Gene Information

Name : guaA (BN42_50054)
Accession : YP_007266120.1
Strain : Mycobacterium canettii CIPT 140070010
Genome accession: NC_019951
Putative virulence/resistance : Unknown
Product : GMP synthetase (glutamine aminotransferase)
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 3927332 - 3928909 bp
Length : 1578 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2982857, 3894345, 85261223, 8548458; Product type e : enzyme

DNA sequence :
GTGGTGCAGCCTGCTGACATCGACGTGCCTGAGACACCGGCTCGACCGGTGTTGGTGGTCGACTTCGGTGCCCAATATGC
CCAGTTGATTGCCCGTCGGGTTCGAGAAGCACGGGTTTTCTCCGAGGTGATTCCGCACACCGCCTCGATCGAGGAGATCA
GGGCCCGTCAGCCGGTGGCGCTCGTGCTTTCCGGTGGACCGGCCAGTGTCTACGCCGACGGCGCTCCGAAACTCGATCCG
GCGCTACTGGACCTCGGTGTACCGGTTCTTGGCATCTGCTACGGGTTTCAGGCCATGGCGCAGGCGCTCGGGGGGACCGT
CGCCCACACCGGCACTCGCGAATACGGTCGGACTGAACTGAAAGTCCTTGGTGGCAAACTGCATTCGGATCTTCCCGAGG
TTCAGCCGGTATGGATGAGTCACGGTGACGCGGTCACGGCCGCGCCGGACGGATTCGACGTGGTGGCTAGCAGCGCCGGT
GCCCCGGTGGCCGCCTTCGAGGCCTGCGACCGGCGCCTGGCCGGGGTGCAGTATCACCCGGAGGTGATGCACACCCCACA
CGGGCAACAGGTGCTCAGCCGGTTTTTGCACGACTTCGCCGGGCTCGGCGCCCAGTGGACGCCCGCCAACATCGCCAACG
CGCTGATCGAGCAGGTGCGCACCCAGATCGGCGACGGCCACGCCATCTGCGGGCTATCCGGCGGCGTGGATTCCGCGGTG
GCCGCGGCCCTGGTGCAGCGGGCCATCGGCGACCGGTTGACCTGTGTCTTCGTCGACCACGGGCTGTTGCGCGCCGGTGA
GCGGGCGCAGGTGCAACGCGATTTCGTGGCCGCTACCGGCGCCAACCTGGTCACCGTCGACGCGGCCAAGACCTTCCTCG
AGGCGCTGTCGGGCGTGAGCGCCCCCGAGGGCAAGCGCAAGATCATCGGCCGTCAGTTCATCCGCGCGTTCGAGGGCGCG
GTGCGGGATGTGCTGGACGGTAAGACTGCTGAGTTCCTGGTTCAGGGCACGCTGTATCCGGATGTGGTGGAGTCCGGCGG
GGGCAGCGGCACCGCGAACATCAAGAGCCACCACAATGTCGGCGGCCTGCCCGACGACCTGAAGTTCACCCTCGTTGAGC
CGCTGCGGCTGCTGTTCAAAGACGAGGTGCGCGCGGTCGGGCGGGAGTTGGGTCTGCCGGAGGAGATCGTGGCGCGCCAG
CCGTTTCCGGGACCGGGGTTGGGGATTCGGATCGTCGGGGAGGTCACCGCCAAGCGTTTGGATACGCTGCGGCGCGCCGA
TTCGATCGTGCGTGAGGAGCTGACCGCGGCGGGCCTGGACAACCAGATCTGGCAGTGTCCGGTGGTGCTGTTGGCCGATG
TCCGCTCGGTGGGTGTGCAGGGTGACGGTCGCACCTATGGCCACCCGATCGTGCTGCGTCCGGTGTCGAGTGAAGACGCG
ATGACCGCCGACTGGACCCGGGTGCCCTACGAGGTGCTCGAGCGCATCTCGACCCGGATCACCAACGAGGTCGCCGAGGT
CAACCGCGTGGTGCTGGACATCACCAGCAAGCCGCCCGCCACCATCGAGTGGGAGTAG

Protein sequence :
MVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTASIEEIRARQPVALVLSGGPASVYADGAPKLDP
ALLDLGVPVLGICYGFQAMAQALGGTVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAAPDGFDVVASSAG
APVAAFEACDRRLAGVQYHPEVMHTPHGQQVLSRFLHDFAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAV
AAALVQRAIGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAKTFLEALSGVSAPEGKRKIIGRQFIRAFEGA
VRDVLDGKTAEFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGLPEEIVARQ
PFPGPGLGIRIVGEVTAKRLDTLRRADSIVREELTAAGLDNQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDA
MTADWTRVPYEVLERISTRITNEVAEVNRVVLDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 78
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-130 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-130 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-130 51