Gene Information

Name : Sinac_6246 (Sinac_6246)
Accession : YP_007206036.1
Strain : Singulisphaera acidiphila DSM 18658
Genome accession: NC_019892
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 7847210 - 7848685 bp
Length : 1476 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGGCGACTGTCACAGAAGCTCGACGCGCAACGCGGCGGGCGCTTCAGACGAAGCTCTTGATTGACGGCAAGTGGCGCGA
CAGTCTGAGCGGCAAGACGTTCGACACGGTCAACCCGGCGACGGAAGAGGTCATCGCCCAGGTTGCCGAGGGGGATGCCG
CCGATATCGACCTGGCGGTCAAAGCGGCTCGCAAAGCGTTCGACTCCGGCCCTTGGCGGAAGATGGACGCTCGCGATCGC
GGCCGCTTGATGAACCGGTTCGCCGACCTGATCGAGGAGAACGTCGACGAGCTGGCCGAGCTTGAGACCTTGGATAACGG
CAAGCCGATCGGCGAGAGCCGCCACGCTGACCTCCCCCTGGTGATCGACTGCTTCCGCTACTACGCCGGTTGGGCTGACA
AAATCAGCGGCCAGACCGTGCCGATCCGTGGGAATTTCTTCTGCTACACCAAACGCGAGCCGATCGGGGTTGCGGGGCAG
ATCATTCCCTGGAATTTCCCGATGCTGATGGTCGCCTGGAAGTGGGGCCCCGCCTTGGCCGCGGGCTGTACGGTGGTGCT
CAAGCCCGCCGAGCAGACCCCCTTGAGCGCCCTTCGGCTGGGTGAGCTGGCCCTCGAAGCCGGTTTCCCCGCAGGTGTGG
TCAACATTGTCCCCGGCTTCGGCGAGACCGCCGGTGCGGCCCTGGTCGCGCACCCGGGCGTGGACAAGATTGCCTTCACC
GGTGAGGGGCGCACGGCCCAGATCATCATGCGATCGGCGGCCGAGACACTCAAGCGGATCACGTTTGAACTCGGCGGCAA
GAGCCCCAACATCGTGTTCGCCGACGCCGACCTCGACGCAGCCATTGAGGGAGCCGTACTCGGGCTCTATCTCAACCAGG
GCCAGTGCTGCTGCGCGGGGAGCCGGCTGTTCGTTCAGGACTCGGTCTACGATCAATTCGTCGATCGGCTGGCGACGAAG
GTCAACGATCGCAAGCTTGGTGATCCGTTCGACCCCACGACCCAGCAAGGGCCGCAAGTCGACAAGGCCCAGTTCGACAA
GATCCTGTCCTACATCGCCAAGGGACGCGAACAAGGCGCGCGTTGCGTGGCCGGGGGCGAGCGGCACGGCGACAAGGGCT
TTTTCATCAAGCCGACGATCTTCGCCGACGTGAAGGACGACATGGCGATCGCCTGCGACGAGATCTTCGGGCCGGTCTTG
TCGGTGATCAAGTTCAAGGAAATCGACGAGGTCATCGAACGCGCCAACACCACGGACTTCGGCCTGGCCGCCGCCGTCTG
GACCCGCGACATCGGCAAAGCTCATGCGGTTGCCGATCGGGTTCGTGCGGGGACCGTCTGGGTGAACTGCTACGACGTGT
TCGATGCCGCTGCCCCGTTTGGCGGGTTCAAGCGGAGCGGGATCGGCCGTGAGTTGGGTGAGAAGTCGCTCGATAACTAC
ACCGAGCTCAAGACGGTGACCGTGGCCCTGGATTGA

Protein sequence :
MATVTEARRATRRALQTKLLIDGKWRDSLSGKTFDTVNPATEEVIAQVAEGDAADIDLAVKAARKAFDSGPWRKMDARDR
GRLMNRFADLIEENVDELAELETLDNGKPIGESRHADLPLVIDCFRYYAGWADKISGQTVPIRGNFFCYTKREPIGVAGQ
IIPWNFPMLMVAWKWGPALAAGCTVVLKPAEQTPLSALRLGELALEAGFPAGVVNIVPGFGETAGAALVAHPGVDKIAFT
GEGRTAQIIMRSAAETLKRITFELGGKSPNIVFADADLDAAIEGAVLGLYLNQGQCCCAGSRLFVQDSVYDQFVDRLATK
VNDRKLGDPFDPTTQQGPQVDKAQFDKILSYIAKGREQGARCVAGGERHGDKGFFIKPTIFADVKDDMAIACDEIFGPVL
SVIKFKEIDEVIERANTTDFGLAAAVWTRDIGKAHAVADRVRAGTVWVNCYDVFDAAAPFGGFKRSGIGRELGEKSLDNY
TELKTVTVALD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-85 49
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-94 47
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-93 46
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-95 46
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-95 46
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-95 46
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-79 43
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 8e-75 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sinac_6246 YP_007206036.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 3e-93 46