Gene Information

Name : Desdi_1473 (Desdi_1473)
Accession : YP_007220364.1
Strain : Desulfitobacterium dichloroeliminans LMG P-21439
Genome accession: NC_019903
Putative virulence/resistance : Resistance
Product : D-alanine--D-alanine ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.2.4
Position : 1499921 - 1501006 bp
Length : 1086 bp
Strand : +
Note : PFAM: D-ala D-ala ligase N-terminus; D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase

DNA sequence :
ATGGATACGATGATTAATTCCTCAAACATGAAAGGAGAAAGCAGTATGAATCGATTGAAAATCGCCATTATCTTCGGAGG
TTGTTCTGAAGAACATTCCGTTTCCGTTAAATCTGCCCAAGAGGTCGCTAAAAACCTTGATCTCGAAAAGTATGAGCCCT
ACTATATCGGAATTACGCAAAATGGTGTCTGGAAGCTTTGTCACTTCCCTGAAGCAAATTGGGAAAATAGTTGTTGTCTT
CCGGCTATGCTGGCACCGGACAGTGGGGTACACGGCTTGATTGTTTTGGAGCAGGGAAAATACAAGATGATACCTTTGGA
TATGGTGTTTCCTGTTCTGCATGGCAAATTTGGCGAGGATGGTGCCATACAAGGTTTGTTGGAGCTTTCCTGCATCCCAT
ATGTAGGCTGCGATATCCAAAGTTCTGCTCTGTCTATGGACAAATCCCTTGCTTATATCGTCGCCGGAAACGCGAGAATT
GCGACCCCGAATTTCTGGACGTTTACGGAGAACGAGGATATGGACCCCGACCGGTTTATTTACCCCGTTTTTGTTAAGCC
GGCCCGTTCGGGGTCATCTTTTGGGGTTACTAAGGTATGCCGAGAAGAAGAATTGCTAAGTGCGGTGGAAATCGCCAGAC
AGTATGATTCGAAGGTGCTGATTGAAGAGGCTGTCGTCGGTAGTGAGGTAGGATGTGCGATATTTGGGGACGATCCGGAT
TTGACTGCAGGAGAAGTAGATCAAATTTCACTATCGCATGGTTTTTTTAGAATCCATCAGGAGAGTGAGCCTGAAAACGG
TTCCGAAAACTCAACAATCATCGTTCCCGCTGATATTTCGACGGAGATGCGCTTGCATATCCAGGAGACGGCTAAAGCCA
TCTATCGTGCTTTGGGATGCAGGGGACTGGCGCGAGTGGATATGTTTCTGAAGGAAGATGGGGAAGTAATTCTAAACGAG
GTAAATACGTTGCCTGGAATGACCTCGTACAGCCGTTTTCCGAGAATGATGGCAGCCGCAGGGCTAACTTTTGCCGAAGT
GATCGACCGAATCGTTGCATTAACCTTGGAAGGGAAAAGACGATGA

Protein sequence :
MDTMINSSNMKGESSMNRLKIAIIFGGCSEEHSVSVKSAQEVAKNLDLEKYEPYYIGITQNGVWKLCHFPEANWENSCCL
PAMLAPDSGVHGLIVLEQGKYKMIPLDMVFPVLHGKFGEDGAIQGLLELSCIPYVGCDIQSSALSMDKSLAYIVAGNARI
ATPNFWTFTENEDMDPDRFIYPVFVKPARSGSSFGVTKVCREEELLSAVEIARQYDSKVLIEEAVVGSEVGCAIFGDDPD
LTAGEVDQISLSHGFFRIHQESEPENGSENSTIIVPADISTEMRLHIQETAKAIYRALGCRGLARVDMFLKEDGEVILNE
VNTLPGMTSYSRFPRMMAAAGLTFAEVIDRIVALTLEGKRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanB NP_815951.1 D-alanine--D-lactate ligase Not tested Not named Protein 2e-104 65
vanB YP_008394259.1 Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase Not tested Not named Protein 3e-106 65

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase U00456.gene.p01 Protein 1e-104 65
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase NC_014475.1.orf3.gen Protein 2e-107 65
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase U35369.1.gene6.p01 Protein 1e-104 65
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase AE016830.1.gene2250. Protein 1e-104 65
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase NC_005054.2598280.p0 Protein 2e-107 65
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase AF310956.2.orf5.gene Protein 2e-105 65
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase AY145441.gene.p01 Protein 1e-105 65
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase AF277571.gene.p01 Protein 1e-109 64
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase AY489045.gene.p01 Protein 1e-105 63
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase AF130997.1.orf4.gene Protein 8e-110 63
Desdi_1473 YP_007220364.1 D-alanine--D-alanine ligase AF162694.gene.p01 Protein 7e-53 41