Gene Information

Name : Natpe_3319 (Natpe_3319)
Accession : YP_007282010.1
Strain : Natrinema pellirubrum DSM 15624
Genome accession: NC_019962
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3242621 - 3244378 bp
Length : 1758 bp
Strand : -
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGAGAAACGCGAAGATCGTCTGTACGCTGGGACCGGCGTCGAACGACCGGGAAACGATCCGGGAGTTGGCCGAGGCGGG
GATGTCGGTCGCACGGCTGAACGCGAGCCACGGAAGCCGCGAGGACCGCGCCGCATTGATCGACCGGGTCCGCGCGGTCG
ACGAGGAGCGCACCGAGCCCGTCGCGGTCATGCTCGACATGCAGGGCCCCGAGATCCGGACCGCGCCCCTGCCCGAGGGG
GAGACAGTGACGCTCGAGACGGGCTCGGAGATCCGCTTCGTCGAGGGCGGGACGGCGACGCCGGAGACCGTCGGGCTCTC
GCTGTCGATCGACGCCGTTGAGCCCGGCGATCGGATCCTGCTCGACGACGGGTTGATCGAGACGACGGTCCTCGAAACCG
AGGGCGAGGGCGTCCGCGCCCGCGTCGATACCGGCGGCGACCTCGGCGGCCGCAAGGGGGTCAACGTCCCCGGCGTCGAA
CTCGGTCTCGACGTCGTTACCGAGTCTGATCGGCGGGATCTCGAGCTGGCCGCCGAAAAGGAGGTCGACTTCGTCGCCGC
GAGTTTCGTCCGGGACGCCGACGACGTCTACGAGGTCGACGAGGTACTCGAGGCGGCCGGCGCTGACATTCCGGTCATCG
CGAAGATCGAGCGAGCGGGCGCGGTCGAAAACTTGGACGAGATCATCGACGCCGCCTACGGCGTGATGGTCGCCCGCGGC
GACCTCGGCGTCGAGTGTCCGATGGAGGACGTCCCGATGATCCAAAAGCGGATCATCCGGAAGTGCCGCGAGGCGGGGCG
ACCGGTCATCACGGCGACGGAGATGCTCGACTCGATGGTGACGGCTCGCCGGCCCACCCGTGCGGAGGCCTCCGACGTCG
CCAACGCCGTCCTCGACGGCACCGACGCGGTCATGCTGTCGGCCGAGACCGCGATCGGTGACCACCCTGTCGCCGTCGTC
GACGCGATGGACAGCATCGTCCGCGAAGTCGAGGGCTCCGTGGAACACGCCGAACTGTTCGAGCAGCGGGTCCCGGCCGC
GGGCGAGGCGCGGACGGACGCGCTGGCTCGTTCGGCCCGCTTTCTGGCCCGGGATATCGACGCGGACGCGGTCGTCGCCG
CGACCGAGTCCGGCTACACCGCACTCAAGACGGCGAAGTACCGCCCGGGCGTACCCGTCGTCGCCTCGACGCCGAGTCAG
GCGGTGCGTCGCCAGCTCGCGCTGACCTGGGGCGTGACGCCGCTGTATGCCTCCGTCTCGGATCAGGGTGCCGACGCCGT
CGTCGAGAAGGCCGTTCAGGCCGCGTTAGACGCCGGCATCGCCGAAAGCGGGGACACCGTCGTCGTCCTCTGTGGCATGA
TGACCGAACTCGAGGGGGCGAACACGACGAACATGCTGAAGGTCCACGTCGCGGCCGACGCCCTGACGACCGGCCAGGTG
GTCGTCGAGGGCCGGGCGACCGGGCCGATCGTTCACGCCACCGACGGCGATCTCTCGGGAGTCCCCGAGGGAGCGATCCT
TGCGCTGTCGGCCGACTTCGACGCGGAATTCTCGAGCGAGACGGATCGAATCGGCGGGATCGTCAACGCCCAGCGGGGGA
TGACCGGTTATCCGGCGATGATCGCGCGCGAACTGGGCGTGCCGATGATCAGCGACGCGGACGTCGAGACGCTGTCGGCC
GGCGAGACGGTCACCGTCGACGCGGAACGCGGCGTCGTCTACGGCGGCGACATCGGGGGCCGTCCCGAGCGCCCCTGA

Protein sequence :
MRNAKIVCTLGPASNDRETIRELAEAGMSVARLNASHGSREDRAALIDRVRAVDEERTEPVAVMLDMQGPEIRTAPLPEG
ETVTLETGSEIRFVEGGTATPETVGLSLSIDAVEPGDRILLDDGLIETTVLETEGEGVRARVDTGGDLGGRKGVNVPGVE
LGLDVVTESDRRDLELAAEKEVDFVAASFVRDADDVYEVDEVLEAAGADIPVIAKIERAGAVENLDEIIDAAYGVMVARG
DLGVECPMEDVPMIQKRIIRKCREAGRPVITATEMLDSMVTARRPTRAEASDVANAVLDGTDAVMLSAETAIGDHPVAVV
DAMDSIVREVEGSVEHAELFEQRVPAAGEARTDALARSARFLARDIDADAVVAATESGYTALKTAKYRPGVPVVASTPSQ
AVRRQLALTWGVTPLYASVSDQGADAVVEKAVQAALDAGIAESGDTVVVLCGMMTELEGANTTNMLKVHVAADALTTGQV
VVEGRATGPIVHATDGDLSGVPEGAILALSADFDAEFSSETDRIGGIVNAQRGMTGYPAMIARELGVPMISDADVETLSA
GETVTVDAERGVVYGGDIGGRPERP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-63 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-63 41
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 4e-46 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Natpe_3319 YP_007282010.1 pyruvate kinase VFG0479 Protein 7e-64 41