Gene Information

Name : tkt (BN42_21365)
Accession : YP_007264186.1
Strain : Mycobacterium canettii CIPT 140070010
Genome accession: NC_019951
Putative virulence/resistance : Unknown
Product : Transketolase Tkt (TK)
Function : -
COG functional category : -
COG ID : -
EC number : 2.2.1.1
Position : 1702140 - 1704242 bp
Length : 2103 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10537214, 11271494, 12657046, 15525680, 17443846; Product type e : enzyme

DNA sequence :
GTGACCACGCTCGAAGAGATCTCCGCGCTTACCCAACCGCGCCATCCTGACGACTGGACCGAGATCGATTCGGCTGCCGT
CGACACCATCCGGGTCCTGGCCGCCGATGCCGTCCAAAAGGTCGGCAACGGTCATCCTGGAACGGCGATGAGCCTGGCCC
CGCTGGCTTACACGCTGTTTCAGCGGACGATGCGCCACGATCCCAGCGACACACACTGGCTGGGCCGCGATCGGTTCGTG
CTGTCGGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATCGC
GTCGTTGCGCACCTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACCCCCGGCGTTGAGATCACCACCGGCC
CGCTGGGGCAGGGACTGGCGTCGGCGGTTGGGATGGCGATGGCCTCGCGCTACGAGCGCGGTCTGTTCGACCCGGACGCC
GAACCGGGCGCCAGCCCCTTCGACCACTACATCTACGTCGTCGCCTCCGACGGCGACATTGAAGAAGGGGTGACCTCGGA
GGCGTCGTCGCTGGCCGCGGTCCAGCAACTGGGCAACCTCATCGTGTTCTACGACCGCAACCAGATCTCGATCGAGGACG
ACACCAACATCGCTCTGTGTGAGGACACCGCGGCCCGCTACCGCGCGTACGGCTGGCACGTGCAAGAGGTTGAGGGTGGT
GAGAACGTCGTCGGCATCGAGGAGGCCATCGCCAACGCGAAGGCGGTCACCGACCGGCCCTCGTTCATTGCGCTGCGCAC
CGTCATCGGTTATCCGGCGCCGAACCTGATGGACACCGGCAAGGCGCACGGTGCCGCGCTGGGCGACGACGAGGTGGCCG
CCGTCAAGAAGATCCTCGGCTTCGATCCGGACAAGACGTTCCAGGTCCGCGAGGATGTCCTCACCCACACCCGGGGATTG
GTGGCCCGCGGCAAACAGGTCCACGAACGCTGGCAGCTCGAATTCGATGCCTGGGCAGGGCGCGAACCCGAACGCAAGGC
GCTGCTGGACCGGCTGCTCGCGCAGAAGTTGCCCGACGGCTGGGACGCCGACTTGCCGCGCTGGGAACCGGGGTCCAATG
CGCTGGCCACCCGCGCGGCTTCCGGTGCGGTGCTGTCCGCGCTCGGACCGAAACTTCCCGAGCTGTGGGGGGGTTCGGCC
GACCTGGCCGGCAGCAACAACACCACCATCGCGGGCGTCGACTCCTTTGGCCCGCCCTCGATTTCCACCAAGGAATACAC
CGCGCACTGGTATGGTCGCACCCTGCACTTCGGTGTTCGCGAGCACGCGATGGGCGCCATCCTGTCCGGCATCGTGCTGC
ACGGCCCCACCCGAGCCTACGGCGGCACCTTCCTGCAGTTCTCGGACTACATGCGCCCCGCGGTGCGGCTGGCGTCGCTG
ATGGACATCGACACCATCTATGTGTGGACGCACGACTCGATCGGGCTCGGCGAAGACGGTCCGACCCATCAACCGATCGA
GCACCTCTCGGCGCTGCGCGCGATCCCCCGGCTGTCGGTGGTGCGCCCGGCAGATGCCAACGAGACGGCCTACGCCTGGC
GCACGATCCTGGCCCGCGGCAACGGCAACGGGCCGGTCGGGTTGATCCTGACCCGCCAAGGTGTGCCGGTATTGGCCGGC
ACCGACGCCGAAGGGGTTGCTCGCGGCGGTTACGTGCTGAGTGACGCCGGTGGCCTGCAACCAGGCGAGGAACCCGACGT
CATTCTCATCGCCACCGGCTCGGAGGTACAGCTGGCCGTCGCGGCGCAGACGTTGTTGGCCGACAACGACATCCTCGCCC
GGGTGGTGTCGATGCCGTGCCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTG
TCGGCGCGGGTGGCCGTCGAAGCCGGCGTCGCACAATGCTGGCACCAGCTGGTCGGCGACACCGGCGAGATCGTCTCGAT
CGAGCACTACGGCGAATCTGCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACCGCCGAGGCCGTGGCCGCCGCCG
CCGAACGAGCGCTGGATAACTGA

Protein sequence :
MTTLEEISALTQPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFV
LSAGHSSLTLYIQLYLGGFGLELSDIASLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA
EPGASPFDHYIYVVASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGG
ENVVGIEEAIANAKAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKILGFDPDKTFQVREDVLTHTRGL
VARGKQVHERWQLEFDAWAGREPERKALLDRLLAQKLPDGWDADLPRWEPGSNALATRAASGAVLSALGPKLPELWGGSA
DLAGSNNTTIAGVDSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLASL
MDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARGNGNGPVGLILTRQGVPVLAG
TDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTV
SARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-111 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 4e-113 42