Gene Information

Name : Cal6303_0483 (Cal6303_0483)
Accession : YP_007135532.1
Strain : Calothrix sp. PCC 6303
Genome accession: NC_019751
Putative virulence/resistance : Resistance
Product : chloramphenicol O-acetyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.3.1.28
Position : 572516 - 573148 bp
Length : 633 bp
Strand : -
Note : PFAM: Bacterial transferase hexapeptide (three repeats); COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: amr:AM1_5174 acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: Acetyltransferase

DNA sequence : 
ATGGAATATCCAGATCCTAAAGTTATTCATCCCTTGAAAGAATTTCCCCAAGTCTGTTTTATTAAAAATGTCGTTTCCAA
TCCCAATATCATTATCGGAGACTATACCTATTATGATGATCCGGAAAACTCGGAAGATTTTGAGCGCAACGTACTCTATC
ACTTTCCCTTTATCGGTGATAAGTTGATTATCGGCAAATTTTGTGCTTTAGCCACAGCTATAAAATTTATCATGAACGGT
GCAAATCACAAGCTTTCTGGGTTCTCAACTTATCCATTTGCAATTTTTGGTAGTGGTTGGGAATGTGTAGCACCCCAACC
CGATGAATTCCCCTTTAAAGGTGATACTGTAGTTGGAAATGATGTGTGGATTGGATATAAAGCGGTAATTATGCCGGGAG
TCAAGATTGGTGATGGTGCGATTATTGCGGCAAAGTCTGTAGTAACGAAAGATGTTGAACCTTACACTATTGTCGGTGGA
AATCCAGCGAATAGATTACGACAACGTTTCCCAGATGCAACTATTCAACTTTTACTGGAAATTGCTTGGTGGAACTGGGA
TATGGAAAAGATTACCAGGAATTTAGAAAGTATTGTGGGTGCGGATATCGCAGCGTTAAAAAGCTGTGTATGA

Protein sequence : 
MEYPDPKVIHPLKEFPQVCFIKNVVSNPNIIIGDYTYYDDPENSEDFERNVLYHFPFIGDKLIIGKFCALATAIKFIMNG
ANHKLSGFSTYPFAIFGSGWECVAPQPDEFPFKGDTVVGNDVWIGYKAVIMPGVKIGDGAIIAAKSVVTKDVEPYTIVGG
NPANRLRQRFPDATIQLLLEIAWWNWDMEKITRNLESIVGADIAALKSCV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catB8 YP_005797132.1 chloramphenicol acetyltransferase Not tested AbaR4e Protein 1e-30 44
catB3 AET25385.1 chloramphenicol acetyltransferase Not tested PAGI-2(C) Protein 6e-32 44
catB3 AFG30108.1 chloramphenicol acetyltransferase Not tested PAGI-2 Protein 6e-32 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cal6303_0483 YP_007135532.1 chloramphenicol O-acetyltransferase AM180355.1.gene2499. Protein 7e-44 48
Cal6303_0483 YP_007135532.1 chloramphenicol O-acetyltransferase JF268688.1.gene6.p01 Protein 4e-30 45
Cal6303_0483 YP_007135532.1 chloramphenicol O-acetyltransferase AF322577.2.gene4.p01 Protein 3e-32 44
Cal6303_0483 YP_007135532.1 chloramphenicol O-acetyltransferase AY123251.gene2.p01 Protein 4e-31 44
Cal6303_0483 YP_007135532.1 chloramphenicol O-acetyltransferase AY740681.1.gene5.p01 Protein 3e-32 44
Cal6303_0483 YP_007135532.1 chloramphenicol O-acetyltransferase NC_002516.2.878374.p Protein 1e-29 43