Gene Information

Name : tkt (BN45_30541)
Accession : YP_007268136.1
Strain : Mycobacterium canettii CIPT 140070017
Genome accession: NC_019952
Putative virulence/resistance : Unknown
Product : Transketolase Tkt (TK)
Function : -
COG functional category : -
COG ID : -
EC number : 2.2.1.1
Position : 1689231 - 1691333 bp
Length : 2103 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10537214, 11271494, 12657046, 15525680, 17443846; Product type e : enzyme

DNA sequence :
GTGACCACGCTCGAAGAGATCTCCGCGCTTACCCAACCGCGCCATCCTGACGACTGGACCGAGATCGACTCGGCGGCCGT
CGACACCGCCCGGGTACTGGCCGCCGACGCCGTCCAAAAGGTCGGTAACGGTCATCCTGGAACGGCGATGAGCCTGGCCC
CGTTGGCCTACACGCTGTTTCAGCGGACGATGCGCCACGATCCCAGCGACACACACTGGCTGGGCCGCGATCGGTTCGTG
CTGTCGGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATCGC
GTCGTTGCGCACCTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACCCCCGGCGTCGAGATCACCACCGGCC
CACTGGGGCAGGGACTGGCGTCGGCGGTCGGGATGGCGATGGCCTCGCGCTACGAACGCGGCCTGTTCGACCCGGACGCC
GAACCGGGCGCCAGCCCCTTCGACCACTACATCTACGTCATCGCCTCCGACGGCGACATCGAAGAAGGGGTGACCTCGGA
GGCGTCGTCGCTGGCCGCGGTCCAGCAACTGGGCAACCTCATCGTGTTCTACGACCACAACCAGATCTCGATCGAGGACG
ACACCAACATCGCGTTGTGCGAGGACACCACCGCCCGCTACCGCGCCTACGGCTGGCACGTGCACGAGGTGGAGGGCGGC
GAGAACGTCGTCGCCATCGAGGAGGCCATCGCCAACGCGAAAGCCGTCCCCGACCGGCCCTCGTTCATCGCGCTGCGCAC
CGTCATCGGCTATCCGGCGCCGAACCTGATGAACACCGGCAAGGCGCATGGCGCGGCCCTCGGCGACGACGAGGTGGCCG
CAGTCAAGAAGATCCTCGGCTTCGATCCCGACAAGGCGTTCGAGGTCCGGGAGGACGTCCTCACCCACACCCGAGGGCTG
GTGGCCCGCGGCAAACAGGCCCACGAACGCTGGCAGCTCGAATTCGATGCCTGGGCGCGGCGCGAACCCGAACGCAAGGC
GCTATTGGACCGGCTGCTCGCGCATCGGCTGCCCGACGGCTGGGACGCCGACCTGCCGCACTGGGAACCCGGGTCCAAAG
CGCTGGCCACTCGTGCCGCCTCCGGCTCGGTGCTGGCCGCGATAGGACCGAAACTGCCCGAGTTGTGGGGTGGTTCGGCC
GACCTGGCGGGCAGCAACAACACCACCATCAAAGGCGCCGACTCCTTTGGCCCGCCCTCGATTTCGACCAAGGAGTACAC
CGCGCACTGGTACGGCCGCACCCTGCACTTCGGTGTTCGCGAACACGCGATGGGCGCCATCCTGTCCGGCATCGTGCTGC
ACGGCCCCACCCGAGCCTACGGCGGCACCTTCCTGCAGTTCTCCGACTACATGCGCCCCGCGGTGCGGCTGGCGTCGCTG
ATGGACATCGACACCATCTATGTGTGGACGCACGACTCGATCGGGCTCGGCGAAGACGGGCCCACCCACCAGCCGATCGA
GCACCTCTCGGCGCTGCGCGCGATTCCGCGGCTCTCGGTGGTGCGCCCGGCCGACGCCAACGAGACGGCCTACGCCTGGC
GCACGATCCTGGCCCGCGGCAACGGCAGTGGGCCGGTCGGGTTGATCCTGACCCGCCAAGGTGTGCCGGTGCTGGACGGC
ACCGACGCCGAAGGGGTTGCCCGCGGCGGGTACGTGCTGAGTGACGCCGGTGGTCTGCAACCGGGCGAGGAACCCGACGT
CATTCTCATCGCCACCGGCTCGGAGGTACAGCTGGCGGTCGCGGCGCAGACGTTGTTGGCCGACAACGACATCCTCGCCC
GGGTGGTGTCGATGCCGTGTCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTG
TCGGCCCGGGTCGCCGTCGAGGCCGGCGTCGCGCAATGCTGGCACAAGCTGGTCGGCGACACCGGCGAGATCGTCTCGAT
CGAGCACTACGGCGAATCCGCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACCGCCGAGGCCGTGGCCGCCGCCG
CCGAACGAGCGCTGGATAACTGA

Protein sequence :
MTTLEEISALTQPRHPDDWTEIDSAAVDTARVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFV
LSAGHSSLTLYIQLYLGGFGLELSDIASLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA
EPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDHNQISIEDDTNIALCEDTTARYRAYGWHVHEVEGG
ENVVAIEEAIANAKAVPDRPSFIALRTVIGYPAPNLMNTGKAHGAALGDDEVAAVKKILGFDPDKAFEVREDVLTHTRGL
VARGKQAHERWQLEFDAWARREPERKALLDRLLAHRLPDGWDADLPHWEPGSKALATRAASGSVLAAIGPKLPELWGGSA
DLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLASL
MDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARGNGSGPVGLILTRQGVPVLDG
TDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTV
SARVAVEAGVAQCWHKLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 7e-113 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-112 42