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Name : hsdM (BN45_51140) Accession : YP_007269443.1 Strain : Mycobacterium canettii CIPT 140070017 Genome accession: NC_019952 Putative virulence/resistance : Unknown Product : Putative type I restriction/modification system DNA methylase HsdM (M protein) (DNA methyltransferase) Function : - COG functional category : - COG ID : - EC number : 2.1.1.- Position : 3158415 - 3160037 bp Length : 1623 bp Strand : - Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12657046, 15525680; Product type pe : putative enzyme DNA sequence : ATGCCGCCGAGGAAGAAGCAGGCGCCGCAGGCACCGTCGACGATGAAGGAGCTCAAAGACACGCTCTGGAAGGCCGCCGA CAAGCTGCGCGGGTCGCTGTCGGCCAGCCAATACAAGGACGTGATCCTGGGCCTGGTGTTCCTCAAGTACGTGTCCGACG CCTATAACGAACGTCGCGAGGCGATCCGTGCCGAGTTGGCGGCCGACGGGATGGACGAGTCGCAGATAGAGGACCTGATC GACGATCCCGGGGAGTACCAGGGTTACGGGGTGTTCGTGGTGCCGCCTAGTGCGCGGTGGAAGTTCTTGGCGGAGAACGC AAAAGGCAAGCCGGCCGTTGGTGGTGAGTCGGCGAAGAACATCGGTCAGCTGATCGACGAGGCGATGGACGCCGTGATGA AGGCCAATCCAACACTCGGTGGGACGCTGCCGCGGCTGTACAACAAGGACAACATCGATCAGCGCCGGCTCGGTGAGCTG ATCGACTTGTTCAACAGTGCGCGATTCAGCCGGCAGGGTGCGCACCGGGCCCGGGATCTGATGGGGGAGGTCTACGAGTA CTTCCTCGGGAATTTCGCTCGCGCGGAAGGGAAGCGGGGTGGCGAGTTCTTTACCCCGCCCAGCGTGGTCAAGGTGATCG TGGAGGTGCTGGAGCCGTCAAGTGGGCGGGTGTATGACCCGTGCTGCGGTTCCGGAGGCATGTTTGTGCAGACCGAAAAG TTCATCTACGAACACGACGGTGATCCGAAGAATGTGGTGATCTATGGCCAGGAAAGCATTGAGGAGACCTGGCGGATGGC GAAGATGAACCTTGCCATCCACGGCATCGACAACAAGGGGCTCGGCGCCCGATGGGGTGATACCTTCGCCCGCGACCAGC ATCCGGACGTGCGGATGGACTACGTGATGGCCAATCCGCCGTTCAACATTAAAGACTGGGCCCGCAACGAGGAAGACCCA CGCTGGCGCTTCGGGGTTCCGCCCGCCAACAACGCCAACTACGCATGGATTCAGCACATCCTGTACAAGTTGGCGCCGGG GGGTAGGGCGGGTGTGGTGATGGCCAACGGGTCGATGTCGTCGAACTCCAACGGCGAGGGTGATATTCGGGCGCAGATCG TAGAGGCGGATGTGGTCTCCTGCATGGTCGCGTTACCCACCCAGCTATTCCGCAGCACCGGAATCCCGGTGTGCCTGTGG TTCTTCGCCAAGGACAAGGCGGCAGGTAAGCAGGGGTCTATCGACCGGTGCGGGCAGGTGCTGTTCATCGATGGTCGCGA ACTGGGCTACATGGTGGACCGGGCCGAGCGGGCGCTGACCAACGAGGAGATCGTCCGCATCGGTGACACCTTCCACGCGT GGCGCGGGTCGAAATCGGCGGCTGCGAAGGGCATCACCTACGAGGATGTTCCGGGATTCTGCAAGTCCGCAACGTTGGCG GAGATCAAGGCGGCCGACTACGCGTTGACTCCTGGGCGGTATGTGGGGGCGCCCGAGGTAGAGGACGACGGTGAGCCGAT CGACCAGAAGATCGCACGGCTGACGAAGGAGCTACTGGCTGCGTTCGACGAGTCGGCGAGGCTGGAAAGGGTCGTGCGGG AGCAACTGGGGCGGCTTAGATGA Protein sequence : MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYNERREAIRAELAADGMDESQIEDLI DDPGEYQGYGVFVVPPSARWKFLAENAKGKPAVGGESAKNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGEL IDLFNSARFSRQGAHRARDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK FIYEHDGDPKNVVIYGQESIEETWRMAKMNLAIHGIDNKGLGARWGDTFARDQHPDVRMDYVMANPPFNIKDWARNEEDP RWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVEADVVSCMVALPTQLFRSTGIPVCLW FFAKDKAAGKQGSIDRCGQVLFIDGRELGYMVDRAERALTNEEIVRIGDTFHAWRGSKSAAAKGITYEDVPGFCKSATLA EIKAADYALTPGRYVGAPEVEDDGEPIDQKIARLTKELLAAFDESARLERVVREQLGRLR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdM | YP_251979.1 | type I restriction-modification system DNA methylase | Not tested | SCCmec | Protein | 3e-122 | 49 |
| hsdM | BAH57701.1 | type I restriction-modification system DNA methylase | Not tested | Type-VII SCCmec | Protein | 6e-123 | 49 |
| hsdM | BAD24842.1 | HsdM protein | Not tested | Type-V SCCmec | Protein | 6e-122 | 48 |
| api49 | CAF28523.1 | putative HsdM-like N-methyl transferase | Not tested | YAPI | Protein | 4e-109 | 45 |
