Gene Information

Name : Sinac_1188 (Sinac_1188)
Accession : YP_007201274.1
Strain : Singulisphaera acidiphila DSM 18658
Genome accession: NC_019892
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1497764 - 1499485 bp
Length : 1722 bp
Strand : -
Note : PFAM: Amidohydrolase family; Urease alpha-subunit, N-terminal domain; TIGRFAM: urease, alpha subunit

DNA sequence :
ATGTCGAAACTCTCGCGCAAGCAGTATGTGGATCTCTACGGCCCGACCGTGGGAGACAAGATCCGCCTAGGTGACACCGA
TCTTTATATCGAGATTGAACGTGACCTGCGGACCTTCGGCGACGAGCTGCAATACGGCGGCGGGAAGACCTTGCGCGACG
GCATGGGGTCGGACAACCAGGTCACGCAGGCCTCCGGCTGCCTCGACATGGTCATCACCAACGTCACGGTTCTGGACCCG
ATCTTGGGGGTGGTCAAGGCCGATGTCGGGATTCGCAACGGCAAGATCGTCGGCATCGGCAAGGCGGGCAACCCGAGCAC
GATGGACAACGTGACCCCTGGGCTGACGACCGGGACCGCCACCGACGCCATCGCCGGGGAACACCTGATCCTCACGGCCG
CCGGGATGGATGGACACATCCATTACATCAGTCCCCAGCAGGTTTGGTCTGCGCTCAGCAACGGGATCACCACCTTCTGG
GGAGGGGGCATCGGCCCGTCCGACGGCACCAACGGCGTCACCACCACCAACGGCCCCTGGAACCTGGAGATGATGCTCCG
GGCCGTGGAGGGCTTGCCAATCAACTTTGGATTCCAGGGCAAGGGCAACAGTACTGGGATCGGTCCGCTCGTCGAGCAAC
TCGAAGGGGGCGCGGCCGGGTTCAAGATCCACGAAGACTACGGCACCACCCCCGCCAACATCCGCGCCTGCCTGCGAGTC
GCCGACAATTACGACGTCTCCGTCTCGATTCACACCGACACCCTGAACGAGGCCGGCTTCGTCGAGGATACGATCGCCGC
CTTCGACGGCCGGACGATCCATACCTATCACAGCGAAGGGGCCGGCGGCGGCCATGCACCCGACTTGCTCAAAGTCGTCG
GCCAGCCGAACGTCCTGCCAAGCTCGACCAACCCGACCCTGCCGTGCGGGGTCAACTCGGTGTCCGAGCTTTTTGATATG
ATTATGGTCTGCCACAACCTGAGCCCCAAGATCCCCTCGGACGTCGCATTTGCCGAGAGCCGGGTCCGGGGTGAGACGAT
CGTCGCCGAGAGCGTCCTCCACGACATGGGGGCGATCTCAATGATCACCAGCGACTCCCAGGCGATGGGCCGGGTCGGCG
AGACCTGGCTGCGGACGATGCAGACCGCAGACATCATGAAGAAGACGCGCGGGCCGCTCCCCGAGGACGCCTCCTCGGGC
AACGATAACAACCGCGTCCTCCGGTTCGTGGCCAAGGTCACGATCAATCCGACGCTAACGGTGGGGATCTCCGACGTCCT
CGGCTCGATCGCGCCGGGCAAAATGGCCGACCTGGTGCTCTGGGAACCCGCCTTTTTCGGCGCCAAGCCAAAGCTGGTAC
TCAAAGGCGGGATGATCGTCTGGGCCAACATGGGCGATCCCAACGCCTCCCTGCCGACCTGCCAACCGATGATGTTCCGC
CCGATGTTCGGCGCCTTCGGCTCAGCGCTGGCCAAGACCTGCGTCACGTTCGTCTCGCGTGCCTCTTACGAGCGGGGGAT
CGCCGAGAAGTACGGCCTCCAGCGCATCGTTCGGCCGGTCTACGGAACCAGAACCTTGACCAAGCGGCACATGATTCGCA
ATGACTTCCTCCCCAAGATCGACGTCAATCCACAGACTTTCGCCGTAACCGTGGATGGCGTGCATGCGACTGTCACGCCC
CCCAAGACGATTGCCCTGAATCAGCTTCACTTCTTCGGTTGA

Protein sequence :
MSKLSRKQYVDLYGPTVGDKIRLGDTDLYIEIERDLRTFGDELQYGGGKTLRDGMGSDNQVTQASGCLDMVITNVTVLDP
ILGVVKADVGIRNGKIVGIGKAGNPSTMDNVTPGLTTGTATDAIAGEHLILTAAGMDGHIHYISPQQVWSALSNGITTFW
GGGIGPSDGTNGVTTTNGPWNLEMMLRAVEGLPINFGFQGKGNSTGIGPLVEQLEGGAAGFKIHEDYGTTPANIRACLRV
ADNYDVSVSIHTDTLNEAGFVEDTIAAFDGRTIHTYHSEGAGGGHAPDLLKVVGQPNVLPSSTNPTLPCGVNSVSELFDM
IMVCHNLSPKIPSDVAFAESRVRGETIVAESVLHDMGAISMITSDSQAMGRVGETWLRTMQTADIMKKTRGPLPEDASSG
NDNNRVLRFVAKVTINPTLTVGISDVLGSIAPGKMADLVLWEPAFFGAKPKLVLKGGMIVWANMGDPNASLPTCQPMMFR
PMFGAFGSALAKTCVTFVSRASYERGIAEKYGLQRIVRPVYGTRTLTKRHMIRNDFLPKIDVNPQTFAVTVDGVHATVTP
PKTIALNQLHFFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-139 55
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-139 55
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-132 52
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-132 52
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 5e-132 52
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-132 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sinac_1188 YP_007201274.1 urease subunit alpha VFG0270 Protein 7e-139 56