Gene Information

Name : Sinac_5995 (Sinac_5995)
Accession : YP_007205801.1
Strain : Singulisphaera acidiphila DSM 18658
Genome accession: NC_019892
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 7538470 - 7539942 bp
Length : 1473 bp
Strand : +
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGGCCCAAACCGCGACGGCCCCACGGGCCACTCCGGCCATTCGTCACACAAAGCTCCTGATCGACAATCAGTGGGTGGA
TCCCATCGAGGGGGGAGACTTCGAGACCTATAATCCCGCCACCGGCGAAGTCATCGCTCGGGTGGGCGCGGGGACAGCAG
CCGACGTGGATAAGGCGGTCAAGGCCGCCCGTCGCGCACTCGAGTCGGGCCCCTGGGCCACCATGGACGCGGCCGAACGA
GGCCGCTTGATGTACGAGTTGAGCGACCTCGTCGAGCGCAATGGCGCCGAGCTCGCCGCACTCGAGTCGCTCAACTCCGG
CAAGACGATCACCGACTCCCTGGGGGATATTGAAGGGGTCGTCAACACCCTCCGCTACTATGCCGGCTGGGCCGACAAGA
TCGAAGGTAAGACGCTGCCGGTGCGCGGTAGCTTTCTCTCCTACACGCTGAGACAGCCCGTCGGCGTCGTCGGCCAGATC
ATCCCCTGGAATTTCCCACTGTTGATGCTCGCCTGGAAGTGGGGCCCCGCCCTCGCCTGCGGCAACACCGTGGTGATGAA
GCCCGCCGAGCAGACCCCCTTGACCGCGCTCCGGATCGCCGACCTGGCGATCGAGGCCGGATTCCCCGCGGGCGTACTCA
ACATCATCAACGGATTCGGTGAAACGGCCGGCGCGGCCCTGGTGGCGCATCCGGACGTCGACAAGATCGCCTTCACCGGC
CACGTCGATACCGCCAAGATCATCCAGCGCCAGGCGGCCGAGACGCTCAAGCGAACCACGTTCGAGCTCGGCGGCAAGAG
CCCCAACGTGATCTTCGCCGACGCCAACATCGAGGACGCCGTCGCCGGCGCCTTCCACGCCATCTACTTCCACGGCGGCC
AGTGCTGCACCGCGGGGAGCCGGCTCTTCGTCGAACAGAAGATCCACAAGGAGTTCGTCCAGCGCCTGGCCGAGAAAGCC
AAGACGCGAACGATTGGCGATCCCCTCAACCCGGCCACCGAGCAAGGTCCGCAAGTCTCACAAGAGCAACTCGACAAGAT
CCTCCACTACGTCGACCTTGGCCAGAAGCAAGGGGCCAAGCTCCTCTCCGGCGGCGGACGCGTCGGCGACCGTGGATTCT
TCGTCGAGCCAACCATCTTTGACAACGTCAAAGATGACATGGCGATTGCGCGTGACGAAATCTTCGGGCCCGTCGTCAGC
GTCCTCCCCTTCACGGGAGTCGACGAGGTGGTCGAACGATCGAATAACACTTCGTACGGCCTGGCCGCTGCGATCTGGAC
CAAGGACATCGACAAGGCCCACCTGTTCGCCAAACGGGTCAAGGCTGGAACCGTCTGGGTCAACTGCTATCACGTTGTCG
ATACCACGACCCCGTTCGGCGGTTTCAAGATGTCCGGGCAAGGCCGCGAGAACGGCGAAGCCGCGCTCGAGCACTACAGT
GAAATGAAGACCGTCACCGTCAAGCTCGGTTGA

Protein sequence :
MAQTATAPRATPAIRHTKLLIDNQWVDPIEGGDFETYNPATGEVIARVGAGTAADVDKAVKAARRALESGPWATMDAAER
GRLMYELSDLVERNGAELAALESLNSGKTITDSLGDIEGVVNTLRYYAGWADKIEGKTLPVRGSFLSYTLRQPVGVVGQI
IPWNFPLLMLAWKWGPALACGNTVVMKPAEQTPLTALRIADLAIEAGFPAGVLNIINGFGETAGAALVAHPDVDKIAFTG
HVDTAKIIQRQAAETLKRTTFELGGKSPNVIFADANIEDAVAGAFHAIYFHGGQCCTAGSRLFVEQKIHKEFVQRLAEKA
KTRTIGDPLNPATEQGPQVSQEQLDKILHYVDLGQKQGAKLLSGGGRVGDRGFFVEPTIFDNVKDDMAIARDEIFGPVVS
VLPFTGVDEVVERSNNTSYGLAAAIWTKDIDKAHLFAKRVKAGTVWVNCYHVVDTTTPFGGFKMSGQGRENGEAALEHYS
EMKTVTVKLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-85 46
hpaE AAO17179.1 HpaE Not tested tcd island Protein 5e-79 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-78 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-81 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-81 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-81 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-80 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sinac_5995 YP_007205801.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 7e-79 42