Gene Information

Name : tkt (BN44_11628)
Accession : YP_007260177.1
Strain : Mycobacterium canettii CIPT 140060008
Genome accession: NC_019950
Putative virulence/resistance : Unknown
Product : Transketolase Tkt (TK)
Function : -
COG functional category : -
COG ID : -
EC number : 2.2.1.1
Position : 1628949 - 1631051 bp
Length : 2103 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10537214, 11271494, 12657046, 15525680, 17443846; Product type e : enzyme

DNA sequence :
GTGACCACACTCGAAGAGATCTCCGCGCTTACCCAACCGCGCCATCCCGACGACTGGACCGAGATCGATTCGGCTGCCGT
CGACACCATCCGGGTCCTGGCCGCCGATGCCGTCCAAAAGGTCGGCAACGGTCATCCTGGAACGGCGATGAGCCTAGCTC
CGTTGGCTTACACGCTGTTTCAGCGGACAATGCGCCACGATCCCAGCGACACACACTGGCTGGGCCGCGACCGGTTCGTG
CTCTCGGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATTGA
GTCGTTGCGCACCTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACCCCCGGCGTTGAGATCACCACCGGCC
CGCTGGGGCAGGGCCTGGCGTCGGCGGTCGGGATGGCGATGGCCTCGCGCTACGAGCGCGGCCTGTTCGACCCGGACGCC
GAACCGGGCGCCAGCCCCTTCGACCACTACATCTACGTCGTCGCCTCCGACGGTGACATTGAAGAAGGGGTGACCTCGGA
GGCGTCGTCGCTGGCCGCGGTCCAGCAACTGGGCAACCTCATCGTGTTCTATGACCGCAACCAGATCTCGATCGAGGACG
ACACCAACATCGCGCTGTGTGAGGACACCGCGGCCCGCTACCGCGCCTATGGCTGGCACGTGCAGGAGGTTGAGGGCGGT
GAGAACGTCGTCGGCATCGAGGAGGCCATCGCCAACGCGCAGGCGGTCACCGACCGGCCCTCGTTCATCGCGCTGCGCAC
CGTCATCGGCTATCCGGCGCCGAACCTGATGGACACCGGCAAGGCGCACGGCGCGGCCCTGGGCGACGACGAGGTGGCCG
CAGTCAAGAAGATCCTCGGCTTCGATCCGGACAAGACGTTCCAGGTCCGCGAGGACGTCCTCACCCACACCCGAGGGCTG
GTGGCCCGCGGCAAACAGGCCCACGACCAATGGCAGCTCGAATTCGATGCCTGGGCGCGGCGTGAACCCGAGCGCAAGGC
GCTGCTGGACCGGCTGCTCGCGCAGAAGTTGCCCGACGGCTGGGACGCCGACTTGCCCCACTGGGAACCGGGGTCCAAGG
CGCTGGCCACCCGCGCGGCCTCGGGTGCGGTGCTGTCCGCGCTCGGGCCGAAACTGCCCGAGTTGTGGGGCGGTTCGGCC
GACCTGGCGGGCAGCAACAACACAACGATAAAGGGCGCCGATTCCTTTGGCCCGCCCTCGATTTCCACCAAGGAATACAC
CGCGCACTGGTATGGTCGCACCCTGCACTTCGGTGTTCGCGAGCACGCGATGGGCGCCATCCTGTCCGGCATCGTGCTGC
ACGGCCCCACCCGAGCCTACGGCGGCACCTTCCTGCAGTTCTCCGACTACATGCGCCCCGCGGTGCGGCTGGCGTCGCTG
ATGGACATCGACACCATCTACGTGTGGACGCACGACTCGATCGGGCTCGGCGAAGACGGGCCCACCCACCAGCCGATCGA
GCACCTCTCGGCGCTGCGCGCGATCCCCCGGCTGTCGGTGGTGCGCCCGGCGGACGCCAACGAGACGGCCTACGCCTGGC
GCACAATCCTGGCCCGCGGCAACGGCAACGGGCCCGTCGGGTTGATCCTGACCCGCCAAGGTGTGCCGGTGCTGGACGGC
ACCGACGCCGAGGGGGTTGCCCGCGGCGGGTACGTGCTGAGTGACGCCCCTGGCCTGCAACCGGGCGAGGAACCCGACGT
CATTCTCATCGCCACCGGCTCGGAGGTGCAGCTGGCGGTCGCGGCGCAGACGTTGTTGGCCGACAACGACATCCTCGCTC
GGGTGGTGTCGATGCCGTGCCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTG
TCGGCGCGGGTGGCCGTCGAAGCCGGCGTCGCGCAATGCTGGCACCAGCTGGTTGGCGACACGGGCGAGATCGTCTCGAT
CGAGCACTACGGCGAATCCGCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACTGCCGAGGCCGTGGCCGCCGCCG
CCGAACGAGCGCTGGATAACTGA

Protein sequence :
MTTLEEISALTQPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFV
LSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA
EPGASPFDHYIYVVASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGG
ENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKILGFDPDKTFQVREDVLTHTRGL
VARGKQAHDQWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSA
DLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLASL
MDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARGNGNGPVGLILTRQGVPVLDG
TDAEGVARGGYVLSDAPGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTV
SARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 4e-113 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-112 42