Gene Information

Name : BPP43_00335 (BPP43_00335)
Accession : YP_007233686.1
Strain : Brachyspira pilosicoli P43/6/78
Genome accession: NC_019908
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 68813 - 70246 bp
Length : 1434 bp
Strand : +
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGAGAAAAACAAAAATAATAGCAACTTTAGGACCTAGATGGTCTAATGAAGAAATGGTAAAAAAGATAATAGAGAATGG
CGCTAATGTATGCAGGCTTAATTTTTCATTTGGAAGCTATGATGAACATTTAGAGAGAATAAACATAATAAGAAAAGTTT
CTGATGAGTTGGGTAAACCTGTAGCTATATTAGCAGATTTGCAGGGACCTAAAATAAGAATAGGTAAGCTAAAAGAGAAT
ATCACTGTAAAAGAAGGCGACATTGTAAAATTAAGCGGACATAAAGAAACTAATGATGAAAGCATAATACCTACTACGCA
TGAAAACATTGCTCATGATGTAAAGAGCGGTTCATTGCTTTTGATAGCTGACGGTACTATACAGCTTATAGTGGAATCTA
GTGATGAGGCTTCAAAACTTGTTGTATGTAAGGTTATAACTGGAGGTACTATATTAAGCAGTAAGGGTATTAATTTGCCT
GGTGCTCATGTAACAACAGAAGTTTTAACAGAAAAAGATGTTAGTGATGCTTTATTTGCTGCTAAAAACGGTGCTAATTA
TTTGGGTATGAGTTTTGTAAGAAGAGCAGAAGATGTTATAAGACTTAGAAAGATATTAGATGATAATAATTTTCAGCATG
TTGGAATTGTGTCAAAAATAGAAAATACAGAATCATTAGAAAATTTGGAAAGTATAATAAAAGTGTCTGATGGTGTAATG
GTGGCAAGAGGAGACTTGGGAGTAGAGATACCATTTGGAGAGGTTCCTGTTTGGCAGAAGAAGATACTAAAAATGGCAAA
CGATATGGGTAAGATTACAATAATAGCTACCCAAATGCTTGAGAGTATGACAAAAAGCCCTGTTCCTTCAAGGGCAGAGG
CTAGCGATGTTGCTAATGCTGTATTAGACGGTACTGATGTTGTGATGATGTCTGCTGAGACTGCTTCGGGAGATTATCCT
ATAGAGTCTGTTAAGGCTATGGTTTCTATAGTAGAGGCTGCTGAGAAATCTGTTAATAAAACTTCTCATGACAATATGAC
TTATTTAGACAGCGGAGTTAATGATGCTTTGGCTGATAGTGCTTCTTATTTATCATATAGTTTAGATAATAAGGCGATAA
TAGCTCTTTCAAGGTCTGGAAGAACAGTTAGAAATCTATCTAAAAAAAGACCAAAAACTCCTATAGTATTTATGTCTGCT
GATAGTAATCTTTGTAATGGTCTTGCTATATGTCATAATGTTTATACTATACATATGCCTGAAGATTTGAATTTTAGTGC
TGGTATTAACCATGGAGGCGAGATTAACATACTTGAAGATACTTTGGTAGAGCATAAATTAGCAGAACATGGCGACAGAA
TAATAGTAGTGAGCGGCAGCAAATGGCAGGGTAGGTGGCAAGAGAATAGCGTTCGTATAGTAGTTATGCACTAA

Protein sequence :
MRKTKIIATLGPRWSNEEMVKKIIENGANVCRLNFSFGSYDEHLERINIIRKVSDELGKPVAILADLQGPKIRIGKLKEN
ITVKEGDIVKLSGHKETNDESIIPTTHENIAHDVKSGSLLLIADGTIQLIVESSDEASKLVVCKVITGGTILSSKGINLP
GAHVTTEVLTEKDVSDALFAAKNGANYLGMSFVRRAEDVIRLRKILDDNNFQHVGIVSKIENTESLENLESIIKVSDGVM
VARGDLGVEIPFGEVPVWQKKILKMANDMGKITIIATQMLESMTKSPVPSRAEASDVANAVLDGTDVVMMSAETASGDYP
IESVKAMVSIVEAAEKSVNKTSHDNMTYLDSGVNDALADSASYLSYSLDNKAIIALSRSGRTVRNLSKKRPKTPIVFMSA
DSNLCNGLAICHNVYTIHMPEDLNFSAGINHGGEINILEDTLVEHKLAEHGDRIIVVSGSKWQGRWQENSVRIVVMH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-65 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-64 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-65 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-65 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BPP43_00335 YP_007233686.1 pyruvate kinase VFG0479 Protein 3e-65 43