Gene Information

Name : dfrA (BN45_51147)
Accession : YP_007269450.1
Strain : Mycobacterium canettii CIPT 140070017
Genome accession: NC_019952
Putative virulence/resistance : Resistance
Product : Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)
Function : -
COG functional category : -
COG ID : -
EC number : 1.5.1.3
Position : 3163075 - 3163554 bp
Length : 480 bp
Strand : -
Note : Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 10623528, 9368362; Product type e : enzyme

DNA sequence :
ATGGTGGGGCTGATCTGGGCTCAAGCGACATCGGGTGTCATCGGCCGCGGCGGCGACATTCCCTGGCGCTTGCCCGAGGA
CCAGGCGCATTTCCGGGAGATCACCATGGGGCACACGATCGTGATGGGCCGGCGCACCTGGGATTCGCTGCCGGCTAAAG
TCCGGCCGCTGCCCGGCCGGCGAAATGTCGTACTGAGCCGCCAAGCTGACTTTATGGCCAGCGGGGCTGAGGTTGTCGGT
TCACTCGAGGAGGCGCTGACCAGCCCGGAGACATGGGTGATCGGAGGCGGACAGGTCTATGCGCTGGCGCTGCCGTACGC
GACCAGATGTGAGGTTACCGAGGTCGACATCGGCCTGCCGCGCGAAGCCGGTGACGCGCTGGCCCCCGTGCTGGACGAGA
CATGGCGGGGCGAGACGGGGGAGTGGCGCTTCAGCCGGTCCGGGCTGCGGTACCGGTTGTACAGCTACCACCGCTCATGA

Protein sequence :
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVG
SLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 5e-19 41