Gene Information

Name : Anacy_4916 (Anacy_4916)
Accession : YP_007159167.1
Strain : Anabaena cylindrica PCC 7122
Genome accession: NC_019771
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 5566149 - 5567918 bp
Length : 1770 bp
Strand : -
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015795:IPR008279; KEGG: naz:Aazo_2208 pyruvate kinase;

DNA sequence : 
ATGCAATTAAGAGATTCTCTGCGCCGAACCAAAATTGTTGCTACTATTGGGCCTGCTACCAGCAGTCCAGAAATGCTGAA
GGCAATTATTGAAGCGGGTGCAACAACACTGCGGCTAAACTTCTCCCACGGAACTCATGCTGACCATCAGCGTAGTATTC
GCCTAATTCGGCAAACTGCTTTTGAACTCAATAGACCAGTAGCAATTCTCCAAGATTTGCAAGGGCCAAAAATTCGCTTG
GGTAAGTTTGAAAATGGTTCTATAATTTTGGCGAAGGGCGATCGCTTCACCTTAACAAATCGTCCAGTTGTAGGAACCCA
AGAAATCAGTTGCGTTACCTACGATTATTTAGCAGATGAAGTCCCCGTCGGTGCCAAAATCCTCCTCGATGATGGACGAG
TGGAAATGGTCGTGGAAGACATTAACCAGGACAAAGGCGATTTGCATTGTCGCATTACTGTACCTGGTAAACTTTCTAAC
AACAAAGGTGTAAACTTTCCGGGAGTTTACTTATCAATTAAAGCTATGACCGACAAAGACCGCGAGGATCTGATGTTTGG
TCTAGATCAAGGTGTAGACTGGGTAGCACTTTCCTTTGTCCGTAACCCCCAGGACATGATCGAAATCAAAGAGCTAATTT
CTAGCACAGGCAAAAATGTCCCTGTAATTGCCAAAATTGAAAAGCACGAAGCCATTGAACAAATGGAAGAAGTTCTGTCT
TTGTGTGACGGCGTAATGGTTGCTAGAGGTGACTTAGGCGTGGAACTACCAGCGGAAGATGTACCCATACTGCAAAAACG
GCTAATTGCTACAGCCAACCGTTTGGGTATCCCCATTATTACCGCTACCCAAATGTTAGATAGCATGGTCAGCAACCCCC
GTCCTACCCGTGCGGAAGTCTCCGATGTCGCAAACGCGATTTTAGACGGTACAGACGCGGTAATGCTCTCCAATGAAACT
GCTGTTGGTAGTTTCCCGGTGGAAGCTGTAGCCACAATGGCCAGAATAGCAGAACGCATTGAACAGGAAGAAACCCTAAA
CGCTAACTCCCGTCAATCAAGAGATAAAAGGCGTTCTATTCCCAATGCTATTAGCCAAGCAGTTGGTCAAATTGCTGAAA
ATTTGGGCGCAGCGGCAATTATGACTTTGACTCAAACCGGTGCTACAGCCCGCAACGTTTCTAAATTTCGTCCCAAAACG
CCAATTTTAGCCATCACACCCCATGTAAACGTAGCAAGGCAGTTGCAAATGGTCTGGGGAGTAAGACCGCTGTTGGTACT
AGAACTACCTTCCACAGGTCAGACATTCCAAGCCGCTATAAATGTGGCTCAGGAGAAAAATCTCTTGAGTGAAGGTGATT
TGGTAGTGATGACTGCTGGTACACTTCAGGGGGTTTCTGGGTCAACAGACTTGATTAAGGTGGAAGTGGTGACTGCTGTA
CTGGGTCAGGGCATTGGTCTAGGACAAGGTTCTGTCAGTGGTCGTGCCAGAGTAGCACATACTGCTATGGATGCAAGTAA
CTTTAACCCTGGAGATATTTTGGTCGCATCCCGCACTAGTGTAGATTTTGTGGAAGCGATTCGCAAAGCTGGGGGAATTA
TTACTGAAGAAGAAAGTCTCTCAAGTCATGCAGCCGTGATTGGTTTACGTCTCGGTGTACCAGTGATTGTCGGGGTGAAG
GAAGCGACAAAGGTAATTAAAGATGGGGCAATTTTGACTTTAGATATGCAACGAGGTTTAGTTTACTCTGGGGCTGTGGG
AACACCTTAA

Protein sequence : 
MQLRDSLRRTKIVATIGPATSSPEMLKAIIEAGATTLRLNFSHGTHADHQRSIRLIRQTAFELNRPVAILQDLQGPKIRL
GKFENGSIILAKGDRFTLTNRPVVGTQEISCVTYDYLADEVPVGAKILLDDGRVEMVVEDINQDKGDLHCRITVPGKLSN
NKGVNFPGVYLSIKAMTDKDREDLMFGLDQGVDWVALSFVRNPQDMIEIKELISSTGKNVPVIAKIEKHEAIEQMEEVLS
LCDGVMVARGDLGVELPAEDVPILQKRLIATANRLGIPIITATQMLDSMVSNPRPTRAEVSDVANAILDGTDAVMLSNET
AVGSFPVEAVATMARIAERIEQEETLNANSRQSRDKRRSIPNAISQAVGQIAENLGAAAIMTLTQTGATARNVSKFRPKT
PILAITPHVNVARQLQMVWGVRPLLVLELPSTGQTFQAAINVAQEKNLLSEGDLVVMTAGTLQGVSGSTDLIKVEVVTAV
LGQGIGLGQGSVSGRARVAHTAMDASNFNPGDILVASRTSVDFVEAIRKAGGIITEEESLSSHAAVIGLRLGVPVIVGVK
EATKVIKDGAILTLDMQRGLVYSGAVGTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-89 46
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-90 46
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-90 46
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-89 46
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-61 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Anacy_4916 YP_007159167.1 pyruvate kinase VFG0479 Protein 4e-90 46