Gene Information

Name : Theco_2616 (Theco_2616)
Accession : YP_007213708.1
Strain : Thermobacillus composti KWC4
Genome accession: NC_019897
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2725426 - 2727180 bp
Length : 1755 bp
Strand : -
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGCGCAAAACGAAGATCGTATGCACCATCGGTCCCGCAAGCGAATCACTCGAGAACACGAAGAAACTGATCCTGGCGGG
CATGAACGTCGCGAGGCTGAACTTCTCCCACGGCGATTTCGAGGAACACGGCAACCGGATCAAGAACATCCGCCAGGCTT
GCCGCGAACTGGGCAAGACCGTCGCCATCCTGCTCGACACCAAGGGTCCGGAGATCCGCCTCGGCAATCTGGCCGAAGAG
CCGGTCGAGCTCGTGGCGGGCGAGTTCGTGACGCTGACGACGGAGAACATCCTCGGCGACAGGCACCGCATCCCGGTGAC
GTACAGCGACCTTCCCCGGGACGTGAAGGTCGGGGACACCATTCTGCTCGATGACGGCCTGATCGGCCTGAAGGTTGTTG
AGATCCAGGGCACCGAGATCAAGTGCGAGATTCAGAACAGCGGCCCGATCAAGAGCAAGAAGGGCGTCAACGTTCCGGGC
GTTGCCATTTCGCTGCCTGGCATCACGGAGAAAGACGCCAACGACATTCTTTTCGGGATCGAGCAGGGCATTGACTTCAT
TGCGGCATCGTTCGTGCGGAGAGCAAGCGACGTGCTGGAAATCCGCGAACTGCTGGAACGGCACAACGCGTCGCATATTC
AGATCATTGCCAAGATTGAAAACCGCCAGGGCGTCGACAATCTGGACGAAATACTTGAAGTGGCGGACGGCCTGATGGTG
GCGCGCGGCGACCTTGGCGTCGAAATTCCGGTCGAGGAAGTGCCGCTCGTGCAGAAAATGATGATCGAGAAATGCAACCG
CGCCGGCAAACCGGTCATCACGGCGACGCAGATGCTCGATTCGATGCAGCGCAACCCGCGGCCGACCCGCGCGGAAGCGA
GCGACGTCGCGAACGCCATCTTCGACGGCACCGACGCGATCATGCTGTCGGGCGAGACGGCGGCCGGCAAATATCCGGTT
GAATCGGTCATGACGATGGCGCGCATTGCGGAGCGGGCGGAAGCTGCGCTTGAATATCGGGAGATTTTCCTCCGCCAGGC
GAGCGCCCAGCAGACGACCGTGACGGAAGCGATCAGCCAGGCGGTCGCGAACTCCGCGCTCGATCTGGATGCGGATGCGA
TCATCACTTCGACGGAGAGCGGCTATACGGCGCGGATGGTGTCGAAATATCGTCCGAAGGCGCCGATTATCGCCGTCACG
CCGGTCGAGCACGTCATGCGCAGCCTGCAGCTTGTCTGGGGCGTCATTCCGGTGCTCGGCAAGCCGGCGAAGACGACGGA
CGAGATGTTCGACATCGCCGTGAACGGCGCCGTCGAATCCGGTCTCGTCAAGCTCGGCGACACGGTCGTCATCACGGCCG
GCGTGCCGGTCGGACGTTCCGGATCGACGAACCTCATCAAGATTCATACGGTCGGCGATCTCGTCGCCAAGGGCCAGGGG
ATCGGCAGCCAGTCCGCGACCGGCAAGGTCGTCGTCGCGAACACGCCGGAAGAAGCGATCGCCAAGGCGAAGGAAGGCAT
GATTCTCGTTACGCCTTCGACGAACCGCGAATACATGCCGGCCATCGAGAAAGCGGCGGCGCTGATCACGGAGCAGGGCG
GCATTACGAGCCACGCGGCCGTCGTCGGCCTGAACCTCGGCATCCCGGTCGTGCTCGGCGTGTCCGATGCGACGAAACGG
ATGTCGGACGGGATGGAAGTGACGGTCTACGCCGAGATCGGCGTCATCTATACGGGACAGGCGCGCGTGCTGTAA

Protein sequence :
MRKTKIVCTIGPASESLENTKKLILAGMNVARLNFSHGDFEEHGNRIKNIRQACRELGKTVAILLDTKGPEIRLGNLAEE
PVELVAGEFVTLTTENILGDRHRIPVTYSDLPRDVKVGDTILLDDGLIGLKVVEIQGTEIKCEIQNSGPIKSKKGVNVPG
VAISLPGITEKDANDILFGIEQGIDFIAASFVRRASDVLEIRELLERHNASHIQIIAKIENRQGVDNLDEILEVADGLMV
ARGDLGVEIPVEEVPLVQKMMIEKCNRAGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGKYPV
ESVMTMARIAERAEAALEYREIFLRQASAQQTTVTEAISQAVANSALDLDADAIITSTESGYTARMVSKYRPKAPIIAVT
PVEHVMRSLQLVWGVIPVLGKPAKTTDEMFDIAVNGAVESGLVKLGDTVVITAGVPVGRSGSTNLIKIHTVGDLVAKGQG
IGSQSATGKVVVANTPEEAIAKAKEGMILVTPSTNREYMPAIEKAAALITEQGGITSHAAVVGLNLGIPVVLGVSDATKR
MSDGMEVTVYAEIGVIYTGQARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-103 53
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-102 53
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-102 53
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-103 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theco_2616 YP_007213708.1 pyruvate kinase VFG0479 Protein 2e-103 53