Gene Information

Name : tpx (BN42_30225)
Accession : YP_007264676.1
Strain : Mycobacterium canettii CIPT 140070010
Genome accession: NC_019951
Putative virulence/resistance : Virulence
Product : Putative thiol peroxidase Tpx
Function : -
COG functional category : -
COG ID : -
EC number : 1.11.1.-
Position : 2294884 - 2295381 bp
Length : 498 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10493122, 10510226, 10768780, 11271494, 12657046, 17443846, 9673225; Product type pe : putative enzyme

DNA sequence : 
ATGGCACAGATAACCCTGCGAGGAAACGCGATCAATACCGTCGGTGAGCTACCTGCTGTCGGATCCCCGGCCCCGGCCTT
CACCCTGACAGGGGGCGATCTGGGGGTGATCAGCAGCGACCAGTTCCGGGGTAAGTCCGTGTTGCTGAACATCTTTCCAT
CCGTGGACACACCGGTGTGCGCGACGAGTGTGCGAACCTTCGACGAGCGTGCGGCGGCAAGTGGCGCTACCGTGCTGTGT
GTCTCGAAGGATCTGCCGTTCGCCCAGAAGCGCTTCTGCGGCGCCGAGGGCACCGAAAACGTCATGCCCGCGTCGGCATT
CCGGGACAGCTTCGGCGAGGATTACGGCGTGACCATCGCCGACGGGCCGATGGCCGGGCTGCTCGCCCGCGCAATCGTGG
TGATCGGCGCGGACGGCAACGTCGCCTACACGGAATTGGTGCCGGAAATCGCGCAAGAACCCAACTACGAAGCGGCGCTG
GCCGCGCTGGGCGCCTAG

Protein sequence : 
MAQITLRGNAINTVGELPAVGSPAPAFTLTGGDLGVISSDQFRGKSVLLNIFPSVDTPVCATSVRTFDERAAASGATVLC
VSKDLPFAQKRFCGAEGTENVMPASAFRDSFGEDYGVTIADGPMAGLLARAIVVIGADGNVAYTELVPEIAQEPNYEAAL
AALGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-33 44
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-33 44
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-33 43
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-33 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_007264676.1 Putative thiol peroxidase Tpx VFG0087 Protein 4e-34 44