Gene Information

Name : BN42_20182 (BN42_20182)
Accession : YP_007263170.1
Strain : Mycobacterium canettii CIPT 140070010
Genome accession: NC_019951
Putative virulence/resistance : Virulence
Product : Putative aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 562507 - 564030 bp
Length : 1524 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12657046, 12775759; Product type pe : putative enzyme

DNA sequence :
ATGACTGTCTTTTCCCGTCCCGGTTCCGCCGGGGCGCTGATGTCCTATGAATCCCGGTACCAAAACTTCATCGGGGGCCA
GTGGGTCGCGCCGGTCCATGGGCGCTACTTCGAGAACCCGACGCCGGTGACCGGCCAGCCGTTCTGCGAGGTACCGCGCT
CCGACGCGGCCGACATCGACAAGGCGCTCGACGCGGCGCACGCGGCGGCGCCGGGGTGGGGCAAGACCGCACCGGCCGAA
CGGGCGGCGATCCTCAACATGATCGCCGACCGCATCGACAAGAACGCCGCCGCGCTGGCGGTGGCCGAGGTCTGGGACAA
CGGGAAACCGGTCCGGGAAGCGCTGGCCGCCGATCTCCCGTTGGCGGTCGATCACTTCCGGTACTTCGCCGCGGCGATCC
GCGCCCAGGAGGGCGCCCTGAGCCAGATCGACGAGGACACCGTGGCCTACCACTTCCACGAGCCGCTCGGCGTGGTGGGC
CAGATCATTCCGTGGAACTTCCCCATCCTGATGGCGGCCTGGAAGCTGGCGCCGGCGTTGGCGGCGGGCAACACGGCGGT
GCTCAAACCCGCCGAGCAGACACCCGCCTCGGTGCTCTACCTGATGTCGCTAATCGGTGATCTGTTGCCGCCCGGGGTGG
TCAACGTGGTCAACGGATTCGGCGCCGAGGCCGGCAAGCCGTTGGCCTCCAGCGACCGCATCGCCAAGGTCGCGTTCACC
GGGGAAACCACCACGGGGCGGCTGATCATGCAATACGCCTCGCACAACCTGATCCCGGTCACCCTGGAACTCGGCGGCAA
GAGCCCCAACATCTTCTTCGCCGACGTGCTGGCCGCCCACGACGACTTCTGCGACAAAGCGCTGGAAGGCTTCACCATGT
TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGCAGTCTGATCCAGGCCGACATCTACGACGAGTTCCTGGAG
CTGGCGGCGATCCGGACCAAGGCGGTCCGCCAAGGCGATCCGCTGGACACCGAAACCATGCTGGGTTCCCAGGCCTCCAA
CGACCAGCTGGAAAAGGTGTTGTCCTACATCGAAATCGGCAAGCAAGAGGGTGCGGTGATTATCGCCGGAGGCGAGCGCG
CCGAACTAGGCGGCGACCTGTCCGGCGGTTATTACATGCAGCCGACGATCTTCACCGGCACCAACAACATGCGGATTTTC
CAGGAGGAGATCTTCGGGCCGGTGGTCGCCGTGACGTCCTTCACCGATTACGACGACGCGATCGGCATCGCCAACGACAC
CCTCTACGGCTTGGGTGCCGGTGTGTGGAGCCGCGACGGCAACACCGCTTATCGGGCCGGGCGGGACATCGCGGCCGGCC
GGGTGTGGGTTAACTGCTACCACCTCTACCCCGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGGGAG
GGCCACCAGATGATGCTGCAGCACTACCAGCACACCAAGAACCTGCTGGTGTCCTACTCGGATAAGGCGCTGGGGTTCTT
CTGA

Protein sequence :
MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAE
RAAILNMIADRIDKNAAALAVAEVWDNGKPVREALAADLPLAVDHFRYFAAAIRAQEGALSQIDEDTVAYHFHEPLGVVG
QIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT
GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLE
LAAIRTKAVRQGDPLDTETMLGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNMRIF
QEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAGRDIAAGRVWVNCYHLYPAHAAFGGYKQSGIGRE
GHQMMLQHYQHTKNLLVSYSDKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-128 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-135 60
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-135 60
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-135 60
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-135 60
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BN42_20182 YP_007263170.1 Putative aldehyde dehydrogenase VFG0082 Protein 6e-129 61