Gene Information

Name : Cyan10605_1597 (Cyan10605_1597)
Accession : YP_007161749.1
Strain : Cyanobacterium aponinum PCC 10605
Genome accession: NC_019776
Putative virulence/resistance : Resistance
Product : chloramphenicol O-acetyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.3.1.28
Position : 1925768 - 1926400 bp
Length : 633 bp
Strand : -
Note : PFAM: Bacterial transferase hexapeptide (three repeats); COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: cyh:Cyan8802_2073 VatB; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: VatB

DNA sequence : 
ATGACTTATCCTAATCCAGAGCAAATATATCCTTTAACTAATTATAGTCGTCTTTGTTTCTTAAAAAATATCGTTAAAAA
TCCAAATATCATTGTTGGTGATTTTACTTACTACGATGATTTTGAAAATCCTTTAAATTTTGAAAAAAACGTATTATATC
ACTTTGATTTTATTGGTGATAAATTAATTATCGGTAAATTTTGTGCTATTGCTAGTAATGTTAAATTTATTATGAACGGA
GCAAATCATCCTTTGAATAATTTCACCACCTATCCTTTCGCTATTTTCGGTAATGGATGGGAAGATAAAATGTCAGTGGA
AGCAACATCAAAAGGAGATACTATCATTGGAAATGATGTGTGGCTAGGTTACAATACAACGATTATGCCCGGTGTGAAAA
TTGGGGATGGTGTCATTGTAGCGACTAATTCGATGGTAACAAAAGACATTCCTGCTTATCATATTGTTGGCGGTAATCCT
GCTCAAATTATTAGAAAACGTTTTGATGATGAAATAATCAATTTTTTATTAGAATTAAAATGGTGGGATTGGACTTTGGA
AAAAATCACAAAATATATTCCCGTATTATGCAGTAATAATATTCAAGAACTAAAAAAAATTGTAGAGGAATAA

Protein sequence : 
MTYPNPEQIYPLTNYSRLCFLKNIVKNPNIIVGDFTYYDDFENPLNFEKNVLYHFDFIGDKLIIGKFCAIASNVKFIMNG
ANHPLNNFTTYPFAIFGNGWEDKMSVEATSKGDTIIGNDVWLGYNTTIMPGVKIGDGVIVATNSMVTKDIPAYHIVGGNP
AQIIRKRFDDEIINFLLELKWWDWTLEKITKYIPVLCSNNIQELKKIVEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catB3 AET25385.1 chloramphenicol acetyltransferase Not tested PAGI-2(C) Protein 1e-32 46
catB3 AFG30108.1 chloramphenicol acetyltransferase Not tested PAGI-2 Protein 1e-32 46
catB8 YP_005797132.1 chloramphenicol acetyltransferase Not tested AbaR4e Protein 8e-32 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cyan10605_1597 YP_007161749.1 chloramphenicol O-acetyltransferase AM180355.1.gene2499. Protein 1e-47 50
Cyan10605_1597 YP_007161749.1 chloramphenicol O-acetyltransferase AY740681.1.gene5.p01 Protein 7e-33 46
Cyan10605_1597 YP_007161749.1 chloramphenicol O-acetyltransferase AF322577.2.gene4.p01 Protein 7e-33 46
Cyan10605_1597 YP_007161749.1 chloramphenicol O-acetyltransferase JF268688.1.gene6.p01 Protein 5e-29 46
Cyan10605_1597 YP_007161749.1 chloramphenicol O-acetyltransferase AY123251.gene2.p01 Protein 3e-32 45
Cyan10605_1597 YP_007161749.1 chloramphenicol O-acetyltransferase CP001581.1.gene990.p Protein 2e-33 43
Cyan10605_1597 YP_007161749.1 chloramphenicol O-acetyltransferase NC_002516.2.878374.p Protein 6e-30 41