Gene Information

Name : BPP43_04650 (BPP43_04650)
Accession : YP_007234457.1
Strain : Brachyspira pilosicoli P43/6/78
Genome accession: NC_019908
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 971354 - 973933 bp
Length : 2580 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGATTATAATAAATATACAATAAAAGCCCAAGAGGCAGTAAATGAAGCTGCTAATATAGCTAATGGTGAAGACCATAA
TGAAATAAAAAGCGAGCATTTACTTCTTGCATTATTAAAACAAGAGGACGGACTTATTCAGCCTTTAGTAGAAAGAATAG
GCGTTCCTATAAATACGTTAATAGATAAAACTCAAAGATTAGTTGATGAAAATGTAAAGGTAACAGGAGAAAATGTGCAG
TTACATCTATCTACTAATGCTGGTAAAGTTTTAGCAAAAGCAGAAAAAGAAGCTAGTGCTTTAAAAGACCAATATGTATC
AACAGAGCATATATTCTTAGCACTCGTTGAAGCTGACAACAAAGCAGGCGACATGCTTAGAAAAAGCGGAATAAGTAAAA
AAGAAGTTTTAAGTGCATTAAAAGATTTAAGAAAAGGTCAAAGTGTAAATAGCCAAGACCCAGAAGCTAAAATGCAGGCA
CTTGATAAATACTGCCGTGATTTAACAGCATTAGCAGAAGCAGAAAAAATTGACCCTGTTATAGGACGTGATGAAGAGAT
AAGACGTGTTATGCAGGTGTTGTCAAGAAGAACTAAAAATAACCCTGTGCTTATAGGTGAGCCTGGTGTTGGTAAGACTG
CTATTGTTGAAGGACTTGCAAGAAGAATAGTTTCTCAAGATGTACCTGAGGGACTTAAAGATAAAAGGCTATTAGCTTTA
GATTTAGGTGCATTAGTAGCTGGTGCAAAATTCAGAGGAGAGTTTGAAGAGAGACTAAAAGCTGTTATCACAGAGATAGA
AAAATCTGAAGGAAGCATTATATTATTTATAGATGAGCTTCACACACTTGTAGGAGCTGGTGCTACAGAGGGAGCAATGG
ACGCTTCTAACCTATTAAAACCTGCATTAGCAAGAGGCGAATTAAGAGCAATAGGTGCTACTACTTTAGATGAATATAGA
AAATATATTGAAAAAGATAAAGCACTTGAGAGAAGATTCCAACAAGTTTATTGTAAAGAGCCTAGCGTTGAAGATACTAT
TTCAATACTTAGAGGTTTGAAAGATAAATACGAAGTTCATCATGGTGTAAGAATAAAAGACGATGCATTAGTTGCTGCTG
CTGTTTTATCTAACAGGTATATAACTAATAGATTCTTACCTGATAAAGCTATTGACTTGGTAGATGAAGCTGCAAGCCAA
TTAAAAATAGAAATAGACAGTCAGCCTACTGAACTTGATAAAATTGAAAGAAAGATTTTACAGCTTAATATAGAAAAACA
AGCTCTTTCAAAAGAAAATGATGCAGCATCTAAAGAAAGATTAGAAAAACTTGAAAAAGAATTATCTGAACTTTCTGAAG
AACGTAATGCTATGAAACTTCAATGGGATAATGAAAAAGGAAGAATTGAAGAGACTAGAAAATTAAAAGAAGAACTTGAA
GCTTTAAATATAAAAGAGACTCAATATACAAGAGAAGGTAATTTAGCAAAGGCTGCTGAAATAAAATATGGTAAAATACC
AGAACTTCAGAAAAAATTAGAAGAAGCAACTAAAGCTATGGAAGAAGCTAAAAACTCTGACAAGAAAGGTCTTTTAAGAG
AAGAGATTTCTGAAGATGATATAGCTAGAGTAATATCTGTATGGACTGGAATACCTGTAAGTAAAATGCTTACAAGCGAA
AAACAAAAATACTTACAGCTTGAAGAAGTATTACATAAGAGAGTTGTAGGACAAGATGAAGCAATCACTTCAGTTGCTGA
TGCCATAAGAAGAAACAGAGCAGGACTTTCTGATGAAAACAAACCTCTTGGAAGTTTCTTATTTATAGGACCTACTGGGG
TTGGTAAAACAGAGCTTGCTAAAACACTTGCTGATTTCTTGTTTAGCGATGAAAAAGCTTTAACAAGAATTGATATGAGT
GAATATATGGAGAAGTTTTCTGTTACTAGACTTATAGGAGCTCCTCCAGGATATGTAGGTTATGATGAGGGAGGACAATT
AACAGAAGCCGTTAGAAGAAGACCTTATTCTGTTATACTATTTGATGAGATAGAAAAAGCTCACCCTGATGTATTTAATG
TTTTACTTCAGGTATTAGATGACGGAAGACTTACTGACGGACAAGGAAGAATAGTAGATTTCAAAAATGCTATTATCATA
ATGACAAGTAATTTGGGTTCTGACCTTATTCTTGAAGCTAATGATACTAATGATATCAAAGAAAAAATTCAAGAGTTACT
AAAAATGTCATTTAGACCAGAGTTCTTAAACAGAATAGATGAGATAATAACATTTACTAGACTTGACAAAAAATACATTG
CTGAGATAGTAAGAAATCAAATAGCAAGAGTTGCTAACAGACTTAAAGATAGAAGAATAACTTTAGATGTAAGCGATGAA
GCTATAGACTATATTGCTGATATTGGTTATGACCCTCAGTTTGGAGCAAGACCATTAAAAAGAGCAATACAGAATTATAT
AGAAAACCCACTAGCTAAAGAAATGTTAGCAGGAAAATATTTAGAAGGAGATACTATAAAGGTAAAAAAATCAGGAGACG
GTTTGGTTTTTGAAAAATAA

Protein sequence :
MDYNKYTIKAQEAVNEAANIANGEDHNEIKSEHLLLALLKQEDGLIQPLVERIGVPINTLIDKTQRLVDENVKVTGENVQ
LHLSTNAGKVLAKAEKEASALKDQYVSTEHIFLALVEADNKAGDMLRKSGISKKEVLSALKDLRKGQSVNSQDPEAKMQA
LDKYCRDLTALAEAEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSQDVPEGLKDKRLLAL
DLGALVAGAKFRGEFEERLKAVITEIEKSEGSIILFIDELHTLVGAGATEGAMDASNLLKPALARGELRAIGATTLDEYR
KYIEKDKALERRFQQVYCKEPSVEDTISILRGLKDKYEVHHGVRIKDDALVAAAVLSNRYITNRFLPDKAIDLVDEAASQ
LKIEIDSQPTELDKIERKILQLNIEKQALSKENDAASKERLEKLEKELSELSEERNAMKLQWDNEKGRIEETRKLKEELE
ALNIKETQYTREGNLAKAAEIKYGKIPELQKKLEEATKAMEEAKNSDKKGLLREEISEDDIARVISVWTGIPVSKMLTSE
KQKYLQLEEVLHKRVVGQDEAITSVADAIRRNRAGLSDENKPLGSFLFIGPTGVGKTELAKTLADFLFSDEKALTRIDMS
EYMEKFSVTRLIGAPPGYVGYDEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRIVDFKNAIII
MTSNLGSDLILEANDTNDIKEKIQELLKMSFRPEFLNRIDEIITFTRLDKKYIAEIVRNQIARVANRLKDRRITLDVSDE
AIDYIADIGYDPQFGARPLKRAIQNYIENPLAKEMLAGKYLEGDTIKVKKSGDGLVFEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 9e-98 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BPP43_04650 YP_007234457.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2084 Protein 2e-105 42