Gene Information

Name : lysX (BN45_40111)
Accession : YP_007268319.1
Strain : Mycobacterium canettii CIPT 140070017
Genome accession: NC_019952
Putative virulence/resistance : Unknown
Product : Lysyl-tRNA synthetase 2 LysX
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 1911858 - 1915193 bp
Length : 3336 bp
Strand : -
Note : Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12657046, 12775759, 15525680, 15928073, 19649276; Product type e : enzyme

DNA sequence :
GTGACACTCACCAAACCTCGCTCGGCCACCAGGGGAAACTCCCGGTATCACTGGGTTCCCGCGGCAGCCGGCTGGACCGT
CGGCGTGATCGCGACCCTGTCACTACTGGCCAGTGTGTCGCCGTTGATTCGGTGGATCATCAAGGTTCCGCGCGAATTCA
TTAACGATTATCTGTTCAACTTCCCCGACACCAACTTCGCGTGGTCCTTCGTGCTGGCATTGCTGGCCGCCGCGTTAACG
GCACGCAAACGCATTGCCTGGTTGGTCTTGCTGGCAAATATGGTCCTGGCCGCCGTGGTCAACGCCGCCGAGATCGCAGC
GGGCGGCAACACCGCCGCCGAGAGCTTCGGGGAGAATCTCGGATTCGCCGCGCATGTTGTGGCAATCGTCGTTCTGGTGC
TGGGCTATCGGGAGTTCTGGGCCAAGGTCCGCAGGGGCGCGCTGTTTCGGGCGGCTGCGGTGTGGCTTGCCGGCGCGGTG
GTCGGAATCGTGGCGTCTTGGGGTCTGGTCGAACTGTTTCCGGGATCACTAGCGCCGGACGAGCGGTTGGGTTACGCGGC
CAACCGGGTGGTCGGATTCGCCCTCGCCGATCCCGATCTGTTCACCGGCAGACCGCACGTCTTCCTCAACGCGATCTTCG
GGTTGTTCGGCGCGTTCGCGTTGATCGGGGCTGCGATCGTCTTGTTCCTATCTCAGCGCGCTGACAATGCGCTGACCGGA
GAGGACGAATCCGCTATCCGCGGGTTATTGGATTTGTATGGGAAGGACGACTCACTGGGCTACTTCGCCACCCGTCGCGA
CAAGTCGGTGGTATTCGCATCCAGCGGCCGCGCCTGTATCACCTACCGTGTCGAGGTCGGTGTCTGCCTAGCCAGCGGCG
ACCCGGTAGGCGACCACAGAGCATGGCCGCAGGCTGTCGACGCGTGGCTGCGGCTGTGCCAGACCTACGGCTGGGCACCC
GGCGTGATGGGCGCCAGTTCACAAGGGGCTCAGACATATCGCGAAGCGGGCCTAACCGCGCTCGAGCTGGGCGATGAGGC
CATCCTGCGGCCAGCCGATTTCAAGTTGTCCGGCCCGGAGATGCGCGGGGTGCGCCAGGCCGTGACGCGGGCCCGGCGGG
CGGGGTTGACGGTGCGCATCCGGCGGCATCGCGACATTGCCGAAGACGAGATGGCGCAGACCATCACACGGGCGGATTCC
TGGCGCGACACCGAGACCGAGCGCGGCTTCTCGATGGCGCTGGGCCGCCTCGGCGACCCCGCGGACTCCGACTGCCTGCT
GGTGGAGGCGATTGATCCGCACAACCAGGTGCTGGCAATGCTGTCGCTGGTGCCGTGGGGAACCACCGGTGTCTCCCTGG
ATTTGATGCGTCGTTCTCCACAATCCCCGAACGGCACTATCGAACTTATGGTCAGCGAACTCGCCTTGCACGCTGAAAGC
CTTGGTATCACTCGTATTTCGTTGAACTTCGCGGTGTTTCGCGCGGCCTTCGAGCAGGGCGCCCAACTCGGCGCCGGCCC
GGTTGCCCGGTTGTGGCGGGGGCTGCTGGTCTTCTTCTCACGGTGGTGGCAGCTCGAGACGCTCTACCGCTCCAACATGA
AGTACCAACCCGAATGGGTACCGCGCTACGCCTGCTACGAAGACGCCCGAGTGATTCCCCGAGTGGGCGTCGCCTCGGTG
ATCGCAGAGGGGTTCCTCGTGCTGCCGTTCAGCCGGCGCAACCGAGTACACACGGGGCATCATCCGGCAGTGCCCGAGCG
GTTGGCGGCCACCGGCCTATTGCATCACGACGGCTCGGCACCGGACGTGAGCGGGCTGCGGCAAGTAGGCCTCACCAATG
GCGACGGGGTCGAGCGGCGGCTACCCGAGCAGGTGCGAGTTCGGTTCGACAAGCTAGAGAAGCTGCGGAGCAGCGGCATT
GACGCCTTTCCCGTGGGCCGGCCGCCCAGTCACACGGTGGCACAGGCGCTGGCCGCAGACCACCCGGCTAGCGTGTCGGT
GTCCGGACGCATCATGCGAATACGTAACTACGGTGGTGTGTTGTTCGCCCAGCTGCGCGACTGGTCGGGCGAAATGCAAG
TGCTGCTGGATAATTCACGCCTGGACCAGGGCTGCGCGGCCGACTTCAACGCGGCGACCGATCTGGGTGATCTGGTGGAG
ATGACCGGACACATGGGCGCCAGCAAGACCGGAACTCCATCGTTGATCGTCAGCGGCTGGCGCCTGATCGGTAAGTGTTT
GCGGCCGTTGCCGAATAAGTGGAAGGGGCTACTGGATCCCGAAGCCCGAGTCCGGACCCGTTACCTCGACCTGGCGGTCA
ACGCTGAGTCCCGTGCGCTGATCACCGCTCGCAGCAGCGTCCTGCGCGCTGTGCGCGAGACGCTGTTCGCAAAGGGATTC
GTCGAGGTCGAAACGCCGATCCTGCAGCAGCTGCACGGCGGCGCCACCGCCCGACCGTTCGTCACGCACATCAACACGTA
TTCCATGGATCTGTTCCTGCGCATCGCACCAGAGCTCTACCTCAAGCGCCTGTGCGTCGGCGGCGTGGAACGGGTATTCG
AGCTCGGCCGTGCCTTTCGCAACGAGGGCGTCGACTTCAGCCACAACCCGGAGTTCACCCTACTGGAGGCCTATCAAGCA
CACGCCGACTACCTTGAGTGGATTGACGGCTGCCGCGAACTCATCCAGAACGCCGCCCAGGCCGCCAACGGGGCGCCCAT
CGCCATGCGGCCCCGGACGGACAAGGGTTCCGACGGCACCCGCCACCACCTCGAACCGGTCGACATCTCCGGGATATGGC
CGGTGCGGACGGTGCATGATGCGATCTCGGAAGCACTCGGTGAACGCATCGACGCCGATACCGGCTTGACCACTCTCCGC
AAGCTGTGCGACGCCGCCGGTGTCCCCTATCGGACCCAATGGGATGCCGGCGCGGTCGTGCTCGAGCTATACGAGCACCT
GGTGGAGTGCCGCACCGAGCAACCGACGTTCTACATCGACTTTCCGACATCGGTGTCACCGTTGACCCGACCGCATCGCA
GCAAGCGCGGTGTCGCCGAGCGTTGGGACCTGGTGGCGTGGGGTATCGAGCTGGGCACCGCCTACAGCGAGCTGACCGAC
CCGGTGGAGCAACGGCGCCGCCTGCAGGAGCAGTCCCTGCTGGCCGCCGGCGGAGACCCCGAGGCGATGGAACTCGACGA
AGACTTCCTGCAAGCGATGGAGTACGCCATGCCGCCCACCGGCGGCTTGGGCATGGGCATTGACCGGGTGGTCATGCTGA
TCACTGGGCGCAGCATTCGCGAAACACTGCCCTTTCCGTTGGCAAAACCGCATTAG

Protein sequence :
MTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALT
ARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAAHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAV
VGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTG
EDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAP
GVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADS
WRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAES
LGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASV
IAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGI
DAFPVGRPPSHTVAQALAADHPASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVE
MTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGF
VEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQA
HADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLR
KLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTD
PVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 9e-155 43
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-155 43
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-155 43
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-155 43