Gene Information

Name : Natpe_2627 (Natpe_2627)
Accession : YP_007281338.1
Strain : Natrinema pellirubrum DSM 15624
Genome accession: NC_019962
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2565061 - 2567523 bp
Length : 2463 bp
Strand : +
Note : PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC

DNA sequence :
ATGAGTACTGAATCGGACGCGACGCGGGAAACGGACGGGGGCGGGCAGCGACGGGAGCTGACCGCCCGACTCGCCGTTCC
CGAGATGGATTGCCCGTCCTGTGCGGGGAAAGTCGACAAGAGCCTCGGACGCGTCGACGGCGTGGTCGACGTCGATCTCA
ATCCGACCACCGGGACGGCCACGGTCGCGTACGACCGCGATCGAACCAGCGAGGCCGACGTGGTCGCGGCGATCGAAGGG
GCCGGCTACGAGGTCACCGGCGGAACGGCCGACGACGGGGCGACGGAATCGGCCTCGAGCGGCGACGGCGTCGGCATCGC
GCCGCCCTCGGAGGTCTGGACGAGTCCGCGCGCGAAGAAGACGTGGCTCGGTGCGGTCTTCGTCGTCCTCGGGCTGGGCT
TCGAGTTCCTCCTGACGGGCGGCAACGTCGCGGTGGCGAGCGTCCTCGAGTATCCCCTCCACGTCGCGGATCTGCTCTTT
CTCGGGGCGGTCGCGGTCAGCGGCATCCCCGTCGTCCGGAGCGGCTACTACTCCGCGAGAAACCGGAGCCTCGACATCGA
CCTCCTGATGGGGACGGCGATCATCGCCGCGACCGGCATCGGCTACTTCGTCGAAGCTGCGACGCTCGCGGTGCTGTTCA
GCATCGCCGAACTGCTCGAGGACTACGCGATGGATCGGGCGCGGGACTCCCTGCGCGAACTGATGGAACTCTCGCCGGAC
GAGGCCACAGTCATGCGCGACGGCGAGGAGGTGACCGTCGACGCGGACGACGTGGCGGTCGGCGAGACCGTCGTCGTCCG
GCCCGGGGACAAGATCCCGCTCGACGGGACGGTCCGTGAGGGCGAGAGCGCGGTCGACGAGTCGCCGATCACCGGCGAGA
GCGTCCCCGTGGACAAATCGACCGGCGACGAGGTGTACGCCGGAACCATCACCGAGGACGGCTACCTCGAGGTCGAGGTC
ACTTCGACGGCGGGCGATTCGACGCTCTCGCGGATCATCGAGATGGTCCAGGGGGCACAGGCCGACAAGACGGAAACCGA
GCAGTTCGTCGACCGGTTCGCGGGCTATTACACGCCCGTCGTGGTCGTCCTGGCGATCCTGACCGCCGCCGTGCCGCCGC
TTCTCATCGGCGACACCGTCACTGCGGGGATCGCCGGCTACGAGATCGCGTTCGCCGGCGACTGGGGGACGTGGTTCGTC
CGCGGGCTCACGCTGCTTGTGATCGCCTGCCCCTGTGCGTTCGTCATCTCGACGCCCGTCTCGGTCGTCTCGGGGGTCAC
CAGCGCCGCGCGAAACGGCGTCCTGATCAAGGGCGGCACGTATCTCGAGGCGATGGGCGAGGTCGACGCCGTCGCCGTCG
ACAAGACCGGTACGCTCACGAAAGGCGAACTCGCCGTGACCGACGTTGTGCCCTGCGCGGCGCCCAGCGCCGCGAACGAG
GCGAGCGGTGAAACCGCGAGCCAGGCCGACGGAGCCGACGAGGCGACGCTGCTTCGCTATGCCGCCGGACTGGAGCAACG
CAGCGAACACCCCATCGCCGCGGCGATCCTCGCGCGGGCCGACGAAGCGGACGTGGGCGACCTCCCCGAGCCGACGGGGT
TCGAGAGCCTCACCGGCAGGGGGATCCGCGGGGAGATCGAGGGCGAGACCTACTACGCGGGCAAGCCCGCGCTGTTCGAG
GAACTGGGCTTCGATCTCTCGCGGACCCGCGCGGACGACTCCTCGGGCCCGCGGACTGACGGCGGGGCCGCAGCCGAGAG
TGCGCTCGCAGCCGACGAGGGAGGCTTCACCGGGGACACGCTCGCCGCGCTCGAGCGGGAGGGGAAGACGGTCGTCCTCG
TCGGGACGGAGACCGACCTGCTCGGCGCGGTCGCGATCGCCGACGAGGTCCGGCCCGCGTCCAGACGGGCGGTCGAACGG
CTCCACGACCTCGGCGTCGAGCGCGTCGTCATGCTGACCGGGGACAACGAGGGCACGGCGCGGGCGATCGCCGAGCAGGT
CGGCGTTGACGAGTACCGTGCCGAACTCCTCCCCGACGAGAAGGTCGACGCCGTGGCGGCCCTCCAGGAGCAGTACGGCG
ACGTGGCGATGGTCGGCGACGGCATCAACGACGCGCCCGCGCTTGCGACCGCTGAGGTCGGCATCGCGATGGGCGCGGCC
GGTACCGACACCGCCCTCGAGACGGCGGATATCGCGCTGATGGGCGACGACATCGGGCGGCTACCGTACCTGTACGACCT
CTCGCACACGGCAAACGGCGTCATTCGACAGAACGTCTGGGCGAGCCTCGCCGTGAAGGCCCTACTCGCCGTCGGCGTGC
CGCTGGGGCTGGTCAGCGTCGCGGTGGCGGTCGTCGTCGGCGACATGGGGATGAGCCTCGGCGTCACCGGCAACGCGATG
CGGCTCGCGAACGTCGAGCCCGACGCACTCACGACCTCCGAGGGCGGCCCCGACGCTCCATAA

Protein sequence :
MSTESDATRETDGGGQRRELTARLAVPEMDCPSCAGKVDKSLGRVDGVVDVDLNPTTGTATVAYDRDRTSEADVVAAIEG
AGYEVTGGTADDGATESASSGDGVGIAPPSEVWTSPRAKKTWLGAVFVVLGLGFEFLLTGGNVAVASVLEYPLHVADLLF
LGAVAVSGIPVVRSGYYSARNRSLDIDLLMGTAIIAATGIGYFVEAATLAVLFSIAELLEDYAMDRARDSLRELMELSPD
EATVMRDGEEVTVDADDVAVGETVVVRPGDKIPLDGTVREGESAVDESPITGESVPVDKSTGDEVYAGTITEDGYLEVEV
TSTAGDSTLSRIIEMVQGAQADKTETEQFVDRFAGYYTPVVVVLAILTAAVPPLLIGDTVTAGIAGYEIAFAGDWGTWFV
RGLTLLVIACPCAFVISTPVSVVSGVTSAARNGVLIKGGTYLEAMGEVDAVAVDKTGTLTKGELAVTDVVPCAAPSAANE
ASGETASQADGADEATLLRYAAGLEQRSEHPIAAAILARADEADVGDLPEPTGFESLTGRGIRGEIEGETYYAGKPALFE
ELGFDLSRTRADDSSGPRTDGGAAAESALAADEGGFTGDTLAALEREGKTVVLVGTETDLLGAVAIADEVRPASRRAVER
LHDLGVERVVMLTGDNEGTARAIAEQVGVDEYRAELLPDEKVDAVAALQEQYGDVAMVGDGINDAPALATAEVGIAMGAA
GTDTALETADIALMGDDIGRLPYLYDLSHTANGVIRQNVWASLAVKALLAVGVPLGLVSVAVAVVVGDMGMSLGVTGNAM
RLANVEPDALTTSEGGPDAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 7e-97 44
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-96 43
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-96 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Natpe_2627 YP_007281338.1 heavy metal translocating P-type ATPase BAC0298 Protein 6e-78 43