Gene Information

Name : Sinac_7194 (Sinac_7194)
Accession : YP_007206937.1
Strain : Singulisphaera acidiphila DSM 18658
Genome accession: NC_019892
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase/cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 9115700 - 9116860 bp
Length : 1161 bp
Strand : -
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme

DNA sequence :
ATGACCGAAGAAGCGTCGCGCCCCCTCGGTTTTTCGACCCTCGCCATTCACGAAGGCCAAGGTGCCGATCCCGCCACGGG
AGCGACCGTGGTGCCGATCTACGCCACCTCGACATTCACCCAAGAGGCGCCTGGAGAGCACAAGGGTTACGAGTACTCGC
GCAGCGGTAACCCGACCCGCGCGGCTCTGGAGAGCTGTCTCGCCGCCCTCGAAGGGGGAGAGCAGGGGTTGGCGTTCGCG
TCAGGCCTGGCCGCCAGCACGGCGGTCCTCTTGACCTTGAAGCCCGGGGATGAAGTGGTCGCCGCGTCCGACCTGTACGG
CGGGACCTACCGGCTGCTGGAGCGGGTTTTCAAGCAGTGGGGGCTGATTCCCCGCTACACCGACGACATCAACCCCGAAG
GGTTTGCCCGCGCCGTCACGCCCGCCACGAAGCTCGTCTGGATCGAAACGCCGACCAACCCCCTGCTGCAAGTTCTCGAC
ATTGCGGCGATCGCCGAGATTGCGCACCGGGCCGGGGCCTTGCTCGCGGTGGATAACACGTTTGCCTCCCCTTACTTGCA
ACAGCCGCTCCGCCTGGGTGCTGACATCGTGGTGCATAGCACGACCAAGTATCTGGGCGGCCACTCCGACGTGGTCGGTG
GAGCCGTGATCGGTTCGCGTGCCCTCCTCGAGCCGATTCGGTTCTATCAGAACGCCGCGGGAGGGGTCCCCGGCCCCTTC
GACTCCTGGCTGGTGCTCCGAGGCGCGAAGACCCTCGCGGTTCGGATGGACCGGCATTGCGCCAACGCCGCGCAACTCGC
TCCTTGGCTGGCCGAGCAGCCTGGAGTGGACCGGGTCTATTATCCGGGCCTTCCCTCGCACCCGAACCACGACCTGGCCC
GTCGGCAGATGCGTGACTTCGGCGGCATGATCAGCATCAGCCTTGCCGGCGGGGGGGAGGCGGCCAAGCGCTTGCTCACG
CGCACCAAGCTCTTCAGCCTGGCCGAGAGCCTGGGCGGAGTCGAGTCACTGATCAGCCACCCGGCCACCATGACCCACGC
CAGCATCCCGGCCGAGATCCGCAAGGCACGCGGCGTCGATGACGGCCTGGTCCGCCTGAGCGTCGGCATTGAAGACGTAG
CCGACCTCCAAGAAGACCTGCGCCAGGCCTTCGCCTCTTAA

Protein sequence :
MTEEASRPLGFSTLAIHEGQGADPATGATVVPIYATSTFTQEAPGEHKGYEYSRSGNPTRAALESCLAALEGGEQGLAFA
SGLAASTAVLLTLKPGDEVVAASDLYGGTYRLLERVFKQWGLIPRYTDDINPEGFARAVTPATKLVWIETPTNPLLQVLD
IAAIAEIAHRAGALLAVDNTFASPYLQQPLRLGADIVVHSTTKYLGGHSDVVGGAVIGSRALLEPIRFYQNAAGGVPGPF
DSWLVLRGAKTLAVRMDRHCANAAQLAPWLAEQPGVDRVYYPGLPSHPNHDLARRQMRDFGGMISISLAGGGEAAKRLLT
RTKLFSLAESLGGVESLISHPATMTHASIPAEIRKARGVDDGLVRLSVGIEDVADLQEDLRQAFAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-80 50
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-81 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-59 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sinac_7194 YP_007206937.1 cystathionine beta-lyase/cystathionine gamma-synthase BAC0207 Protein 2e-73 49