Gene Information

Name : pykA (EFS1_0874)
Accession : YP_007152666.1
Strain : Enterococcus faecalis Symbioflor 1
Genome accession: NC_019770
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 897284 - 899041 bp
Length : 1758 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAAAACGAAAATCGTATGTACGATTGGACCAGCTAGTGAATCCGTTGATATGCTAGTAAACTTAATTAATGCAGG
TATGAATGTTTGCCGTTTGAACTTTTCACATGGTGACTACGAAGAGCATGGTGCTCGTATTAAAAACATTCGTGAAGCTG
TAAAAATTACAGGGAAACGCGTAGCGATCTTACTAGATACAAAAGGTCCTGAAATCCGCACAAATGACATGGAAAATGGC
GCAATCACAATGAAAATTGGTGACTCAGTACGTATTTCTATGACAGAAGTTTTAGGAACAAATGAAAAATTCTCAATCAC
TTATCCAGAATTAATCAATGATGTAAACGTAGGTTCACACATTCTTTTAGATGATGGTTTAATCGATTTAGAAGTAACTG
ATATCGACCGTGATGCAAACGAAATCGTAACAGTTGTTAAAAACGAAGGCGTCTTGAAAAACAAAAAAGGCGTTAACGTA
CCAGGCGTTTCTGTAAACTTACCAGGGATCACTGAAAAAGATGCTAACGATATCCGTTTCGGAATTGGTCAAGGAATTGA
CTTTATCGCAGCTAGCTTCGTTCGTCGTGCTTCTGACGTTTTAGAAATCACTAAAATTTTAGAAGAAGAAAACGCAACAC
ACATCCAAATCATTCCTAAAATCGAAAACCAAGAAGGTATCGATAATATCGATGAAATCTTAAAAGTTTCTGATGGTTTA
ATGGTTGCTCGTGGTGACATGGGTGTTGAAATTCCAACAGAAGATGTTCCAGTTGTCCAAAAAGCTTTAATTAAAAAATG
TAATGCTTTAGGTAAACCAGTTATCACTGCAACACAAATGTTAGATTCAATGCAACGTAACCCACGTCCAACACGTGCGG
AAGCAAATGACGTAGCAAACGCAATCTACGATGGAACAGATGCAGTAATGTTATCAGGCGAAACTGCAGCAGGGGATTAC
CCATTAGAAGCTGTTCAAACAATGGCTCGTATTGCAGTTCGTACAGAAGAAACATTAGTTAACCAAGATTCATTCGCATT
GAAATTATATAGCAAAACAGATATGACTGAAGCAATCGGACAATCTGTTGGCCATACAGCACGTAACTTGGGTATCCAAA
CAATCGTTGCGGCAACAGAATCAGGCCATACAGCACGTATGATCTCTAAATACCGTCCAAAAGCACATATCGTTGCAATT
ACGTTCTCAGAACAAAAAGCACGTAGCTTATCATTATCATGGGGTGTTTACGCAACAGTTGCTGACAAACCATCAAGCAC
AGATGAAATGTTTAATTTAGCTTCAAAAGTATCACAAGAAGAAGGTTATGCTTCAGAAGGTGATTTAATCATTATCACTG
CTGGTGTTCCAGTTGGCGAAAAAGGCACAACAAACTTAATGAAAATTCAAATGATCGGTTCTAAATTAGTTCAAGGTCAA
GGTGTCGGCGAAGAAGCAATTATTGCAAAAGCCGTTGTAGCAGGAACTGCTGAAGAAGCAGTTGCTAAAGCGACTGAAGG
AGCTATTTTAGTTACAAAAACAACAGATAAAGAATACATGCCTGCAATTGAAAAAGCATCAGCATTAGTTGTTGAAGAAG
GTGGTTTAACTTCTCATGCAGCTGTTGTAGCGATTGCGCAAAATATTCCAGTTATCGTAGGTGCTGCAGATGCAACATCA
TTAATTAATAATGACGAAGTGATTACTGTTGATCCTCGTCGTGGTATTGTTTACCGCGGAGCAACAACAGCTATCTAA

Protein sequence :
MKKTKIVCTIGPASESVDMLVNLINAGMNVCRLNFSHGDYEEHGARIKNIREAVKITGKRVAILLDTKGPEIRTNDMENG
AITMKIGDSVRISMTEVLGTNEKFSITYPELINDVNVGSHILLDDGLIDLEVTDIDRDANEIVTVVKNEGVLKNKKGVNV
PGVSVNLPGITEKDANDIRFGIGQGIDFIAASFVRRASDVLEITKILEEENATHIQIIPKIENQEGIDNIDEILKVSDGL
MVARGDMGVEIPTEDVPVVQKALIKKCNALGKPVITATQMLDSMQRNPRPTRAEANDVANAIYDGTDAVMLSGETAAGDY
PLEAVQTMARIAVRTEETLVNQDSFALKLYSKTDMTEAIGQSVGHTARNLGIQTIVAATESGHTARMISKYRPKAHIVAI
TFSEQKARSLSLSWGVYATVADKPSSTDEMFNLASKVSQEEGYASEGDLIIITAGVPVGEKGTTNLMKIQMIGSKLVQGQ
GVGEEAIIAKAVVAGTAEEAVAKATEGAILVTKTTDKEYMPAIEKASALVVEEGGLTSHAAVVAIAQNIPVIVGAADATS
LINNDEVITVDPRRGIVYRGATTAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-104 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-104 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-104 52
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-104 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_007152666.1 pyruvate kinase VFG0479 Protein 4e-105 52