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Name : metB (BN43_30133) Accession : YP_007286983.1 Strain : Mycobacterium canettii CIPT 140070008 Genome accession: NC_019965 Putative virulence/resistance : Resistance Product : Cystathionine gamma-synthase, PLP-dependent Function : - COG functional category : - COG ID : - EC number : 2.5.1.48 Position : 1216505 - 1217671 bp Length : 1167 bp Strand : + Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3307782, 6361020, 87326410, 90148970, 9843488; Product type e : enzyme DNA sequence : ATGAGCGAAGACCGCACGGGACACCAGGGAATCAGCGGACCGGCCACCCGCGCCATCCACGCTGGCTACCGCCCGGATCC GGCGACCGGGGCGGTGAACGTGCCGATCTACGCCAGCAGCACCTTCGCCCAAGACGGCGTCGGCGGTCTGCGTGGCGGTT TCGAATATGCACGCACCGGCAACCCCACCCGGGCCGCATTGGAGGCCTCGCTGGCGGCAGTCGAGGAGGGTGCTTTCGCG CGGGCATTCAGTTCCGGGATGGCCGCGACCGACTGCGCCCTGCGGGCGATGTTACGGCCCGGAGACCACGTCGTCATTCC CGATGACGCCTACGGCGGCACATTCCGGTTGATAGACAAGGTGTTCACCCGGTGGGATGTCCAGTACACGCCGGTGCGGC TTGCCGATCTGGATGCGGTGGGTGCCGCGATTACTCCACGCACCCGGCTGATTTGGGTGGAGACGCCCACCAATCCGCTA CTGTCGATCGCCGATATCACGGCCATTGCCGAGCTGGGCACAGACAGATCGGCAAAAGTATTGGTGGACAATACCTTTGC CTCACCCGCGTTGCAGCAGCCGTTGCGGCTGGGCGCCGATGTGGTGTTGCACTCGACTACCAAGTACATCGGCGGCCATT CCGACGTGGTGGGAGGTGCGCTGGTCACCAACGACGAAGAGCTGGACGAGGAGTTCGCTTTCTTGCAGAACGGCGCCGGC GCGGTGCCCGGACCATTCGACGCCTACCTGACCATGCGCGGCCTGAAGACCTTGGTGCTGCGGATGCAGCGGCACAGTGA AAATGCCTGTGCGGTAGCGGAATTCCTCGCTGATCATCCGTCGGTGAGTTCTGTGTTGTATCCGGGTTTGCCCAGTCATC CCGGGCATGAGATTGCCGCGCGACAGATGCGCGGCTTCGGCGGCATGGTTTCGGTGCGGATGCGGGCCGGTCGGCGTGCG GCGCAGGACCTGTGTGCCAAGACCCGCGTCTTCATCCTGGCCGAGTCGCTGGGTGGGGTGGAGTCGCTGATCGAACATCC CAGCGCCATGACCCATGCGTCGACGGCCGGTTCGCAATTGGAGGTGCCCGACGATCTGGTGCGGCTTTCGGTCGGTATCG AAGACATTGCCGACCTGCTCGGCGATCTCGAACAGGCCCTGGGTTAA Protein sequence : MSEDRTGHQGISGPATRAIHAGYRPDPATGAVNVPIYASSTFAQDGVGGLRGGFEYARTGNPTRAALEASLAAVEEGAFA RAFSSGMAATDCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTRWDVQYTPVRLADLDAVGAAITPRTRLIWVETPTNPL LSIADITAIAELGTDRSAKVLVDNTFASPALQQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAG AVPGPFDAYLTMRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAARQMRGFGGMVSVRMRAGRRA AQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQLEVPDDLVRLSVGIEDIADLLGDLEQALG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-71 | 45 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-72 | 45 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 7e-56 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| metB | YP_007286983.1 | Cystathionine gamma-synthase, PLP-dependent | BAC0207 | Protein | 1e-60 | 43 |
