Gene Information

Name : BPP43_06170 (BPP43_06170)
Accession : YP_007234731.1
Strain : Brachyspira pilosicoli P43/6/78
Genome accession: NC_019908
Putative virulence/resistance : Virulence
Product : hemolysin B
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1300127 - 1302631 bp
Length : 2505 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTCTTATCCATTTCGTCTTACTAATAAAGCTATAAGAATATTAGACTTACACTCTGTGGAAGAAGCTAAGAGATTAAA
TCATGATATGCTTACTCCAGAGCATGTTTTATTAGGAATATTTCATGAAACTGATTCAATAGTTGTGAATGTTTTAAATA
AATTAAAAATAGATATAGAAAAAATTAAATTTGATATAGAATCTTCTATGGTAAAATCTACAAGCAACACTAAATTGTTT
GGTAAGATACCTCCATCACCACGCATTCAGCATTTAATAAGCAGAGCGGCAGAAGAGGCTAAATCATTAGGAGATAATTG
CATAAGCACAGAACATTTACTTCTTGGTATTTTAAAAGAGGAAAATGGAATAGCATATAATGTACTTACTAGCTATAATT
TAGATTTAAAAACATTAAGACATGAGATGATGAGAATTAGAGGTAAATCTGGTTCTTCATCAAATATTTCTGAATCTTCT
TCTAGCACTATTCAAGAAGATAACACAGCAAGAACTCCTACTTTAGATAAGTTTGCCCGTGATTTAACTAAAATGGCTAG
AGAAAAGGCTTTAGATAGAGTGATAGGCAGAGAAAACGAGGTAATGAGAGTTGTACAGATACTTTCAAGGAGAAAGAAAA
ATAACCCTATACTATTAGGAGAGCCTGGTGTTGGTAAGACTGCTATAGTTGAGGGGTTGGCTGAAAAGATTGTTTCTACT
GATGTGCCTGATATATTATTAAAAAAGAGAGTTTTGAGTTTAGATTTATCTTCTGTTGTTGCTGGTACTAAATATAGAGG
TGAGTTTGAAGAGAGAATAAAAAACATAGTAATGGAGATAAAGAAAGTTGGCAATATTATAATATTTATAGATGAGCTTC
ATACTTTAATTGGAGCAGGAGGAGCAGAGGGAGCTTTAGATGCTGCTAATATGCTTAAGCCTGCACTTTCACGCGGAGAG
ATTCAATGTATTGGTGCAACTACAATTAATGAATATAAAAAATATATAGAAAAAGATGGTGCTTTGGTGAGAAGATTTCA
GCCTATAAATGTTGAAGAGCCTTCTATTGAAGATACTATAGAAATATTAAATGGAATAAAATCTAAATATGAAGAGCATC
ATAAAGTAAAATATACTGATGGGGCTATTTATGCTTCTGCTGTATTAAGTAAAAGATATATATTTGAAAGACATTTACCA
GATAAGGCTATAGATTTAATTGATGAGGCAGGTTCGAGAGCAAGACTTATGAATATGGTAAGACCTCAGGAATTAAAAGA
TTTAGAAAATAAAATAAAAGAGCTTAATCAAGAAAAAGAGACTGTTGTAAAAAATCAGAATTTTGAAGAGGCTGTTAAAT
TAAGAGATGCTATAAAATCTTTACAAGAGGAATTGGATAAAAAAGAAGCTGAGTGGAGAAGCGAAAGAGACAAAACAGAA
ACAATTATTAATGAAGATGATATAAGACATGTAATATCAGAAATTACAAATATACCAGTAAAAAGATTATTAGATTCTGA
GAGTAAAAGACTTATTGGTATGGAAGATGAACTTCACAGTAAGATAGTAGGTCAGAAAGAGGCTATATCATCTATATCAA
AAGCTATAAGAAGAGCAAGAGCCGGATTAAAAAGTACTAAAAAACCGCTTGGAAGTTTTATATTTTTAGGTCCTACTGGT
GTTGGTAAGACGGCTTTAGCTAAAGTACTTTCAGAGTTTATGTTTGGAGATAGTGATGCTCTTATAAGAATAGATATGAG
TGAGTTTATGGAGAAGTTTGCAGTAAGCAGACTTATTGGAGCTCCTCCTGGATATGTTGGATATGAAGAGGGAGGCGGAC
TTACAGAGAAGGTGAGAAGAAAACCTTATTCTTTAATACTTTTTGATGAAATAGAAAAAGCTCACCCCGACATCACAAAC
ATACTTTTACAGGTGCTTGAAGAGGGGCAGCTTACAGATAACTTTGGAAGAAAGGTTGATTTCTCTAATACTATAATTAT
TATAACAAGCAACTTGGGTGCAAGAGATATTGTTAAAGGAACTTCTTTAGGTTTTAATGCCATTGGAAGTGAAAAAGATA
TTAATGACATGAAAAACTTTGCTATGGAAGAATTGAAGCAGAATTTCAATCCAGAGTTTTTAAACAGAATAGATGATATT
ATAGTATTCCATACTCTTACAAAAGAAGATTTGAAAGATATTATAGAGATTATGCTTAGAGAGTTGAATGAAGCTATAAA
AGATAGAAATATTTTTATAAGTTTAACTGATGATGCAAAAAATTATATAATAGATAAAGGCTTTGACAAGAAATATGGTG
CAAGAAGTTTAAGACGTGCTATACAAAAAGAGGTTGAAGATTATATTAGTACGGAGATACTTTTCGGGCATATTGAAGAG
GGCGATAATATAAATGTTGATTCTGATGGGCAGTCGCTGCTATTTAATGTTGAAAAGGTAAAGACCTACAGAGAAAATGA
GGTAGAAGAGTTATCTAAGAGTTGA

Protein sequence :
MSYPFRLTNKAIRILDLHSVEEAKRLNHDMLTPEHVLLGIFHETDSIVVNVLNKLKIDIEKIKFDIESSMVKSTSNTKLF
GKIPPSPRIQHLISRAAEEAKSLGDNCISTEHLLLGILKEENGIAYNVLTSYNLDLKTLRHEMMRIRGKSGSSSNISESS
SSTIQEDNTARTPTLDKFARDLTKMAREKALDRVIGRENEVMRVVQILSRRKKNNPILLGEPGVGKTAIVEGLAEKIVST
DVPDILLKKRVLSLDLSSVVAGTKYRGEFEERIKNIVMEIKKVGNIIIFIDELHTLIGAGGAEGALDAANMLKPALSRGE
IQCIGATTINEYKKYIEKDGALVRRFQPINVEEPSIEDTIEILNGIKSKYEEHHKVKYTDGAIYASAVLSKRYIFERHLP
DKAIDLIDEAGSRARLMNMVRPQELKDLENKIKELNQEKETVVKNQNFEEAVKLRDAIKSLQEELDKKEAEWRSERDKTE
TIINEDDIRHVISEITNIPVKRLLDSESKRLIGMEDELHSKIVGQKEAISSISKAIRRARAGLKSTKKPLGSFIFLGPTG
VGKTALAKVLSEFMFGDSDALIRIDMSEFMEKFAVSRLIGAPPGYVGYEEGGGLTEKVRRKPYSLILFDEIEKAHPDITN
ILLQVLEEGQLTDNFGRKVDFSNTIIIITSNLGARDIVKGTSLGFNAIGSEKDINDMKNFAMEELKQNFNPEFLNRIDDI
IVFHTLTKEDLKDIIEIMLRELNEAIKDRNIFISLTDDAKNYIIDKGFDKKYGARSLRRAIQKEVEDYISTEILFGHIEE
GDNINVDSDGQSLLFNVEKVKTYRENEVEELSKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BPP43_06170 YP_007234731.1 hemolysin B VFG0079 Protein 0.0 51
BPP43_06170 YP_007234731.1 hemolysin B VFG0080 Protein 5e-143 51