Gene Information

Name : ureC (BN42_30113)
Accession : YP_007264576.1
Strain : Mycobacterium canettii CIPT 140070010
Genome accession: NC_019951
Putative virulence/resistance : Virulence
Product : Urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 2181107 - 2182840 bp
Length : 1734 bp
Strand : +
Note : Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme

DNA sequence :
ATGGCGCGGCTGTCAAGGGAGCGCTACGCGCAGGTGTACGGACCTACCACCGGCGACCGGATCCGGCTGGCCGACACCAA
CCTGCTGGTTGAGGTCACCGAAGACCGGTGCGGGGGACCGGGACTGGCCGGTGACGAGGCGGTGTTCGGCGGCGGCAAGG
TGCTGCGCGAGTCCATGGGCCAGGGCCGTGCGAGCCGGGCCGACGGTGCCCCCGACACCGTGATCACCGGTGCGGTGATC
ATCGACTACTGGGGAATCATCAAGGCCGACATCGGGATTCGCGATGGCCGCATCGTCGGGATCGGAAAGGCCGGCAATCC
CGACATCATGACAGGTGTGCATCGCGATCTCGTCGTCGGGCCGTCCACCGAAATCATCAGCGGCAACCGTCGAATCGTCA
CCGCGGGCACCGTCGACTGTCACGTGCACTTGATCTGTCCGCAGATCATCGTCGAAGCCCTGGCCGCGGGCACCACCACG
ATCATCGGCGGAGGCACCGGACCCGCCGAGGGCACCAAGGCCACCACAGTCACCCCCGGCGAGTGGCACCTGGCCCGGAT
GCTGGAGTCACTGGACCGTTGGCCGGTAAACTTCGCGCTGCTCGGCAAGGGAAACACCGTGAATCCCGACGCACTGTGGG
AACAGTTGCGCGGTGGCGCATCGGGTTTCAAACTGCACGAAGACTGGGGATCGACCCCGGCGGCCATCGACACCTGCCTG
ACCGTCGCCGACGTGGCCGGGGTGCAAGTTGCGCTGCACTCCGACACCCTCAACGAGACCGGATTCGTCGAGGACACCAT
CGGCGCGATCGCCGGACGTTCGATTCACGCCTACCACACCGAGGGCGCCGGCGGCGGGCACGCACCGGACATCATTACCG
TCGCGGCGCAACCGAATGTGCTGCCCAGCTCGACCAATCCGACCCGCCCGCATACGGTGAACACCCTCGACGAGCACCTC
GACATGCTGATGGTGTGCCACCACCTCAACCCCCGGCTCCCGGAGGACCTCGCGTTTGCCGAAAGCCGGATCCGACCGTC
CACCATCGCGGCAGAAGATCTGTTGCACGATATGGGGGCAATCTCGATGATTGGCAGCGATTCCCAGGCGATGGGCCGCG
TCGGCGAGGTGGTGCTGCGCACCTGGCAGACCGCGCACGTGATGAAAGCCCGCCGCGGGGCACTCGACGGTGACCCGTCC
GGTAGCCAAGCCGCCGACAACAACCGGGTCCGCCGCTACATCGCCAAATACACCATCTGCCCGGCAATCGCACACGGCAT
GGACCGCCTGATCGGTTCGGTGGAGGTGGGAAAGTTGGCCGACCTGGTGTTGTGGGAGCCGGCGTTCTTTGGGGTGCGTC
CGCACGTCGTGCTCAAAGGCGGGGCGATCGCCTGGGCGGCGATGGGCGACGCGAACGCGTCGATCCCGACCCCGCAACCG
GTGCTCCCGCGACCGATGTTCGGCGCGGCTGCGGCAACCGCGGCGGCGACCTCGGTGCACTTCGTCGCGCCGCAATCCAT
CGACGCGCGCCTGGCGGACCGGCTCGCGGTCAATCGGCGACTAGCGCCGGTGGCCGACGTACGCGCAGTGGGCAAGACCG
ACCTGCCGCTTAATGACGCCCTACCGAGCATCGAGGTCGATCCCGACACCTTCACCGTGCGCATCGACGGCCAGGTGTGG
CAACCGCAGCCGGCCGCCGAACTACCTATGGCACAACGGTATTTCCTGTTCTAA

Protein sequence :
MARLSRERYAQVYGPTTGDRIRLADTNLLVEVTEDRCGGPGLAGDEAVFGGGKVLRESMGQGRASRADGAPDTVITGAVI
IDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVHLICPQIIVEALAAGTTT
IIGGGTGPAEGTKATTVTPGEWHLARMLESLDRWPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCL
TVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPDIITVAAQPNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLNPRLPEDLAFAESRIRPSTIAAEDLLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKARRGALDGDPS
GSQAADNNRVRRYIAKYTICPAIAHGMDRLIGSVEVGKLADLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTPQP
VLPRPMFGAAAATAAATSVHFVAPQSIDARLADRLAVNRRLAPVADVRAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVW
QPQPAAELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-145 62
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-145 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-146 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-146 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-146 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-146 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_007264576.1 Urease subunit alpha VFG0270 Protein 4e-130 55