Gene Information

Name : Theco_0080 (Theco_0080)
Accession : YP_007211333.1
Strain : Thermobacillus composti KWC4
Genome accession: NC_019897
Putative virulence/resistance : Resistance
Product : heavy metal-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 93361 - 95307 bp
Length : 1947 bp
Strand : -
Note : PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-transloc

DNA sequence :
TTGAAACCTTCTTCATTCGGCACTGCAGAAGGTCTGATCAATGAACAGGCATCCGTTTATTCTTCTTCCAGCAAGACAAA
GGCATATGACTTGTTCAAACGATATGCCGAGGGCATCGCCGCTTTGACAAGCGGCATTCTGATTGCTCTCGCCTGGGGAA
TCGGGCATGTTTCCCATGCAGGGTCTGTCGCCATTTACCTGCTTGCTTTTGCTGTTGGCGGATTTGTCAAAGCGAAAGAA
GGGCTGCATACACTCATCGCAGAGCGGGATCTTGACGTAAATTTACTCATGATTGTGGCGGCCATTGGTGCTGCCAGTAT
CGGTTATTGGACAGAAGGAGCCGTGCTGATTTTTATTTTTTCATTAAGTGGTGCTTTGGAAAGTTACACAATGGAGCGCA
GTCGTCGGGATATTTCTTCCCTTATGGATTTAAAGCCGGAGACGGCCATACGTTACCAAGATGGTACGGAAACCATTGTT
GCCGTTGAACAGTTAGAGGTGGGCGACCTTGTATTGGTGAAACCCGGTGAGCGCATCCCCGCTGACGGCATCGTGAAAGA
AGGAACATCCGCCGTCAATCAAGCATCCATCACGGGGGAATCCATTCCGGTGGATAAAACGGCCGGGGATGATGTATTCG
CAGGTACGTTAAATGGCCAAGGGGCGCTACTCATAGAAGTCACGCAGCCCAGTAATTCGACTTTGTTTGCCAAGATCATT
CGTTTGGTTCAAGAGGCACAAAGCGAGAAACCGGCTTCACAAATGTTCATCGAGCGTTTTGAACGCATTTATGCGAGAAG
CATCATTTTGGCGACGCTTTTGCTGATTGCCGCTCCGCCTTTTCTTCTCGATTGGTCGTGGAAACAGACGCTGTATAAAG
CGATGGTTTTCCTCGTCGTCGCTTCTCCGTGCGCGTTAGTTGCATCGATCATGCCGGCTATGCTGTCCGCCATTTCCAAC
AGCGCGAGAAAAGGACTGCTTTTTAAAGGGGGGGCGCATCTTGAAAACCTTGCCCGGATTAAAGTCATCGCATTCGATAA
GACAGGAACGCTGACGAACGGCCGTCCCATAGTGACAGATCTTATTGCCTTCCAGGGGTATACAGAAACCGAAATGCTGC
AAGCAGCGGCTTCCATTGAGAGCTTGTCCGAACATCCGCTTGCCAAAGCCATTGTGCAAAAAGCAAAAGAGCAAGGGCTC
CCGCTTGAACGGCCGACTGAACTTCAGGCTCTGACAGGATGGGGCGTACAGGCGGAATGGAAAGGGGAAACATGGAGAAT
TGGGAAGCCGACCATGTTGGGACATGATTTATTAACTGCGGAATTAGATTCTGTGATCGATCGGCTGGAGCAGCAGGGAA
AAACCGTAACGGTCATTCACAATTCTCATACCGTGGTTGGCATTATCGCACTGCAGGACAGTATTCGCGCGCAGGCGAAA
CAAGCCATCGCCGAGATTAAAAAACTCGGCATCGAAGTCGTGATGTTGACCGGGGATCAGAAAAGAACTGCCCAAACGAT
TGCCCGTGAAGCCGGGATTCATTTGGTGTATTCCGAATTGCTGCCTGAAGATAAGGTGAATCGCATTAAGGACTTGAAAC
GAACGTATGGCCAAGTAGCTATGGTAGGCGATGGAGTGAACGACACGCCTGCTTTAGCGGCGGCGACAGTAGGCATCGCG
ATGGGCGGGACAGGAAGCGATGCCGCCCTTGAAACAGCAGATCTTGTCCTCATGAACGACGACATTGAGAAAATCGCCGC
GGCGATTGCACTTGGAAAACGAACGAAAACGGTCGTGAAACAAAATATGATATTTGCCATTGCGGTGATTGCCTGCTTAA
TTACGGCGAACTTTATCTCGGGTATCGCGTTGCCGCTTGGCGTGGTTGGGCATGAAGGAAGCACCATTCTCGTCATTTTG
AATGGGTTGCGGTTATTACGTGGATAA

Protein sequence :
MKPSSFGTAEGLINEQASVYSSSSKTKAYDLFKRYAEGIAALTSGILIALAWGIGHVSHAGSVAIYLLAFAVGGFVKAKE
GLHTLIAERDLDVNLLMIVAAIGAASIGYWTEGAVLIFIFSLSGALESYTMERSRRDISSLMDLKPETAIRYQDGTETIV
AVEQLEVGDLVLVKPGERIPADGIVKEGTSAVNQASITGESIPVDKTAGDDVFAGTLNGQGALLIEVTQPSNSTLFAKII
RLVQEAQSEKPASQMFIERFERIYARSIILATLLLIAAPPFLLDWSWKQTLYKAMVFLVVASPCALVASIMPAMLSAISN
SARKGLLFKGGAHLENLARIKVIAFDKTGTLTNGRPIVTDLIAFQGYTETEMLQAAASIESLSEHPLAKAIVQKAKEQGL
PLERPTELQALTGWGVQAEWKGETWRIGKPTMLGHDLLTAELDSVIDRLEQQGKTVTVIHNSHTVVGIIALQDSIRAQAK
QAIAEIKKLGIEVVMLTGDQKRTAQTIAREAGIHLVYSELLPEDKVNRIKDLKRTYGQVAMVGDGVNDTPALAAATVGIA
MGGTGSDAALETADLVLMNDDIEKIAAAIALGKRTKTVVKQNMIFAIAVIACLITANFISGIALPLGVVGHEGSTILVIL
NGLRLLRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 7e-103 43
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 3e-88 42
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 3e-88 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-106 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-106 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theco_0080 YP_007211333.1 heavy metal-translocating P-type ATPase BAC0092 Protein 4e-140 52
Theco_0080 YP_007211333.1 heavy metal-translocating P-type ATPase BAC0099 Protein 2e-97 44
Theco_0080 YP_007211333.1 heavy metal-translocating P-type ATPase BAC0124 Protein 9e-102 44