Gene Information

Name : thiC (BN45_10463)
Accession : YP_007267059.1
Strain : Mycobacterium canettii CIPT 140070017
Genome accession: NC_019952
Putative virulence/resistance : Unknown
Product : Putative thiamine biosynthesis protein ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 515178 - 516821 bp
Length : 1644 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12657046, 15525680; Product type pe : putative enzyme

DNA sequence :
ATGACCATCACCGTTGAACCGTCGGTGACCACGGGTCCCATCGCGGGCAGCAGCAAGGCCTACCGTGAAATCGAGGCTCC
CGGCAGCGGAGCTACTCTCCAAGTCCCGTTTCGACGGGTGCACTTGTCCACCGGAGACCACTTCGACCTCTACGACACCT
CCGGGCCCTACACCGAGGCGGACGCGGTGATCGACCTGACCGCCGGGCTGCCACCCCGGCCCGGGGTGGTCCGCGATCGG
GGCACCCAGCTGCAGCGGGCCCGCGCCGGGGAGATCACCGCCGAGATGGCGTTCGTCGCCGCCCGCGAGGGCCTGCCCGC
CGAGCTGGTGCGCGACGAGGTCGCCCGCGGGCGGGCGGTGATCCCGGCCAACCACCACCATCCCGAGAGCGAGCCGATGA
TCATCGGCAAGGCGTTCGCGGTGAAAGTCAACGCCAACATCGGCAACTCGGCGGTGACGAGCTCGATCGCCGAGGAGGTC
GACAAGATGGTGTGGGCCACCCGCTGGGGGGCCGACACCATCATGGACCTGTCCACCGGCAAGAACATCCACGAAACCCG
CGAGTGGATCCTGCGCAATTCTCCGGTGCCGGTCGGCACCGTGCCGATCTATCAGGCGTTGGAGAAAGTCAAGGGCGATC
CGACCGAGCTGACCTGGGAGATCTACCGCGACACCGTGATCGAGCAGTGTGAGCAAGGCGTGGACTACATGACGGTGCAC
GCCGGGGTGCTGCTGCGGTATGTGCCGTTGACCGCCAAGCGGGTCACCGGCATCGTCAGCCGCGGCGGCTCGATCATGGC
GGCCTGGTGCCTGGCACATCATCGGGAGTCGTTCCTGTACACCAACTTTGAGGAGCTCTGCGATATTTTCGCGCGCTACG
ACGTCACCTTCTCACTCGGTGACGGGCTGCGACCAGGGTCGATCGCCGACGCCAACGACGCCGCCCAGTTCGCCGAGCTG
CGCACCCTGGGCGAGCTCACCAAGATCGCCAAAGCCCATGGTGCACAGGTGATGATCGAGGGGCCGGGCCATATCCCAAT
GCACAAGATCGTCGAGAATGTGCGGCTGGAAGAGGAACTGTGTGAGGAGGCCCCGTTCTACACGCTGGGTCCGCTGGCCA
CCGACATCGCGCCGGCCTACGACCACATCACCTCGGCGATCGGTGCGGCCATCATCGCCCAAGCCGGTACCGCGATGCTG
TGCTACGTCACCCCCAAGGAGCACCTCGGGTTGCCGGACCGCAAGGACGTCAAGGACGGGGTGATCGCCTACAAGATCGC
CGCGCATGCGGCCGATTTGGCCAAGGGTCATCCGCGCGCCCAGGAGCGCGACGACGCTTTGAGCACGGCGCGTTTCGAGT
TCCGCTGGAACGACCAGTTCGCACTGTCGCTGGATCCCGACACCGCACGGGAATTCCACGACGAAACCCTGCCGGCGGAG
CCGGCCAAGACCGCGCACTTCTGCTCGATGTGCGGACCGAAGTTCTGCTCCATGCGCATCACCCAGGACGTCCGTGAGTA
CGCCGCCGAACACGGGCTTGAGACCGAAGAGGACATCGAAGCCGTGCTCGCCGCCGGAATGGCCGAAAAGTCACGTGAAT
TCGCAGAGCACGGCAATCGGGTGTATCTCCCGATAACCCAGTGA

Protein sequence :
MTITVEPSVTTGPIAGSSKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTEADAVIDLTAGLPPRPGVVRDR
GTQLQRARAGEITAEMAFVAAREGLPAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEV
DKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAEL
RTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAML
CYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEEDIEAVLAAGMAEKSREFAEHGNRVYLPITQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-154 68
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-154 68
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-148 65