Gene Information

Name : guaB (BN45_50107)
Accession : YP_007268517.1
Strain : Mycobacterium canettii CIPT 140070017
Genome accession: NC_019952
Putative virulence/resistance : Unknown
Product : Putative inosine-5'-monophosphate dehydrogenase GuaB1 (IMP dehydrogenase) (IMPDH) (IMPD)
Function : -
COG functional category : -
COG ID : -
EC number : 1.1.1.205
Position : 2169926 - 2171362 bp
Length : 1437 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11271494, 12657046, 15525680; Product type pe : putative enzyme

DNA sequence :
ATGAGATTTCTGGACGGGCATCCACCCGGGTACGACCTGACATACAACGACGTGTTCATCGTTCCGAACCGATCCGAGGT
CACGTCCCGATTTGACGTCGATTTGTCCACCGCCGACGGCTCGGGCACCACCATTCCGGTGGTGGTCGCCAACATGACCG
CGGTAGCCGGACGGCGGATGGCCGAGACCGTCGCCCGCCGCGGTGGCATCGTGATCTTGCCGCAGGATCTGCCGATCCCG
GCGGTGCAGCAGACGGTGGAGTTCGTCAAAAGCCGAGACCTGGTGCTCGACACCCCAGTGACGCTGGCACCCGACGATTC
AGTGTCCGACGCCATGGCGCTCATCCACAAGCGCGCACATGGCGTCGCGGTGGTCATCCGCGAGGGTCGCCCGATCGGAT
TGGTGCGCGAATCGTCCTGCCTGGGCGTGGATCGCTTCACCCGGGTGCGCGATATCGCCGTGACGGACTACGTGACCGCT
CCGGCGGGAACCGAGCCACGCAAGATCTTCGACCTGCTGGAGCACGCCCCGGTCGACGTCGCGGTGCTGACCGACGCCGA
CGGCACGTTGGCGGGAGTGCTGAGCCGCACCGGGGCTATCCGCGCCGGTATCTACACCCCGGCCACCGACAGCGCGGGCC
GGCTGCGGATCGGCGCGGCCGTCGGCATCAACGGGGACGTGGGCGCCAAGGCCCGAGCGCTCGCCGAAGCCGGCGTCGAC
GTGCTGGTCATCGACACCGCACACGGACACCAGGTCAAGACGTTGGACGCGATCAAGGCGGTCTCGGCACTGGACTTGGG
TTTGCCGCTGGCGGCGGGAAACGTGGTGTCGGCGGAGGGCACCCGGGATCTGCTGAAAGCCGGGGCGAACGTCGTCAAGG
TCGGTGTCGGCCCCGGCGCCATGTGCACCACCCGAATGATGACCGGTGTCGGCCGCCCGCAGTTCTCCGCTGTGCTCGAA
TGCGCTTCTGCGGCAAGACAGCTCGGTGGCCATGTCTGGGCCGACGGCGGGATCCGGCATCCACGCGACGTGGCTCTGGC
GCTGGCCGCCGGCGCCTCGAACGTGATGATCGGGTCGTGGTTCGCCGGCACCTACGAATCCCCCGGGGACCTAATGCGTG
ACCGCGACGATCAGCCGTACAAGGAGAGCTACGGCATGGCATCCAAGCGCGCGGTGGTGGCCCGGGCCGGCGCGGACAAC
CCGTTCGACCGAGCTCGCAAGGCGTTGTTCGAGGAAGGCATCTCGACGTCGCGGATGGGCCTTGACCCCGACCGCGGCGG
TGTGGAGGACTTAATTGACCACATCACTTCTGGCGTGCGCAGCACCTGCACCTATGTGGGTGCCTCGAACCTGGCGGAAC
TGCATGAGCGGGCCGTGGTGGGCGTGCAGTCGGGAGCGGGCTTTGCCGAGGGCCATCCGCTGCCCGCCGGCTGGTGA

Protein sequence :
MRFLDGHPPGYDLTYNDVFIVPNRSEVTSRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPIP
AVQQTVEFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVIREGRPIGLVRESSCLGVDRFTRVRDIAVTDYVTA
PAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGVD
VLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVLE
CASAARQLGGHVWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARAGADN
PFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 3e-132 58
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 3e-132 58
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 3e-132 58
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 1e-132 58