Gene Information

Name : Thimo_0273 (Thimo_0273)
Accession : YP_007242773.1
Strain : Thioflavicoccus mobilis 8321
Genome accession: NC_019940
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 293476 - 294849 bp
Length : 1374 bp
Strand : +
Note : PFAM: ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; flagellar protein export ATPase FliI

DNA sequence :
ATGAGCGTCGCGACGCCGGACTCGTTGGTTCGGAGCGAGCATTGGGCCAATGCGATGCGCGCTTACCGAACCGCGGTGGA
AAATCTCCCGGCGCCGATTGCGCAGGGACGCTTGACGCGAGCGGTCGGCTTGACGCTTGAGGCTGTGGGTTGCCAGGCCG
CCGTCGGTGGCCGCTGTACAATCGAGGCGATGGACGGCTCCGAGGTCGACGCGGAAGTTGTCGGATTCGCCGGGGAGCGG
CTCTATCTGATGTTGGCCGGAGAGGACCGGGGACTCACCGTCAATGCTCGTGTGACACCGGCTCGCCACGGCGGGGGCGT
ACCAGTCGGGCCGGAAATGCTCGGCCGGGTGTTGGACGGCGCTGGCCGCCCTTGGGATGGTCGCGGCCCGTTGCGCGCCC
AAAGCCGAGCACCGCTTCATGGCCGCACCATCAATCCGATGGCCCGAGCGCCGATCGATGAACCGCTGGACGTCGGGGTT
CGGGCGATCAATGCACTTCTGACCGTCGGCCGCGGCCAGCGGATGGGGCTCTTTGCCGGAAGCGGCGTCGGCAAGAGCGC
GTTGCTCGGCATGATGACACGCAATACCAACGCTGACGTGACGGTCGTTGGACTGATCGGTGAGCGCGGCCGTGAGGTTC
GGGAGTTCGTCCAGAATACCCTTGGCGATGAGGGTCGTCGTCGGGCCGTCGTCGTCGCCGTGCCAGCCGATCGGCCCCCG
CTGATGCGCTTGCATGGGGCGATGCTCGCAACCAGCATCGCCGAGTATTTCCGAGATCAGGGCCAGCGGGTCCTGCTGCT
GATGGATTCGCTTACTCGCTATGCGCAGGCCCAGCGTGAGATCGCGCTGGCTATCGGCGAGCCGCCCGCGACCAAAGGCT
ATCCGCCCTCGGTATTCGCCAAGCTGCCGCATCTCGCGGAGCGGGCTGGCGCCGGCGACGGCAAGGGATCGATCACGGCC
TTCTACACCGTGCTTGTCGAGGGGGATGATCAGCTCGATCCCATTGCCGACTCGGCACGCGCGATCCTCGACGGGCACGT
CGTCTTGTCTCGCGCACTCGCTGATGCGGGCCATTACCCAGCCATCGACATCGAGGCTTCGGTAAGTCGACTGATGCACG
AGATCGCCGCAGCGCCACATCAGGAAGCTGCCCGGGGTCTCAAACGCTTGGTCTCTCTCTACAACCGAAACCAAGACCTA
ATCACACTCGGGGCTTATAGAAGAGGGCAGAATGCTGAGCTGGACGAAGCCGTCGAGCGTCGTCCGGCGATTTCGGCGTT
TCTGCGCCAGGGTATGCGCGAGCGGGTCGACCTGCAATCGAGCATCGCGCAGCTAATCGAGCTGATGCAACCGGTGTCTC
GGACCGCTGCATGA

Protein sequence :
MSVATPDSLVRSEHWANAMRAYRTAVENLPAPIAQGRLTRAVGLTLEAVGCQAAVGGRCTIEAMDGSEVDAEVVGFAGER
LYLMLAGEDRGLTVNARVTPARHGGGVPVGPEMLGRVLDGAGRPWDGRGPLRAQSRAPLHGRTINPMARAPIDEPLDVGV
RAINALLTVGRGQRMGLFAGSGVGKSALLGMMTRNTNADVTVVGLIGERGREVREFVQNTLGDEGRRRAVVVAVPADRPP
LMRLHGAMLATSIAEYFRDQGQRVLLLMDSLTRYAQAQREIALAIGEPPATKGYPPSVFAKLPHLAERAGAGDGKGSITA
FYTVLVEGDDQLDPIADSARAILDGHVVLSRALADAGHYPAIDIEASVSRLMHEIAAAPHQEAARGLKRLVSLYNRNQDL
ITLGAYRRGQNAELDEAVERRPAISAFLRQGMRERVDLQSSIAQLIELMQPVSRTAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-87 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-87 51
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-84 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-88 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-88 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-88 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-88 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-87 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-81 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-85 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-85 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-77 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-77 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-78 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-78 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-78 48
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-69 48
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-69 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-68 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 6e-76 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-66 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-66 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-73 46
escN AAC38383.1 EscN Virulence LEE Protein 1e-73 46
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-73 46
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-73 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 9e-74 46
escN CAI43874.1 EscN protein Virulence LEE Protein 6e-74 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 8e-74 46
escN AAK26715.1 EscN Virulence LEE Protein 3e-73 46
escN AAL57542.1 EscN Virulence LEE Protein 3e-73 46
escN AAC31513.1 L0034 Virulence LEE Protein 2e-73 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-73 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-73 46
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-74 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-67 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-68 45
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-64 45
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-64 45
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-64 45
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-64 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-71 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-71 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 7e-72 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-69 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-69 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-68 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-63 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-68 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-66 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG1254 Protein 3e-117 62
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG2331 Protein 1e-106 61
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG2499 Protein 3e-112 61
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG0192 Protein 3e-86 51
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG0390 Protein 1e-85 51
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG0515 Protein 2e-78 48
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG0048 Protein 5e-91 47
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG0812 Protein 1e-73 46
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG0730 Protein 8e-74 46
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG2144 Protein 2e-82 45
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG2459 Protein 7e-69 45
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG0555 Protein 5e-65 45
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG1778 Protein 1e-66 42
Thimo_0273 YP_007242773.1 flagellar protein export ATPase FliI VFG1008 Protein 2e-64 41