Gene Information

Name : dfrA (BN43_40448)
Accession : YP_007288708.1
Strain : Mycobacterium canettii CIPT 140070008
Genome accession: NC_019965
Putative virulence/resistance : Resistance
Product : Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)
Function : -
COG functional category : -
COG ID : -
EC number : 1.5.1.3
Position : 3116506 - 3116985 bp
Length : 480 bp
Strand : -
Note : Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 10623528, 9368362; Product type e : enzyme

DNA sequence :
ATGGTGGGGCTGATCTGGGCTCAAGCGACATCGGGTGTCATCGGCCGCGGCGGCGACATCCCCTGGCGCTTGCCCGAGGA
CCAGGCGCATTTCCGGGAGATCACCATGGGGCACACGATCGTGATGGGCCGGCGCACATGGGATTCGCTGCCGGCTAAAG
TCCGGCCGCTGCCCGGCCGGCGAAATGTCGTACTGAGCCGCCAAGCTGACTTTATGGCCAGCGGGGCTGAGGTTGTCGGT
TCACTCGAGGAGGCGCTGACCAGCCCGGAGACGTGGGTGATCGGAGGCGGACAAGTCTATGCGCTGGCGCTGCCGTACGC
GACCAGATGTGAGGTTACCGAGGTCGACATCGGCCTGCCGCGCGAAGCCGGTGACGCGCTGGCCCCCGTGCTGGACGAGA
CATGGCGGGGCGAGACGGGGGAGTGGCGCTTCAGCCGGTCCGGGTTGCGGTACCGGTTGTACAGCTACCACCGCTCATGA

Protein sequence :
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVG
SLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 5e-19 41