Gene Information

Name : Theco_1647 (Theco_1647)
Accession : YP_007212779.1
Strain : Thermobacillus composti KWC4
Genome accession: NC_019897
Putative virulence/resistance : Resistance
Product : copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1728900 - 1731062 bp
Length : 2163 bp
Strand : -
Note : PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy

DNA sequence :
ATGGCACGACATGCTGCGCCGGAGTCCGGCATCACGAAGGTTTACCGCGTGGAAGGGTTCACCTGCGCGAACTGCGCGGG
CAAATTCGAGGAGAATGTGAAGCGGCTCCCGGGCGTGCTGGACGCGAAGGTCAATTTCGCCGCGGCGAAAATTACCGTTA
CGGGCGAGGCGACGATCGCGGAGCTGGAAAAAGCCGGCGCCTTCGAACGATTGAAAGTGCGGCCCGATACCGGGGACATC
GCAACGGGCGGCAACTCCGGCAAGGCGCGCGGGGCGGCGGCGTTCCTCAGGCGGCACGGCAGCCTGCTCGCGGGCGCGGC
GCTTCTTGCCGCCGGCTGTCTGGCCCGGCTGGCGCTCGGCGGCCATCATCCGGTGACCGCGGCGGCATTCGCGGCGTCCA
TCGTCGTCGCCGGGCATCGGCTTTTCCGGACCGGTCTCAACAACCTGATCCGCCTCGACTTCGACATGCGGACGCTGATG
ACCGTCGCGATCATCGGCGCGGCGCTGATCGGCGAATGGACGGAAGGCGCCGTCGTCGTCATCCTGTTCGCGCTCAGTGA
AGCGCTCGAACGCTACTCGATGGAGCGCGCCCGCCGGTCGATCCGCAGCCTGATGGAGCTGGCGCCGCGCGAAGCCCCCG
TGCTGCGGGACGGCCGGGAAATGACGGTGCGAACGGACGAGATCGAAGTCGGCGACACGCTCATCGTGCGGCCGGGCGCA
AAGATCGCGATGGACGGGATCGTTGCATCCGGCACCTCCGCAGTCAACCAGGCCGCGATTACGGGCGAATCTGTTCCGGT
GCCGAAATCGCCCGGCGACGAAGTGTTCGCGGGCACGCTGAACGGGGAAGGCCTGCTCCACGTGCGCGTTGCGCGGCTGG
CGCAAGATTCGACGATCTCGCGGATTATCCGCCTGGTCGAAGAAGCGCAGGAAGGGCGCGCGCCGGCGCAGGCGTTCGTG
GACAAGTTCGCCAAGTATTACACGCCCGTCATCATCGCCGCTGCGGCGCTGATTGCGGTCGTACCGCCCCTGATCTCCGG
CGGCGGATGGCTTGACTGGCTCTACCAGGGGCTCGCCGTACTCGTCGTCGGCTGCCCGTGCGCGCTCGTCATCTCGACGC
CGATCGCAATCGTCTCCGCCATCGGCAGCGCCGCGGGCCGGGGCGTGCTGATCAAAGGCGGCATCCATCTGGAGCAGCTC
GGCGCGGTGAAGGCGATCGCTTTCGACAAGACCGGCACGGTCACGCAAGGGATTCCGAGGCTGACCGATGTCCGGCTGTT
CGGCGAATCGGTTGACCGCCGGGATTTGCTCAGGATAGCCGCCGCGCTCGAACATCGCTCCGGACACCCGCTCGCTGCGG
CCGTCACGGGGGCGGCCCGTGAGGAAGGCATCGATTTCCCGGGTACAATCGTGGACAACTTCACGTCCGTGACAGGCCGG
GGAATCGAGGGCGAAACGGAAGGCGCGCGTTACCGCATCGGCAGCCCGGAATGGATCCGGATCGGGACGGACGCGCGGAT
GGAAGGCGAGTGGGAAGCTTATGCCAACCGGCTGCGCGGGGAAGGAAAGACGGTACTCGCCGTCGCCAAGGACGGGGAAC
CGGTCGCCGTACTCGGCGTCATCGACGAAGCGCGGCCGGAAAGCCGCGGGGTCATCGGCAAGCTGCATGAGCTTGGCATC
CGGAAGACCGTCATGCTGACCGGGGACAACCGCGACACCGCCGCCGCCGTCGCCCGGCAAGCCGGCATCGATGACGTCAG
GGCAGGTCTCATGCCCGAGGACAAACTGGAAGCGATCCGCGATCTCGCGTCCGAATACGGCGCTGTCGCAATGGTCGGCG
ACGGCGTCAACGACGCGCCGGCGCTGGCCGCCGCGACCGTCGGCATCGCGATGGGCGGAGCGGGCACCGACGCCGCGCTC
GAGACGGCGGATATCGCGCTGATGGGCGACGATCTCGGCAAGCTGCCGTACGCGATCCGGCTCAGCCGCAAGACGCTGGC
CGTTATCCGGCAGAACATCGCGTTCGCCTTGATCGTGAAGCTCGCCGCCTTGCTGCTCGTCGTTCCGGGATGGCTGACAA
TCTGGATTGCCATCCTGTCCGACATGGGCGCGACGCTGATCGTCGCGCTGAACGCCATGCGCCTCATGCGCGTGCGGGCA
TGA

Protein sequence :
MARHAAPESGITKVYRVEGFTCANCAGKFEENVKRLPGVLDAKVNFAAAKITVTGEATIAELEKAGAFERLKVRPDTGDI
ATGGNSGKARGAAAFLRRHGSLLAGAALLAAGCLARLALGGHHPVTAAAFAASIVVAGHRLFRTGLNNLIRLDFDMRTLM
TVAIIGAALIGEWTEGAVVVILFALSEALERYSMERARRSIRSLMELAPREAPVLRDGREMTVRTDEIEVGDTLIVRPGA
KIAMDGIVASGTSAVNQAAITGESVPVPKSPGDEVFAGTLNGEGLLHVRVARLAQDSTISRIIRLVEEAQEGRAPAQAFV
DKFAKYYTPVIIAAAALIAVVPPLISGGGWLDWLYQGLAVLVVGCPCALVISTPIAIVSAIGSAAGRGVLIKGGIHLEQL
GAVKAIAFDKTGTVTQGIPRLTDVRLFGESVDRRDLLRIAAALEHRSGHPLAAAVTGAAREEGIDFPGTIVDNFTSVTGR
GIEGETEGARYRIGSPEWIRIGTDARMEGEWEAYANRLRGEGKTVLAVAKDGEPVAVLGVIDEARPESRGVIGKLHELGI
RKTVMLTGDNRDTAAAVARQAGIDDVRAGLMPEDKLEAIRDLASEYGAVAMVGDGVNDAPALAAATVGIAMGGAGTDAAL
ETADIALMGDDLGKLPYAIRLSRKTLAVIRQNIAFALIVKLAALLLVVPGWLTIWIAILSDMGATLIVALNAMRLMRVRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 60
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 60
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 60

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Theco_1647 YP_007212779.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0298 Protein 4e-100 49
Theco_1647 YP_007212779.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0092 Protein 1e-92 44
Theco_1647 YP_007212779.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0124 Protein 5e-85 44
Theco_1647 YP_007212779.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0461 Protein 1e-81 43