAGATCCTCTTCGAGGAGGTCGGGCCGGGTCAGGTGGTC
ACCGTCGACGTGGACAACTGGGACGGTGAAGGTCCCGGCGAGGACGCGGTGTTCACCTTCACCGGTACCCGCAAGCCTCC
GGCCGAGCCGGATCTGGCCAAGGCTGGAGCGCACAGCGCGGGCGGCCCGGAGCCGGCCGCGCGGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG
ESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKTLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTREEIIRMVDLMISRVAGQLKSKDMALVLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQVV
TVDVDNWDGEGPGEDAVFTFTGTRKPPAEPDLAKAGAHSAGGPEPAAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 81

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_007289547.1 Putative ATP-dependent Clp protease ATP-binding subunit ClpC1 VFG0079 Protein 0.0 60
clpC YP_007289547.1 Putative ATP-dependent Clp protease ATP-binding subunit ClpC1 VFG0080 Protein 7e-140 51