Gene Information

Name : blaC (BN45_50375)
Accession : YP_007268754.1
Strain : Mycobacterium canettii CIPT 140070017
Genome accession: NC_019952
Putative virulence/resistance : Resistance
Product : Class A beta-lactamase BlaC
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.2.6
Position : 2416269 - 2417192 bp
Length : 924 bp
Strand : -
Note : Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12657046, 15525680, 17443846, 9624479; Product type e : enzyme

DNA sequence :
ATGCGCAACAGAGGATTCGGTCGTCGCGAACTGCTGGTGGCAATGGCAATGCTGGTTTCCGTGACGGGGTGTGCACGGCA
TGCGAGCGGGGCCCGTCCGGCATCGACAACCTTGCCGGCCGGACCGGATCTGGCGGATCGCTTCGCCGAGCTGGAGCGCA
GATACGATGCCCGGCTTGGGGTGTATGTGCCCGCCACCGGCACCACCGCCGCGATCGAATACCGCGCCGATGAGCGGTTC
GCATTCTGCTCCACGTTCAAGGCGCCGCTCGTGGCGGCGGTGCTGCACCAAAACCCGCTCACGCATCTGGACAAACTGAT
CACCTACACCAGTGACGACATTCGGTCGATCTCCCCGGTGGCCCAACAACACGTTCAGACCGGGATGACGATCGGGCAGC
TTTGCGATGCGGCGATACGCTATAGCGACGGCACCGCCGCCAACCTGTTGCTGGCCGATCTTGGCGGTCCCGGGGGCGGC
ACCGCGGCATTTACCGGCTACCTCCGCAGCTTGGGTGACACCGTGAGCCGGTTGGACGCCGAGGAACCGGAGTTGAACCG
CGATCCGCCCGGGGACGAACGGGATACCACAACACCGCACGCCATCGCCCTGGTGTTGCAGCAGCTTGTTCTCGGCAACG
CGTTGCCGCCCGACAAGCGGGCACTGCTCACCGATTGGATGGCGCGCAACACCACCGGAGCCAAGCGGATCCGAGCGGGC
TTTCCCGCCGATTGGAAGGTGATCGACAAGACCGGGACCGGTGACTACGGACGAGCAAACGACATCGCGGTCGTATGGTC
ACCGACCGGCGTGCCCTACGTGGTGGCCGTCATGTCCGATCGTGCCGGCGGCGGGTATGACGCCGAGCCCCGTGAGGCGC
TGCTCGCCGAGGCGGCGACGTGCGTTGCCGGTGTGCTTGCATAG

Protein sequence :
MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGPDLADRFAELERRYDARLGVYVPATGTTAAIEYRADERF
AFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGG
TAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAG
FPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAATCVAGVLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 1e-36 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
blaC YP_007268754.1 Class A beta-lactamase BlaC EU729727.1.gene1.p1 Protein 2e-39 50
blaC YP_007268754.1 Class A beta-lactamase BlaC AY034847.1.gene1.p01 Protein 1e-39 50
blaC YP_007268754.1 Class A beta-lactamase BlaC EU555534.1.gene1.p01 Protein 5e-40 50
blaC YP_007268754.1 Class A beta-lactamase BlaC AF297554.1.gene1.p1 Protein 3e-39 50
blaC YP_007268754.1 Class A beta-lactamase BlaC HQ641421.1.gene1.p01 Protein 2e-39 50
blaC YP_007268754.1 Class A beta-lactamase BlaC AF395881.gene.p01 Protein 1e-39 50
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ234412.1.gene1.p01 Protein 6e-40 50
blaC YP_007268754.1 Class A beta-lactamase BlaC HM066995.1.gene1.p01 Protein 3e-39 50
blaC YP_007268754.1 Class A beta-lactamase BlaC GQ140348.1.gene1.p01 Protein 2e-39 50
blaC YP_007268754.1 Class A beta-lactamase BlaC AB284167.2.gene1.p01 Protein 1e-38 49
blaC YP_007268754.1 Class A beta-lactamase BlaC AM982522.2.gene1.p01 Protein 1e-36 48
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ907381.1.gene1.p01 Protein 1e-38 48
blaC YP_007268754.1 Class A beta-lactamase BlaC EF418608.1.gene1.p01 Protein 2e-38 48
blaC YP_007268754.1 Class A beta-lactamase BlaC AY822595.1.gene1.p01 Protein 1e-38 48
blaC YP_007268754.1 Class A beta-lactamase BlaC EF581888.1.gene1.p01 Protein 3e-38 48
blaC YP_007268754.1 Class A beta-lactamase BlaC EF374097.1.gene1.p01 Protein 6e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AJ567481.1.gene1.p01 Protein 9e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC GQ149243.1.gene1.p01 Protein 2e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC HM776707.1.gene1.p1 Protein 5e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC GU127598.1.gene1.p1 Protein 7e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AJ005045.gene.p01 Protein 3e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC X92507.1.gene1.p01 Protein 6e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC U95364.1.gene1.p01 Protein 3e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ408762.1.gene1.p1 Protein 5e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC GQ149244.1.gene1.p01 Protein 5e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AJ416344.1.gene1.p01 Protein 7e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ102702.1.gene1.p1 Protein 1e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ125241.gene.p01 Protein 6e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY157676.1.gene1.p01 Protein 1e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AF518567.2.gene4.p01 Protein 3e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AM411407.1.gene1.p01 Protein 8e-39 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY954516.1.gene1.p1 Protein 3e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ971899.1.gene1.p1 Protein 1e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ023162.1.gene1.p1 Protein 2e-35 47
blaC YP_007268754.1 Class A beta-lactamase BlaC GQ870432.1.gene1.p1 Protein 2e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC HM167760.1.gene1.p01 Protein 3e-36 47
blaC YP_007268754.1 Class A beta-lactamase BlaC JF966749.1.gene1.p01 Protein 1e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC HQ913565.1.gene1.p01 Protein 7e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AF305837.gene.p01 Protein 3e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC JF274243.1.gene1.p01 Protein 4e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC GQ351346.1.gene1.p01 Protein 2e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ214366.1.gene1.p1 Protein 6e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY847143.1.gene1.p01 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC EU402393.1.gene1.p1 Protein 3e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC HQ833652.1.gene1.p01 Protein 4e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY847146.1.gene1.p01 Protein 7e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC EU136031.3.gene1.p3 Protein 5e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC JF274246.1.gene1.p01 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY847145.1.gene1.p01 Protein 2e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AF325133.1.gene1.p1 Protein 4e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ214368.1.gene1.p1 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY143430.1.gene1.p01 Protein 5e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY156923.1.gene1.p01 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY238472.1.gene1.p01 Protein 6e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC HM803271.1.gene1.p01 Protein 2e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ214367.1.gene1.p1 Protein 4e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC JF274247.1.gene1.p01 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY033516.1.gene2.p01 Protein 4e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC HQ833651.1.gene1.p01 Protein 6e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AF174129.3.gene9.p01 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY292654.1.gene1.p1 Protein 3e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AF252622.2.gene2.p01 Protein 4e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AF252623.2.gene1.p01 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY847148.1.gene1.p01 Protein 1e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC HM755448.1.gene1.p01 Protein 3e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AJ416345.gene.p01 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC EU545409.1.gene1.p1 Protein 2e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ211987.1.gene1.p01 Protein 4e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AF325134.1.gene1.p1 Protein 1e-37 47
blaC YP_007268754.1 Class A beta-lactamase BlaC EU177100.1.gene1.p01 Protein 3e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC JF274242.1.gene1.p01 Protein 3e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY847144.1.gene1.p01 Protein 5e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC EU202673.2.gene1.p2 Protein 5e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AY847147.1.gene1.p01 Protein 9e-38 47
blaC YP_007268754.1 Class A beta-lactamase BlaC AF367983.gene.p01 Protein 3e-50 46
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ663489.gene.p01 Protein 2e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ328639.gene.p01 Protein 4e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC Y14156.1.gene1.p01 Protein 2e-35 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AY005110.1.gene1.p1 Protein 4e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC X92506.gene.p01 Protein 1e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ885477.1.gene1.p01 Protein 3e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ223685.1.gene1.p01 Protein 4e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ061159.1.gene1.p01 Protein 1e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AY080894.1.gene1.p01 Protein 3e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AB177384.1.gene1.p01 Protein 3e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC HQ398214.1.gene1.p01 Protein 2e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC EF210159.1.gene1.p01 Protein 4e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC EF219142.1.gene1.p01 Protein 1e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ810789.1.gene1.p01 Protein 3e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AF488377.1.gene1.p1 Protein 4e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC EF426798.1.gene1.p1 Protein 3e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC Y10278.1.gene1.p01 Protein 4e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AJ557142.gene.p01 Protein 3e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ268764.2.gene6.p01 Protein 6e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AJ704396.1.gene1.p01 Protein 6e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AY995206.gene.p01 Protein 8e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AY029068.1.gene1.p1 Protein 3e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AY649755.1.gene1.p01 Protein 7e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC DQ256091.1.gene1.p1 Protein 1e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ873739.1.gene1.p01 Protein 9e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AJ549244.1.gene1.p01 Protein 8e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC HQ166709.1.gene1.p01 Protein 7e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AY267213.1.gene1.p01 Protein 7e-38 46
blaC YP_007268754.1 Class A beta-lactamase BlaC HQ398215.1.gene1.p01 Protein 2e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AF255298.1.gene1.p1 Protein 1e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AY515297.1.gene1.p1 Protein 3e-36 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AY598759.gene.p01 Protein 1e-37 46
blaC YP_007268754.1 Class A beta-lactamase BlaC AB205197.1.gene1.p01 Protein 5e-37 45
blaC YP_007268754.1 Class A beta-lactamase BlaC AY750914.gene.p01 Protein 4e-37 45
blaC YP_007268754.1 Class A beta-lactamase BlaC AY303807.gene.p01 Protein 1e-37 45
blaC YP_007268754.1 Class A beta-lactamase BlaC JN227085.1.gene1.p01 Protein 4e-37 45
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ815436.1.gene1.p01 Protein 2e-36 45
blaC YP_007268754.1 Class A beta-lactamase BlaC AF189721.1.gene1.p01 Protein 7e-37 44
blaC YP_007268754.1 Class A beta-lactamase BlaC FJ214369.1.gene1.p1 Protein 2e-37 44
blaC YP_007268754.1 Class A beta-lactamase BlaC Z28968.gene.p01 Protein 3e-34 43
blaC YP_007268754.1 Class A beta-lactamase BlaC AF275256.gene.p01 Protein 7e-36 43
blaC YP_007268754.1 Class A beta-lactamase BlaC AJ866988.1.gene1.p01 Protein 1e-25 42
blaC YP_007268754.1 Class A beta-lactamase BlaC U50278.1.gene2.p01 Protein 5e-35 41
blaC YP_007268754.1 Class A beta-lactamase BlaC AF535128.1.gene1.p01 Protein 3e-24 41
blaC YP_007268754.1 Class A beta-lactamase BlaC AY070258.1.gene1.p1 Protein 2e-24 41
blaC YP_007268754.1 Class A beta-lactamase BlaC U14748.1.gene2.p01 Protein 1e-29 41