Gene Information

Name : Mic7113_5000 (Mic7113_5000)
Accession : YP_007124067.1
Strain : Microcoleus sp. PCC 7113
Genome accession: NC_019738
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5851383 - 5854043 bp
Length : 2661 bp
Strand : -
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA)

DNA sequence :
ATGCAGCCCACAGACCCGAACAAGTTTACGGAGACAGCCTGGAAAGCGATCGCACAATCTCAAGACGTTGCCAAACTCTT
CAAGAACCAAACGCTAGAGGTGGAGCATGTGGCGATTGCCCTGCTGGAACAAGAGGGGCTGGCGAATCTAATTCTTACCA
AGGTTACAGTTGATGTGGCTCGGTTTAAGCAACAACTGGAAGCCTTCGCCAACCGCCAACCGAAAGTGGGTACTGTTGAC
CAACTCTACCTCGGTCGCGGCTTGGATATCATGCTGGATAAGGCTGAGGGGTTCCGCACCAATTTTCAAGATGAATACAT
TGCTGTAGAACATTTGCTTTTAGCCTTAGCAGAAGATGACCGCGTCGGACGGCGGTTGCTCAAAACCCATAATGTGGATA
CCCCAAAGCTAGAAGCCGCAGCCAAAGCCACACGGGGGAGTCAAAAGGTTACTGACCAAAATCCTGAAAATCGCTACAAC
GCCCTAGAGAAGTACGGGCGGGATTTAACAGAGCAAGCTCGTAGCGGGAAACTTGACCCAGTGATTGGACGGGATGAAGA
AATTCGTCGCGTGATTCAGGTGCTTTCTCGTCGCTCTAAGAATAACCCAGTTCTGATTGGAGAGCCTGGAGTTGGGAAAA
CCGCGATCGCAGAAGCCCTGGCCCAGCGTATTGTTAATGGGGATGTTCCGGAATCCCTGAAAAACCGCCAACTCATTTCC
TTAGATATGGGCAGTCTGATTGCCGGTGCCAAATATCGAGGAGAATTTGAAGACCGACTCAAAGCTGTCCTTCGGGAAGT
GACCCACTCCGATGGTCAAATTGTCCTCTTTATCGATGAATTGCACACCGTCGTCGGTGCGGGAGCAACCCAAGGGGCAA
TGGATGCAGGAAACTTGCTCAAACCCATGCTGGCGCGGGGGGAACTGCGCTGTATTGGAGCCACTACTCTGGATGAGTAC
CGCAAGCACATTGAAAAAGACGCGGCACTGGAACGTCGCTTTCAACAAGTCTATGTCAGTCAACCCACCGTAGAGAATAC
GATTTCGATTTTGCGGGGGCTGAAGGAACGCTACGAAGTCCACCACAATGTGATTATTACGGACTCGGCGCTAGTGGCAG
CGGCTACTCTTTCTGATCGCTATATTACCGATCGATTCCTGCCCGATAAAGCCATTGACTTAGTCGATGAAGCCGCCGCC
AAGCTGAAAATGGAGATGACCTCCAAACCGGTGGAATTAGAGACCATTGAGCGACGGCTGATGCAGCTCAAGATGGAAAA
ACTGTCTCTAGATACAGAAAATCAACAGAATCTGCCCACCACCAGTAACGCCTACCGTGCTTCGCGAGAGCGCCTCGAAC
GCATTGAACAAGAAATTCTCACTCTGGAGGAAAAACACGCCACGCTGGAAGGACGGTGGGAAGAGGAGAAGAAACTTCGC
GAAGAAATCAATAACCTGAAGAAAGAAGAAGACCAAATTCGGGTACAAATTGAGCAGGCTGAACGTGCTTACGACTTGAA
TAAGGCAGCTCAACTTAAATATGGCAAGTTAGAAACATTACAGCGCGATCGCGATAGCAAAGAAGGGATGCTCTTAGAGC
TCCAAGCGGAGGGGCGTGCCTTATCCCGTGAACAAGTCACCGAGGCGGATATTGCCGAAATTGTGGCGAATTGGACGGGG
ATTCCAGTTAACCGCTTGCTAGAGACGGAACGCCAAAAGCTATTACAGCTAGAAGGGCATTTACATCAACGGGTCATTGG
GCAAACTGAAGCGGTGACTTCCGTGGCGGCAGCGATTCGTCGGGCGAGGGCGGGTATGAAAGACCCCGGACGCCCCATCG
GTTCCTTCTTGTTCCTGGGGCCAACCGGTGTGGGTAAGACGGAATTGGCAAGAGCGATCGCCCAATTCCTGTTTGACAGC
CAGGATGCCTTAGTCAGAATCGACATGTCCGAGTATATGGAAAAACACGCCGTCTCGCGGCTAGTGGGTGCGCCTCCGGG
ATATGTGGGCTATGAAGAAGGCGGTCAACTCTCGGAAGCGATTCGCCGCCGTCCTTACTCGGTGGTGCTGTTGGATGAGG
TGGAAAAGGCACACCCAGATGTGTTCAACATTTTGCTACAAGTCCTCGATGATGGACGCATTACCGACTCTCAAGGGAGA
ACGGTGGATTTTTCCAATACGATCATCGTGATGACCAGCAATATTGGCAGTGACCATATTTTAAATGTGGCTGGGGATGA
TTCGCAGTATGAAGAGATGCGCAAGCGGGTGACTGTTGCCTTACGCAAACACTTCCGTCCCGAATTTGTCAACCGTGTTG
ACGACATCATCATCTTCCACACCTTGAATCGCAGCGAACTCAGCCAGATTGTCAGGATTCAGCTCAAACGGATTGAGCGT
CTATTAGCTGACCAAAAAATTAAGCTTGAACTTTCGTCAACAGCTCAAGATTACATCGTTGAAGTCGGTTACGATCCGGT
ATACGGGGCGCGTCCACTTAAACGGGCGATTCAGCGGGAATTGGAAAATGCGATCGCGACAAAAATCCTTGAGAATACCT
TTGTTGAGGGAGACACGATTATCATTGATTGTGTCGATAACAGCCTCACCTTTAATAAAAAGGTACTACTAAGCTTATCA
GCAGTCCAAACTCCTGGCTGA

Protein sequence :
MQPTDPNKFTETAWKAIAQSQDVAKLFKNQTLEVEHVAIALLEQEGLANLILTKVTVDVARFKQQLEAFANRQPKVGTVD
QLYLGRGLDIMLDKAEGFRTNFQDEYIAVEHLLLALAEDDRVGRRLLKTHNVDTPKLEAAAKATRGSQKVTDQNPENRYN
ALEKYGRDLTEQARSGKLDPVIGRDEEIRRVIQVLSRRSKNNPVLIGEPGVGKTAIAEALAQRIVNGDVPESLKNRQLIS
LDMGSLIAGAKYRGEFEDRLKAVLREVTHSDGQIVLFIDELHTVVGAGATQGAMDAGNLLKPMLARGELRCIGATTLDEY
RKHIEKDAALERRFQQVYVSQPTVENTISILRGLKERYEVHHNVIITDSALVAAATLSDRYITDRFLPDKAIDLVDEAAA
KLKMEMTSKPVELETIERRLMQLKMEKLSLDTENQQNLPTTSNAYRASRERLERIEQEILTLEEKHATLEGRWEEEKKLR
EEINNLKKEEDQIRVQIEQAERAYDLNKAAQLKYGKLETLQRDRDSKEGMLLELQAEGRALSREQVTEADIAEIVANWTG
IPVNRLLETERQKLLQLEGHLHQRVIGQTEAVTSVAAAIRRARAGMKDPGRPIGSFLFLGPTGVGKTELARAIAQFLFDS
QDALVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLSEAIRRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRITDSQGR
TVDFSNTIIVMTSNIGSDHILNVAGDDSQYEEMRKRVTVALRKHFRPEFVNRVDDIIIFHTLNRSELSQIVRIQLKRIER
LLADQKIKLELSSTAQDYIVEVGYDPVYGARPLKRAIQRELENAIATKILENTFVEGDTIIIDCVDNSLTFNKKVLLSLS
AVQTPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-105 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 8e-107 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 6e-107 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mic7113_5000 YP_007124067.1 ATP-dependent chaperone ClpB VFG2076 Protein 8e-120 43
Mic7113_5000 YP_007124067.1 ATP-dependent chaperone ClpB VFG2084 Protein 8e-114 43