Gene Information

Name : tkt (BN43_30560)
Accession : YP_007287358.1
Strain : Mycobacterium canettii CIPT 140070008
Genome accession: NC_019965
Putative virulence/resistance : Unknown
Product : Transketolase Tkt (TK)
Function : -
COG functional category : -
COG ID : -
EC number : 2.2.1.1
Position : 1644495 - 1646597 bp
Length : 2103 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10537214, 11271494, 12657046, 15525680, 17443846; Product type e : enzyme

DNA sequence :
GTGACCACGCTCGAAGAGATCTCCGCGCTTACCCAACCGCGCCATCCCGGCGACTGGACCGAGATCGATTCGGCTGCCGT
CGACACCATCCGGGTCCTGGCCGCCGACGCCGTCCAAAAGGTCGGCAACGGTCATCCCGGAACGGCGATGAGCCTGGCCC
CGCTGGCTTACACGCTGTTTCAGCGGACAATGCGCCACGATCCCAGCGACACACACTGGCTGGGCCGCGACCGGTTCGTT
TTGTCGGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATCGA
GTCGTTGCGCACGTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACGCCCGGCGTTGAGATCACCACCGGCC
CGCTGGGCCAGGGACTGGCGTCGGCGGTTGGGATGGCGATGGCCTCGCGCTACGAACGCGGCCTGTTCGACCCGGACGCC
GAGCCGGGCGCCAGCCCCTTCGACCACCACATCTACGTCATCGCCTCCGACGGCGACATCGAAGAAGGGGTGACCTCGGA
AGCGTCGTCGCTGGCCGCCGTCCAGCAACTGGGCAACCTCATCGTGTTCTACGACCGCAACCAGATCTCGATCGAGGACG
ACACCAACATCGCGCTGTGTGAGGACACCACCGCGCGCTACCGCGCCTATGGCTGGCACGTGCAGGAGGTAGAGGGTGGT
GAGAACGTCGTCGCCATCGAGGAGGCCATCGCCAATGCGCAGGCCGTCCCCGACCGGCCCTCGTTCATCGCGCTGCGCAC
CGTCATCGGTTATCCGGCGCCGAACCTGATGGACACCGGCAAGGCGCACGGCGCGGCGCTGGGCGACGACGAGGTGGCCG
CCGTCAAGAAGATCCTCGGCTTCGATCCGGACAAGACGTTCCAGGTCCGCGAGGACGTCCTCACCCACACCCGAGGGCTG
GTGGCCCGCGGCAAACAGGCCCACGAACGCTGGCAACTCGAATTCGACGGGTGGGCGCGGCGTGAACCCGAGCGCAAGGC
GCTGCTGGACCGGCTGCTCGCGCAGAAGTTGCCCGACGGCTGGGACGCCGACCTGCCGCGCTGGGAACCGGGGTCCAAAG
CACTGGCCACCCGCGCGGCTTCCGGTGCGGTGCTGTCCGCGCTCGGACCGAAACTTCCCGAGCTGTGGGGGGGTTCGGCC
GACCTGGCCGGCAGCAACAACACCACCATCGCGGGCGTCGACTCCTTTGGCCCGCCCTCGATTTCCACCAAGGAGTACAC
CGCGCACTGGTATGGTCGCACCCTGCACTTCGGTGTTCGCGAGCACGCGATGGGTGCCATCCTGTCCGGCATCGTGCTGC
ACGGCCCCACGCGGGCTTACGGCGGCACCTTCCTGCAGTTCTCCGACTACATGCGCCCGGCGGTGCGGCTGGCGTCGCTG
ATGGACATCGACACCATCTATGTGTGGACGCATGATTCGATCGGGCTCGGCGAAGACGGTCCGACCCATCAACCGATCGA
GCACCTCTCGGCGCTGCGCGCGATCCCCCGGCTGTCGGTGGTGCGCCCGGCAGATGCCAACGAGACGGCCTACGCCTGGC
GCACGATCCTGGCCCGCGGCAACGGCAGCGGGCCGGTCGGGTTGATCCTGACCCGCCAAGGTGTGCCGGTATTGGACGGC
ACCGACGCCGAAGGGGTTGCTCGCGGCGGGTACGTGCTGCGCGACCCCAGTGGTCTGGAACCCGGCGAGGAACCCGACGT
CATTCTCATCGCCACCGGCTCGGAGGTACAGCTGGCCGTCGCGGCGCAGACGTTGTTGGCCGACAACGACATCCTCGCCC
GGGTGGTGTCGATGCCGTGCCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTG
TCGGCGCGGGTGGCCGTCGAAGCCGGCGTCGCGCAATGCTGGCACCGGCTGGTCGGCGACACGGGCGAGATCGTCTCGAT
CGAGCACTACGGCGAATCCGCGGACCACAAGACCTTATTCCGCGAGTACGGCTTCACCGCCGAGGCCGTGGCCGCCGCCG
CCGAACGAGCGCTGGATAACTGA

Protein sequence :
MTTLEEISALTQPRHPGDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFV
LSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA
EPGASPFDHHIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTTARYRAYGWHVQEVEGG
ENVVAIEEAIANAQAVPDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKILGFDPDKTFQVREDVLTHTRGL
VARGKQAHERWQLEFDGWARREPERKALLDRLLAQKLPDGWDADLPRWEPGSKALATRAASGAVLSALGPKLPELWGGSA
DLAGSNNTTIAGVDSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLASL
MDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARGNGSGPVGLILTRQGVPVLDG
TDAEGVARGGYVLRDPSGLEPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTV
SARVAVEAGVAQCWHRLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 5e-116 43
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-115 42